ChemicalBook >> CAS DataBase List >>Nicotredole
Nicotredole
- CAS No.
- 29876-14-0
- Chemical Name:
- Nicotredole
- Synonyms
- tryptamide;Nicotredole;N-[2-(3-indolyl)ethyl]nicotinamide;N-(2-(1H-Indol-3-yl)ethyl)nicotinaMide;N-[2-(1H-indol-3-yl)ethyl]pyridine-3-carboxamide;3-Pyridinecarboxamide, N-[2-(1H-indol-3-yl)ethyl]-;anti-inflammatory,Nicotredole,analgesic,ulcerogenic,inhibit,Inhibitor
- CBNumber:
- CB51116903
- Molecular Formula:
- C16H15N3O
- Molecular Weight:
- 265.31
- MDL Number:
- MFCD00841846
- MOL File:
- 29876-14-0.mol
- MSDS File:
- SDS
Last updated:2024-07-02 08:55:09
| Boiling point | 408.53°C (rough estimate) |
|---|---|
| Density | 1.0944 (rough estimate) |
| refractive index | 1.6500 (estimate) |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | DMSO: 25 mg/mL (94.23 mM) |
| form | Solid |
| color | Light brown to brown |
| FDA UNII | 0F1T12OCLX |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H332-H335 |
| Precautionary statements | P261-P280-P305+P351+P338 |
Nicotredole price More Price(10)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Matrix Scientific | 074574 | N-(2-(1H-Indol-3-yl)ethyl)nicotinamide 95+% | 29876-14-0 | 250mg | $416 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CHM1002549 | N-(2-(1H-INDOL-3-YL)ETHYL)NICOTINAMIDE 95.00% | 29876-14-0 | 5MG | $495.69 | 2021-12-16 | Buy |
| AK Scientific | W5233 | Nicotredole | 29876-14-0 | 5g | $698 | 2021-12-16 | Buy |
| Matrix Scientific | 074574 | N-(2-(1H-Indol-3-yl)ethyl)nicotinamide 95+% | 29876-14-0 | 1g | $899 | 2021-12-16 | Buy |
| Matrix Scientific | 074574 | N-(2-(1H-Indol-3-yl)ethyl)nicotinamide 95+% | 29876-14-0 | 5g | $2411 | 2021-12-16 | Buy |
Nicotredole Chemical Properties,Uses,Production
Biological Activity
Nicotredole (Tryptamide) is an orally active anti-inflammatory analgesic. It showed significant anti-inflammatory effects comparable to Phenylbutazone.
in vitro
Nicotredole inhibits prostaglandin synthetase activity in vitro.
in vivo
Nicotredole produces antiinflammatory effects in carrageenin-induced rat paw oedema.
It reverses pyrogen-induced hyperthermia in rats, elicits analgesic effects in rats, prolongs the time of hexobarbital sleep in rats and inhibits locomotor activity in rats and mice.
Nicotredole (ip) has LD50s of 1260 mg/kg and 1980 mg/kg for male rats and male mice, respectively.
Nicotredole (po) has LD50s of 8.5 g/kg and 9.3 g/kg for male rats and male mice, respectively.
Nicotredole (25 mg/kg; po or ip) undergoes fast absorption (t 1/2 =4.92-17.5 min) and elimination (t 1/2 =55.72-74.52 min), can reach C max (11-13 μg/cm 3 ) after 30 min, and gives AUC values in the range of 21.40-27.30 (μg?h/cm 3 ).
Nicotredole Preparation Products And Raw materials
Raw materials
Preparation Products
Nicotredole Suppliers
Global( 48)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63711 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29826 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131980 | 58 |
| Zhengzhou Guancheng Laboratory equipment Sales | 0371-88888888 272369594 | 2723695949@qq.com | China | 4968 | 50 |
| Hangzhou Molcore Biopharmatech Co.,Ltd | 400-711-5280 86-571-81025280 | sales@molcore.com | China | 9974 | 58 |
| Sichuan BaiPeng Biotechnology Co., Ltd. | 028-65791793 18140026355 | 568470422@qq.com | China | 9993 | 58 |
| Aikon International Limited | 025-58859352 18068836627 | sales01@aikonchem.com | China | 15085 | 58 |
| Shanghai Jizhi Biochemical Technology Co. Ltd. | 400-400-400-9004166 18616739031 | 3007523370@qq.com | China | 52712 | 58 |
View Lastest Price from Nicotredole manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-01-13 | Nicotredole
29876-14-0
|
US $1.00 / g | 1g | 99.0% | 100kg | Career Henan Chemical Co |
-
- Nicotredole
29876-14-0
- US $1.00 / g
- 99.0%
- Career Henan Chemical Co
29876-14-0(Nicotredole)Related Search:
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1of2
Nicotredole
tryptamide
N-(2-(1H-Indol-3-yl)ethyl)nicotinaMide
N-[2-(3-indolyl)ethyl]nicotinamide
3-Pyridinecarboxamide, N-[2-(1H-indol-3-yl)ethyl]-
N-[2-(1H-indol-3-yl)ethyl]pyridine-3-carboxamide
anti-inflammatory,Nicotredole,analgesic,ulcerogenic,inhibit,Inhibitor
29876-14-0