ChemicalBook >> CAS DataBase List >>BPN-15477
BPN-15477
- CAS No.
- 1971086-99-3
- Chemical Name:
- BPN-15477
- Synonyms
- BPN-15477;7H-Pyrrolo[2,3-d]pyrimidin-4-amine, 2-chloro-N-(4-pyridinylmethyl)-
- CBNumber:
- CB511410969
- Molecular Formula:
- C12H10ClN5
- Molecular Weight:
- 259.69
- MDL Number:
- MOL File:
- 1971086-99-3.mol
Last updated:2024-07-02 08:55:09
BPN-15477 Chemical Properties,Uses,Production
Biological Activity
BPN-15477 is a potent SMC (splicing modulator compound) that restores correct splicing of ELP1 (Elongator complex protein 1) exon 20. BPN-15477 corrects splicing of the ELP1 transcript, significantly increases the level of functional protein in vivo in all tissues, including brain. BPN-15477 can be used for frontotemporal dementia research[1].
References
[1]. Gao D, et al. A deep learning approach to identify gene targets of a therapeutic for human splicing disorders. Nat Commun. 2021 Jun 7;12(1):3332.
BPN-15477 Preparation Products And Raw materials
Raw materials
Preparation Products
BPN-15477 Suppliers
Global( 3)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Tianjin Kailiqi Biotechnology Co., Ltd. | 15076683720 | klq@cw-bio.com | China | 3717 | 55 |
| Suzhou youruike Chemical Pharmaceutical Technology Co., Ltd | 15317229551 | 15151849396@163.com | China | 997 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24017 | 58 |
BPN-15477
7H-Pyrrolo[2,3-d]pyrimidin-4-amine, 2-chloro-N-(4-pyridinylmethyl)-
1971086-99-3