LICOCHALCONE-A
- CAS No.
- 58749-22-7
- Chemical Name:
- LICOCHALCONE-A
- Synonyms
- CS-919;LICOCHALCONE-A;Licocgalcone-A;Licoricchalcone A;Licochalcone A-RM;7-Dimethoxycoumarin;Licorice Chalcone A;Licochalcone A, >99%;Licochalcone A, >=98%;Licochalcone A (10mg)
- CBNumber:
- CB5114580
- Molecular Formula:
- C21H22O4
- Molecular Weight:
- 338.4
- MDL Number:
- MFCD01417903
- MOL File:
- 58749-22-7.mol
- MSDS File:
- SDS
Melting point | 100° |
---|---|
Boiling point | 532.6±50.0 °C(Predicted) |
Density | 1.171±0.06 g/cm3(Predicted) |
storage temp. | -20°C |
solubility |
DMF:25.0(Max Conc. mg/mL);73.88(Max Conc. mM) DMSO:37.67(Max Conc. mg/mL);111.31(Max Conc. mM) Ethanol:43.5(Max Conc. mg/mL);128.54(Max Conc. mM) |
pka | 7.82±0.15(Predicted) |
form | Yellow solid |
color | Yellow-orange |
BRN | 4534154 |
InChIKey | KAZSKMJFUPEHHW-DHZHZOJOSA-N |
FDA UNII | JTV5467968 |
NCI Drug Dictionary | licochalcone A |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Warning | |||||||||
Hazard statements | H302+H312+H332 | |||||||||
Precautionary statements | P261-P264-P280-P301+P312-P302+P352+P312-P304+P340+P312 | |||||||||
Hazard Codes | Xn | |||||||||
Risk Statements | 20/21/22 | |||||||||
Safety Statements | 36/37 | |||||||||
WGK Germany | 3 | |||||||||
RTECS | UB8755000 | |||||||||
NFPA 704 |
|
LICOCHALCONE-A price More Price(35)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | PHL80486 | Licochalcone A phyproof? Reference Substance | 58749-22-7 | 10MG | $595 | 2024-03-01 | Buy |
Sigma-Aldrich | 435800 | Licochalcone-A, Synthetic | 58749-22-7 | 10mg | $111 | 2024-03-01 | Buy |
Sigma-Aldrich | 435800 | Licochalcone-A, Synthetic | 58749-22-7 | 50mg | $404 | 2024-03-01 | Buy |
Cayman Chemical | 11853 | Licochalcone A ≥95% | 58749-22-7 | 5mg | $49 | 2024-03-01 | Buy |
Cayman Chemical | 11853 | Licochalcone A ≥95% | 58749-22-7 | 10mg | $93 | 2024-03-01 | Buy |
LICOCHALCONE-A Chemical Properties,Uses,Production
Uses
Licochalcone A is an estrogenic flavonoid that induces apoptosis in multiple types of cancer cells. Licochalcone A applied to bone marrow mesenchymal stem cells (BMSC)-aggregate has strong osteogenetic differentiation thus providing a promising strategy in treating osteoporotic weight-bearing bone fractures with defects.
Definition
ChEBI: Licochalcone A is a member of chalcones.
General Description
An estrogenic flavanoid with anti-tumor and anti-parasitic properties. Shown to reduce Bcl-2 protein expression and induce apoptosis in several human cancer cell lines. Also induces cell differentiation and enhances the effect of paclitaxel and vinblastine chemotherapy. Reported to interfere with parasite mitochondrial electron transport chain and energy metabolism.
Biochem/physiol Actions
Inhibits vegetative growth of spore-forming bacteria, B. subtilis and other food-contaminating microorganisms.
LICOCHALCONE-A Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Shaanxi Cuikang Pharmaceutical Technology Co., Ltd | +8618829768577 | gao490372054@gamil.com | China | 1249 | 58 |
Shaanxi Haibo Biotechnology Co., Ltd | +undefined18602966907 | qinhe02@xaltbio.com | China | 997 | 58 |
Chongqing Zhihe Biopharmaceutical Co., Ltd. | +86-18580541567; +8618580541567 | sales@zhswyy.com | China | 303 | 58 |
Hebei Zhuanglai Chemical Trading Co Ltd | +86-16264648883 +86-16264648883 | niki@zlchemi.com | China | 1149 | 58 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21634 | 55 |
Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3619 | 58 |
Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | sales@biopurify.com | China | 3772 | 58 |
Nanjing Dolon Biotechnology Co.,Ltd. | 18905173768 | sales@dolonchem.com | CHINA | 2972 | 58 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
Shaanxi Pioneer Biotech Co., Ltd . | +8613259417953 | sales@pioneerbiotech.com | China | 3000 | 58 |
View Lastest Price from LICOCHALCONE-A manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-11-28 | Licochalcone a Powder
58749-22-7
|
US $150.00 / kg | 1kg | 99% | 500kg | Hebei Zhuanglai Chemical Trading Co Ltd | ||
2024-11-28 | Licochalcone a Powder
58749-22-7
|
US $150.00 / kg | 1kg | 99% | 500kg | Hebei Zhuanglai Chemical Trading Co Ltd | ||
2024-11-19 | Licochalcone A
58749-22-7
|
US $100.00 / mg | 98.96% | 10g | TargetMol Chemicals Inc. |
- Licochalcone a Powder
58749-22-7
- US $150.00 / kg
- 99%
- Hebei Zhuanglai Chemical Trading Co Ltd
- Licochalcone a Powder
58749-22-7
- US $150.00 / kg
- 99%
- Hebei Zhuanglai Chemical Trading Co Ltd
- Licochalcone A
58749-22-7
- US $100.00 / mg
- 98.96%
- TargetMol Chemicals Inc.
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