Amcinafide
- CAS No.
- 7332-27-6
- Chemical Name:
- Amcinafide
- Synonyms
- Amcinafide;9-Fluoro-11β,21-dihydroxy-16α,17-[[(R)-1-phenylethylidene]bis(oxy)]pregna-1,4-diene-3,20-dione
- CBNumber:
- CB51177993
- Molecular Formula:
- C29H33FO6
- Molecular Weight:
- 496.572
- MDL Number:
- MOL File:
- 7332-27-6.mol
Last updated:2022-12-21 16:56:50
| FDA UNII | F0Q1D55E29 |
|---|
Amcinafide Chemical Properties,Uses,Production
Originator
Amcinafide,Onbio Inc.
Uses
Anti-inflammatory.
Manufacturing Process
1 ml 72% perchloric acid was added to a suspension of 4 g triamcinolone in 100 ml of fresh distilled acetophenone and the mixture was stirred at a room temperature before all triamcinolone solved (for about 2 hours). The solution was neutralized with help of 8 ml of 1.1 N sodium hydroxide and sufficient quantity of sodium bicarbonate. Then chloroform and water were added. Organic layer was separated and concentrated in vacuum. The residue was recrystallized from acetone-hexane and thoroughly washed from acetophenone with hexane. Triamcinolone acetophenide (amicinafide) was prepared. It had MP: 281°-283°C (decomp.);αD 23 = +23°. (c = 0.98 in CHCl3).
Therapeutic Function
Antiinflammatory, Antiallergic
Amcinafide Preparation Products And Raw materials
Amcinafide Suppliers
Global( 1)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Lanospharma Laboratories Co.,Ltd | -- | sales@lanospharma.com | China | 6343 | 56 |
| Supplier | Advantage |
|---|---|
| Lanospharma Laboratories Co.,Ltd | 56 |
Amcinafide
9-Fluoro-11β,21-dihydroxy-16α,17-[[(R)-1-phenylethylidene]bis(oxy)]pregna-1,4-diene-3,20-dione
7332-27-6