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tirilazad

CAS No.
110101-67-2
Chemical Name:
tirilazad
Synonyms
U-74006F
CBNumber:
CB51311375
Molecular Formula:
C39H56N6O5S
Molecular Weight:
720.97
MDL Number:
MFCD00867644
MOL File:
110101-67-2.mol
Last updated:2023-05-04 17:34:31

tirilazad Properties

FDA UNII 19B418DV39

tirilazad price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
American Custom Chemicals Corporation SHG0005111 TIRILAZAD MESYLATE 95.00% 110101-67-2 5MG $550 2021-12-16 Buy
American Custom Chemicals Corporation SHG0005111 TIRILAZAD MESYLATE 95.00% 110101-67-2 1G $58327.5 2021-12-16 Buy
Product number Packaging Price Buy
SHG0005111 5MG $550 Buy
SHG0005111 1G $58327.5 Buy

tirilazad Chemical Properties,Uses,Production

Description

Tirilazad mesylate, a novel 21 -aminosteroid derivative, has been marketed in Austria for the intravenous treatment of subarachnoid hemorrhage (SAH) in male patients. Studies have indicated involvement of lipid peroxidation and/or lipid hydrolysis in the genesis of SAH-initiated microvascular damage and prolonged vasospasm of the large cerebral vessels. Tirilazad mesylate is a highly lipophilic compound that localizes to the cell membrane. It is a potent inhibitor of lipid peroxidation induced by oxygen free radicals, purely through a mechanism similar to vitamin E by scavenging lipid peroxyl radicals, and is a stabilizer of biological membranes. Tirilazad mesylate has been demonstrated to have a positive effect in reducing symptomatic vasospasm, cerebral infarction, and neurological dysfunction. Clinically, it is reportedly effective in reducing mortality in male SAH patients relative to the control group. The title compound is also reportedly in clinical trials for ischemic stroke, spinal cord injury, and for non-systemic ocular applications. Little or no behavioral and physiological side effects have been reported.

Originator

Pharmacia & Upjohn (Sweden/U.S.A.)

Definition

ChEBI: Tirilazad mesylate is a corticosteroid hormone.

brand name

Freedox

tirilazad Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 4)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354 support@targetmol.com United States 19973 58
Jinan ponder chemical co. LTD 0531-0000 thinklifescience@163.com China 19690 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24017 58
U-74006F 110101-67-2