eupatilin
- CAS No.
- 22368-21-4
- Chemical Name:
- eupatilin
- Synonyms
- eupatilin;NSC 122413;Eupatilin-RM;Eupatilin, BR;Eupatilin 22368-21-4;Eupatilin, 10 mM in DMSO;5,7-Dihydroxy-3',4',6-trimethoxyflavone;2-(3,4-Dimethoxyphenyl)-5,7-dihydroxy-6-methoxychromen-4-one;2-(3,4-Dimethoxyphenyl)-5,7-dihydroxy-6-methoxy-4H-chromen-4-one;2-(3,4-Dimethoxyphenyl)-5,7-dihydroxy-6-methoxy-4H-1-benzopyran-4-one
- CBNumber:
- CB51326292
- Molecular Formula:
- C18H16O7
- Molecular Weight:
- 344.32
- MDL Number:
- MFCD13194819
- MOL File:
- 22368-21-4.mol
| Melting point | 236-238 °C |
|---|---|
| Boiling point | 583.6±50.0 °C(Predicted) |
| Density | 1.387±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Store in freezer, under -20°C |
| solubility | Acetonitrile (Slightly), DMSO (Slightly), Methanol (Slightly, Heated) |
| form | Solid |
| pka | 6.47±0.40(Predicted) |
| color | Pale Beige |
| biological source | (Isolated from Artemisia sp.) |
| Stability | Hygroscopic |
| FDA UNII | 4D58O05490 |
| UNSPSC Code | 41116107 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319 |
| Precautionary statements | P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313 |
eupatilin price More Price(48)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | PHL80337 | Eupatilin phyproof? Reference Substance | 22368-21-4 | 10MG | $307.2 | 2024-03-01 | Buy |
| Cayman Chemical | 19601 | Eupatilin ≥98% | 22368-21-4 | 5mg | $86 | 2024-03-01 | Buy |
| Cayman Chemical | 19601 | Eupatilin ≥98% | 22368-21-4 | 10mg | $161 | 2024-03-01 | Buy |
| Cayman Chemical | 19601 | Eupatilin ≥98% | 22368-21-4 | 25mg | $379 | 2024-03-01 | Buy |
| Cayman Chemical | 19601 | Eupatilin ≥98% | 22368-21-4 | 50mg | $713 | 2024-03-01 | Buy |
eupatilin Chemical Properties,Uses,Production
Uses
Eupatilin maintains anticoagulant and antiplatelet activity isolated from the Artemisia princeps Pampanini flower.
Definition
ChEBI: A trimethoxyflavone with flavone substituted by hydroxy groups at C-5 and C-7 and methoxy groups at C-6, C-3' and C-4' respectively. Isolated from Citrus reticulata and Salvia tomentosa, it exhibits anti-inflammatory, anti-ulcer a d antineoplastic activities.
Biological Activity
Eupatilin is a flavone with anti-oxidative, anti-inflammatory, and anti-cancer properties.', 'Eupatilin is an important constituent in the leaves of Artemisia argyi and also an active component of DA-9601. It exhibits anti-apoptotic effects. Eupatilin provides protection against tumor necrosis factor α (TNF-α)-mediated inflammation in human umbilical vein endothelial cells. It is used in the treatment of gastritis and peptic ulcers. Eupatilin safeguards gastric epithelial cells from oxidative damage and smooth muscle cells from indomethacin-induced cell damage. Eupatilin lowers bile acid-stimulated hepatocyte apoptosis.
in vivo
Eupatilin (1.5% or 3.0%) restores PPARα mRNA expression, and improves atopic dermatitis (AD)-like symptoms in oxazolone-induced Balb/c mice. Eupatilin causes significant decrease in serum IgE, IL-4 levels, oxazolone-induced TNFα, IFNγ, IL-1β, TSLP, IL-33 and IL-25 mRNA expression in oxazolone-induced mice. Eupatilin also increases filaggrin and loricrin mRNA expression in oxazolone-induced mice[1].
IC 50
PPARα
storage
+4°C
eupatilin Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Zhuanglai Chemical Trading Co.,Ltd | +8613343047651 | admin@zlchemi.com | China | 3692 | 58 |
| Hebei Shengyang Water Conservancy Engineering Co., Ltd. | +8615373025980 | clara@hbshengyang.com | China | 822 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29730 | 60 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3619 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29858 | 58 |
| Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 | scglp@glp-china.com | CHINA | 1824 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +86-28-82633860; +8618080483897 | sales@biopurify.com | China | 3772 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
| NanJing Spring & Autumn Biological Engineering CO., LTD. | +8613815430202 | sale02@cqherb.com | CHINA | 376 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19552 | 58 |
View Lastest Price from eupatilin manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-04-15 | Eupatilin
22368-21-4
|
US $200.00-85.00 / kg | 1kg | 99% | 20ton | Hebei Zhuanglai Chemical Trading Co.,Ltd | |
 |
2024-11-19 | Eupatilin
22368-21-4
|
US $30.00-107.00 / mg | 99% | 10g | TargetMol Chemicals Inc. | ||
 |
2024-05-11 | Eupatilin
22368-21-4
|
US $18.00 / kg | 1kg | 99.9 | 5000 | Hebei Shengyang Water Conservancy Engineering Co., Ltd. |