- Eupatilin
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- $200.00 / 1kg
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2025-04-15
- CAS:22368-21-4
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 20ton
- Eupatilin
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- $30.00 / 1mg
-
2024-11-19
- CAS:22368-21-4
- Min. Order:
- Purity: 99%
- Supply Ability: 10g
- Eupatilin
-
- $18.00 / 10kg
-
2024-05-11
- CAS:22368-21-4
- Min. Order: 1kg
- Purity: 99.9
- Supply Ability: 5000
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| | eupatilin Basic information |
| Product Name: | eupatilin | | Synonyms: | 2-(3,4-Dimethoxyphenyl)-5,7-dihydroxy-6-methoxy-4H-1-benzopyran-4-one;5,7-Dihydroxy-3',4',6-trimethoxyflavone;2-(3,4-Dimethoxyphenyl)-5,7-dihydroxy-6-methoxychromen-4-one;4H-1-Benzopyran-4-one, 2-(3,4-diMethoxyphenyl)-5,7-dihydroxy-6-Methoxy-;eupatilin;Eupatilin
2-(3,4-Dimethoxyphenyl)-5,7-dihydroxy-6-methoxychromen-4-one;2-(3,4-Dimethoxyphenyl)-5,7-dihydroxy-6-methoxy-4H-chromen-4-one;2-(3,4-dimethoxyphenyl)-5,7-dihydroxy-6-methoxy-4H-chromen-4-one (EUPATILIN) | | CAS: | 22368-21-4 | | MF: | C18H16O7 | | MW: | 344.32 | | EINECS: | 618-347-7 | | Product Categories: | chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract | | Mol File: | 22368-21-4.mol |  |
| | eupatilin Chemical Properties |
| Melting point | 236-238 °C | | Boiling point | 583.6±50.0 °C(Predicted) | | density | 1.387±0.06 g/cm3(Predicted) | | storage temp. | Keep in dark place,Sealed in dry,Store in freezer, under -20°C | | solubility | Acetonitrile (Slightly), DMSO (Slightly), Methanol (Slightly, Heated) | | form | Solid | | pka | 6.47±0.40(Predicted) | | color | Pale Beige | | biological source | (Isolated from Artemisia sp.) | | Stability: | Hygroscopic |
| | eupatilin Usage And Synthesis |
| Uses | Eupatilin maintains anticoagulant and antiplatelet activity isolated from the Artemisia princeps Pampanini flower. | | Definition | ChEBI: A trimethoxyflavone with flavone substituted by hydroxy groups at C-5 and C-7 and methoxy groups at C-6, C-3' and C-4' respectively. Isolated from Citrus reticulata and Salvia tomentosa, it exhibits anti-inflammatory, anti-ulcer a
d antineoplastic activities. | | Biological Activity | Eupatilin is a flavone with anti-oxidative, anti-inflammatory, and anti-cancer properties.', 'Eupatilin is an important constituent in the leaves of Artemisia argyi and also an active component of DA-9601. It exhibits anti-apoptotic effects. Eupatilin provides protection against tumor necrosis factor α (TNF-α)-mediated inflammation in human umbilical vein endothelial cells. It is used in the treatment of gastritis and peptic ulcers. Eupatilin safeguards gastric epithelial cells from oxidative damage and smooth muscle cells from indomethacin-induced cell damage. Eupatilin lowers bile acid-stimulated hepatocyte apoptosis. | | in vivo | Eupatilin (1.5% or 3.0%) restores PPARα mRNA expression, and improves atopic dermatitis (AD)-like symptoms in oxazolone-induced Balb/c mice. Eupatilin causes significant decrease in serum IgE, IL-4 levels, oxazolone-induced TNFα, IFNγ, IL-1β, TSLP, IL-33 and IL-25 mRNA expression in oxazolone-induced mice. Eupatilin also increases filaggrin and loricrin mRNA expression in oxazolone-induced mice[1]. | | IC 50 | PPARα | | storage | +4°C |
| | eupatilin Preparation Products And Raw materials |
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