- Jaceosidin
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- $1000.00 / 1g
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2025-03-07
- CAS:18085-97-7
- Min. Order: 1g
- Purity: 99%
- Supply Ability: 100Tons
- Jaceosidin
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- $52.00 / 1mg
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2024-11-19
- CAS:18085-97-7
- Min. Order:
- Purity: 99.28%
- Supply Ability: 10g
- Jaceosidin
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- $0.00 / 1kg
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2023-11-01
- CAS:18085-97-7
- Min. Order: 1kg
- Purity: 98% HPLC
- Supply Ability: 500kg
Related articles - Biological Activity of Jaceosidin
- Jaceosidin, also known as 4',5,7-trihydroxy-3',6-dimethoxyflavone, is a member of the class of compounds known as 6-o-methylat....
- Oct 14，2019
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| | Jaceosidin Basic information |
| Product Name: | Jaceosidin | | Synonyms: | JACEOSIDIN;3',6-Dimethoxy-4',5,7-trihydroxyflavone;5,7-Dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-6-methoxy-4H-1-benzopyran-4-one;6-Hydroxyluteolin 3',6-dimethyl ether;Jacesiolin;4',5,7-Trihydroxy-3',6-dimethoxyflavone;4H-1-Benzopyran-4-one, 5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-6-methoxy-;5,7-dihydroxy-2-(4-hydroxy-3-methoxy-phenyl)-6-methoxy-chromen-4-one | | CAS: | 18085-97-7 | | MF: | C17H14O7 | | MW: | 330.29 | | EINECS: | | | Product Categories: | chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract | | Mol File: | 18085-97-7.mol |  |
| | Jaceosidin Chemical Properties |
| Melting point | 259-260 °C | | Boiling point | 619.0±55.0 °C(Predicted) | | density | 1.483±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C(protect from light) | | solubility | DMSO (Slightly), Methanol (Slightly, Sonicated), Pyridine (Slightly) | | form | Solid | | pka | 6.47±0.40(Predicted) | | color | Pale Yellow to Light Yellow | | Stability: | Hygroscopic | | LogP | 1.300 (est) |
| | Jaceosidin Usage And Synthesis |
| Uses | Jaceosidin exhibits anti-allergic, anti-inflammatory and apoptosis inducing activities. | | Definition | ChEBI: A trihydroxyflavone that is flavone with hydroxy groups at positions 5, 7 and 4' and methoxy groups at positions 3' and 6. Isolated from Salvia tomentosa and Artemisia asiatica, it exhibits anti-allergic, anti-inflammatory and apo
tosis inducing activties. | | in vivo | Jaceosidin (10 and 20 mg/kg, p.o., once a day for 3 days) blocks carrageenan-induced increase in leukocyte number and protein levels in air pouch exudates in mice[3].
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Jaceosidin (10, 20 mg/kg, p.o.) suppresses COX-2 expression and NF-κB activation in mice[3].
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Jaceosidin (20 mg/kg, p.o. for 2 hours) reduces hind paw edema volume in rats[3]. | Animal Model: | 5-week-old male BALB/c mice (23-26 g)[3] | | Dosage: | 10 and 20 mg/kg | | Administration: | P.O. once a day for 3 days | | Result: | Decreased the volumes of exudates (inflammatory markers), cell number and protein levels. Inhibited TNF-α by 46.7% and 50.8%, IL-1β by 46.0% and 44.7%, and PGE2 by 21.7% and 16.9%, respectively, at 20 mg/kg. Blocked COX-2 expression and NF-κB activation. |
| Animal Model: | Male Sprague-Dawley rats (180-200 g)[3] | | Dosage: | 20 mg/kg | | Administration: | P.O., for 2 hour | | Result: | Reduced hind paw edema volume by 27.1% at 1 h, and 24.0% at 2 h, respectively. |
| | IC 50 | Bax; COX-2 |
| | Jaceosidin Preparation Products And Raw materials |
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