ChemicalBook >> CAS DataBase List >>2,2,2-Trifluoroethyl trifluoromethanesulfonate
2,2,2-Trifluoroethyl trifluoromethanesulfonate
- CAS No.
- 6226-25-1
- Chemical Name:
- 2,2,2-Trifluoroethyl trifluoromethanesulfonate
- Synonyms
- 2,2,2-TRIFLUOROETHYL TRIFLUOROMETHANESULPHONATE;2,2,2-TRIFLUOROETHYL TRIFLATE;TFOL-TF;2,2,2-Trifluoroethyl Triflante;2,2,2-Trifluoroethyl trifluoromethanesulf;2-Trifluoroethyl trifluoromethanesulfonate;2,2,2-Trifluoroethyl trifluoromethanesulfote;2,2,2-Trifluoroethytrifluoromethanesulfonate;2,2,2-Trifluoroethyl trifluoroMethylsulfonate;2,2,2-TRIFLUOROETHYL TRIFLUOROMETHANESULFONATE
- CBNumber:
- CB5142808
- Molecular Formula:
- C3H2F6O3S
- Molecular Weight:
- 232.1
- MDL Number:
- MFCD00671579
- MOL File:
- 6226-25-1.mol
- MSDS File:
- SDS
Last updated:2025-04-01 13:12:09
| Boiling point | 89-91°C |
|---|---|
| Density | 1,61 g/cm3 |
| refractive index | 1.3037 |
| RTECS | PB2775000 |
| Flash point | >110°(230°F) |
| storage temp. | 2-8°C |
| solubility | Chloroform, Methanol (Slightly) |
| form | Liquid |
| color | Colorless to yellow |
| Water Solubility | Slightly soluble in water. |
| Sensitive | Moisture Sensitive |
| InChIKey | RTMMSCJWQYWMNK-UHFFFAOYSA-N |
| CAS DataBase Reference | 6226-25-1(CAS DataBase Reference) |
| EPA Substance Registry System | Methanesulfonic acid, trifluoro-, 2,2,2-trifluoroethyl ester (6226-25-1) |
| UNSPSC Code | 12352101 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301-H314-H330 | |||||||||
| Precautionary statements | P260-P270-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338 | |||||||||
| Hazard Codes | Xi,T,C | |||||||||
| Risk Statements | 36/37/38-34-23/25 | |||||||||
| Safety Statements | 26-36/37/39-45 | |||||||||
| RIDADR | 3265 | |||||||||
| WGK Germany | 3 | |||||||||
| Hazard Note | Irritant | |||||||||
| HazardClass | TOXIC, CORROSIVE | |||||||||
| HazardClass | 8 | |||||||||
| PackingGroup | Ⅱ | |||||||||
| HS Code | 29055900 | |||||||||
| NFPA 704 |
|
2,2,2-Trifluoroethyl trifluoromethanesulfonate price More Price(35)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 752924 | 2,2,2-Trifluoroethyl trifluoromethanesulfonate 95% | 6226-25-1 | 5g | $135 | 2024-03-01 | Buy |
| TCI Chemical | T1604 | 2,2,2-Trifluoroethyl Trifluoromethanesulfonate >97.0%(GC) | 6226-25-1 | 5g | $142 | 2024-03-01 | Buy |
| TCI Chemical | T1604 | 2,2,2-Trifluoroethyl Trifluoromethanesulfonate >97.0%(GC) | 6226-25-1 | 25g | $354 | 2024-03-01 | Buy |
| Alfa Aesar | H61603 | 2,2,2-Trifluoroethyl trifluoromethanesulfonate, 95% | 6226-25-1 | 5g | $128.65 | 2024-03-01 | Buy |
| Alfa Aesar | H61603 | 2,2,2-Trifluoroethyl trifluoromethanesulfonate, 95% | 6226-25-1 | 25g | $462.65 | 2024-03-01 | Buy |
2,2,2-Trifluoroethyl trifluoromethanesulfonate Chemical Properties,Uses,Production
Uses
A fluorine-containing alkyl alkanesulfonate with cyctotoxity towards cultured leukemia L1210 cells.
Uses
2,2,2-Trifluoroethyl trifluoromethanesulfonate is a powerful trifluoroethylating agent which is useful for synthesis of fluorinated amino acids. It is used as a reagent in thenantioselective preparation of cyclic N-aryl hydroxamic acids via phase-transfer catalyzed alkylation of nitrobenzyl bromides to give nirophenylalanines.
Uses
Reagent used in thenantioselective preparation of cyclic N-aryl hydroxamic acids via phase-transfer catalyzed alkylation of nitrobenzyl bromides to give nirophenylalanines
Synthesis
In a 100-ml flask equipped with a stirrer, a thermometer, a nitrogen introducing pipe, and a condenser, 50 ml (0.297 mol) of trifluoromethane sulfonic anhydride and 25 ml (0.342 moles) of 2,2,2-trifluoroethanol were placed at room temperature and stirred for 30 minutes in a nitrogen atmosphere, followed by reflux for 3 hours. After distillation, 50.3 g of 2,2,2-trifluoroethyl trifluoromethanesulfonate was obtained in a yield of 73%.
Synthesis of 2,2,2-Trifluoroethyl trifluoromethanesulfonate from 2,2,2-Trifluoroethanol and Trifluoromethanesulfonyl bromide
2,2,2-Trifluoroethyl trifluoromethanesulfonate Preparation Products And Raw materials
Raw materials
Preparation Products
2,2,2-Trifluoroethanol
2,2,3,3,3-Pentafluoropropyl 2,2,2-trifluoroethyl carbonate
4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-1-(2,2,2-trifluoroethyl)-1H-pyrazole
TFEC
tert-butyl (1-(2,2,2-trifluoroethyl)piperidin-4-yl)carbaMate
4-NITRO-1-(2,2,2-TRIFLUOROETHYL)-1H-PYRAZOLE
ethyl 1-(2,2,2-trifluoroethyl)piperidine-4-carboxylate
3-Methyl-5-(2,2,2-trifluoroethoxy)picolinonitrile
2H-1-BENZAZEPIN-2-ONE 6-FLUORO-1,3,4,5-TETRAHYDRO-3-[4-[3-METHOXY-4-(4-METHYL-1H-IMIDAZOL-1-YL)PHENYL]-1H-1,2,3-TRIAZOL-1-YL]-1-(2,2,2-TRIFLUOROETHYL)-
(5-(2,2,2-trifluoroethoxy)pyridin-2-yl)methanol
1of3
Global( 324)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| JIANGXI TIME PHARMACEUTICAL CO.,LTD | +86-0794-7183888 +86-13155888520 | sales@groupchem.com | China | 27 | 58 |
| Henan Aochuang Chemical Co.,Ltd. | +86-0371-63689365 +8618638391208 | sales@aochuangchem.com | China | 9297 | 58 |
| Hebei Zhuanglai Chemical Trading Co Ltd | +86-16264648883 +86-16264648883 | niki@zlchemi.com | China | 7245 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29730 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-+86-371-66670886 | info@dakenam.com | China | 19841 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21628 | 55 |
| Shanghai Time Chemicals CO., Ltd. | +86-021-57951555 +8617317452075 | jack.li@time-chemicals.com | China | 1803 | 55 |
| Fluoropharm Co., Ltd. | +86-0571-85586753 +86-13336034509 | sales@fluoropharm.com | China | 1445 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Zjartschem | +86-571 87238903 | jocelynpan@zjarts.com | CHINA | 988 | 58 |
View Lastest Price from 2,2,2-Trifluoroethyl trifluoromethanesulfonate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-04-29 | 2,2,2-Trifluoroethyl trifluoromethanesulfonate
6226-25-1
|
US $10.00 / kg | 1kg | 99% | 20 ton | Hebei Zhuanglai Chemical Trading Co Ltd | |
 |
2025-04-04 | 2,2,2-Trifluoroethyl trifluoromethanesulfonate
6226-25-1
|
US $0.00-0.00 / kg | 1kg | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. | |
 |
2023-03-10 | 2,2,2-Trifluoroethyl trifluoromethanesulfonate
6226-25-1
|
US $0.00 / KG | 1KG | 99.0% | 1000KG | LY Global chemicals co.,ltd . |
-
- 2,2,2-Trifluoroethyl trifluoromethanesulfonate
6226-25-1
- US $10.00 / kg
- 99%
- Hebei Zhuanglai Chemical Trading Co Ltd
-
- 2,2,2-Trifluoroethyl trifluoromethanesulfonate
6226-25-1
- US $0.00-0.00 / kg
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-
- 2,2,2-Trifluoroethyl trifluoromethanesulfonate
6226-25-1
- US $0.00 / KG
- 99.0%
- LY Global chemicals co.,ltd .
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TFOL-TF
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High purity CAS 6226-25-1 2,2,2-Trifluoroethyl trifluoromethanesulfonate in stock
2,2,2-TRIFLUOROETHYL TRIFLATE
2,2,2-TRIFLUOROETHYL TRIFLUOROMETHANESULPHONATE
2,2,2-TRIFLUOROETHYL TRIFLATE
2,2,2-Trifluoroethyl Trifluoromethanesulfonate
2,2,2-Trifluoroethyl Triflante
2,2,2-Trifluoroethyl trifluoromethanesulf
6226-25-1
56226-25-1
C3H2F6O3S
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