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3-bromo-1H-indazole-7-carbonitrile

CAS No.
945762-00-5
Chemical Name:
3-bromo-1H-indazole-7-carbonitrile
Synonyms
nNOS-IN-1;INOS-IN-14;3-bromo-7-cyano-1H-indazole;3-bromo-1H-indazole-7-carbonitrile;1H-INDAZOLE-7-CARBONITRILE, 3-BROMO-
CBNumber:
CB51558743
Molecular Formula:
C8H4BrN3
Molecular Weight:
222.04
MDL Number:
MFCD11848409
MOL File:
945762-00-5.mol
Last updated:2025-04-18 09:51:09

3-bromo-1H-indazole-7-carbonitrile Properties

Boiling point 425.3±25.0 °C(Predicted)
Density 1.85±0.1 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
pka 8.69±0.40(Predicted)
form Solid
color Off-white to light brown

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

3-bromo-1H-indazole-7-carbonitrile price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
American Custom Chemicals Corporation HCH0044878 3-BROMO-1H-INDAZOLE-7-CARBONITRILE 95.00% 945762-00-5 5MG $503.88 2021-12-16 Buy
AK Scientific Y4808 3-Bromo-1H-indazole-7-carbonitrile 945762-00-5 250mg $346 2021-12-16 Buy
AK Scientific Y4808 3-Bromo-1H-indazole-7-carbonitrile 945762-00-5 5g $1466 2021-12-16 Buy
Crysdot CD11006469 3-Bromo-1H-indazole-7-carbonitrile 95+% 945762-00-5 5g $347 2021-12-16 Buy
Ambeed A366631 3-Bromo-1H-indazole-7-carbonitrile 95% 945762-00-5 1g $410 2021-12-16 Buy
Product number Packaging Price Buy
HCH0044878 5MG $503.88 Buy
Y4808 250mg $346 Buy
Y4808 5g $1466 Buy
CD11006469 5g $347 Buy
A366631 1g $410 Buy

3-bromo-1H-indazole-7-carbonitrile Chemical Properties,Uses,Production

Uses

nNOS-IN-1(Compound 14) is an inhibitor for nitric oxide synthases (NOS), that exhibits inhibitory activities against neuroal, inducible and endothelial NOS, with IC50s of 2.5, 5.7 and 13 μM, respectively[1].

IC 50

nNOS: 2.5 μM (IC50); iNOS: 5.7 μM (IC50); eNOS: 13 μM (IC50)

References

[1] Cottyn B, et al., Inhibitory effects of a series of 7-substituted-indazoles toward nitric oxide synthases: particular potency of 1H-indazole-7-carbonitrile. Bioorg Med Chem. 2008 Jun 1;16(11):5962-73. DOI:10.1016/j.bmc.2008.04.056

256228-64-5
945762-00-5
Synthesis of 3-bromo-1H-indazole-7-carbonitrile from 1H-INDAZOLE-7-CARBONITRILE

3-bromo-1H-indazole-7-carbonitrile Preparation Products And Raw materials

3-bromo-1H-indazole-7-carbonitrile Suppliers

Global( 34)Suppliers
Supplier Tel Email Country ProdList Advantage
Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63687 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32239 58
Aladdin Scientific
tp@aladdinsci.com United States 52924 58
Amadis Chemical Company Limited
571-89925085 sales@amadischem.com China 131957 58
NovoChemy Ltd. 021-31261262/ 49 (0)17662837245 sales@novochemy.com Germany 6328 58
Shanghai potentpharm CO.,Ltd 13524892556 sales-cn@potentpharm.com China 1011 55
ShangHai AmK Pharmaceutical Technology Co., Ltd. 18019252918 sale@amkchem.com China 15297 55
Shanghai HuanChuan Industry Co.,Ltd. 021-61478794 sales@hcshhai.com China 9793 50
Shenzhen Gre-syn Chemical Technology Co., Ltd. 0755-0755-89366401 18617066401 hangbingfang@163.com China 898 55
Shanghai Synchem Pharma Co., ltd 21-619849051-1 18521059765 synchempharma@aliyun.com China 6466 55

View Lastest Price from 3-bromo-1H-indazole-7-carbonitrile manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
iNOS-IN-14 pictures 2024-11-19 iNOS-IN-14
945762-00-5
US $34.00 / mg 99.68% 10g TargetMol Chemicals Inc.
  • iNOS-IN-14 pictures
  • iNOS-IN-14
    945762-00-5
  • US $34.00 / mg
  • 99.68%
  • TargetMol Chemicals Inc.
3-bromo-1H-indazole-7-carbonitrile 1H-INDAZOLE-7-CARBONITRILE, 3-BROMO- 3-bromo-7-cyano-1H-indazole INOS-IN-14 nNOS-IN-1 945762-00-5