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BZ-TYR-4-ABZ-OH

BZ-TYR-4-ABZ-OH structure

CAS No.: 37106-97-1

Chemical Name:: BZ-TYR-4-ABZ-OH

Synonyms: btpaba;chymex;e-2663;BTPABA,PFT;BENTIROMIDE;BZ-TYR-4-ABZ-OH;BentiroMide, BTPABA;benzoyltyrosyl-p-aminobenzoicacid;N-Benzoyl-L-tyrosyl-p-aminobenzoate;n-benzoyl-l-tyrosyl-p-aminobenzoicacid

CBNumber:: CB5161221

Molecular Formula:: C23H20N2O5

Molecular Weight:: 404.42

MDL Number:: MFCD00055768

MOL File:: 37106-97-1.mol

MSDS File:: SDS

Last updated:2024-11-19 23:02:33

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BZ-TYR-4-ABZ-OH Properties

Melting point	240-242°
alpha	D25 +72.3° (c = 1 in DMF) (US 3801562); D25 +87° (c = 1 in DMF) (De Benneville)
Boiling point	526.04°C (rough estimate)
Density	1.3093 (rough estimate)
refractive index	1.6300 (estimate)
storage temp.	Store at RT.
solubility	DMSO:250.0(Max Conc. mg/mL);618.17(Max Conc. mM)
form	Solid
pka	4.27±0.10(Predicted)
color	White to off-white
FDA UNII	239IF5W61J
ATC code	V04CK03

BZ-TYR-4-ABZ-OH price More Price(12)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Usbiological	265226	Bz-Tyr-4-Abz-OH	37106-97-1	500mg	$213	2021-12-16	Buy
Biosynth Carbosynth	FB49255	Bz-Tyr-4-Abz-OH	37106-97-1	1g	$250	2021-12-16	Buy
Biosynth Carbosynth	FB49255	Bz-Tyr-4-Abz-OH	37106-97-1	2g	$400	2021-12-16	Buy
American Custom Chemicals Corporation	PEP0004601	BENTIROMIDE 95.00%	37106-97-1	5MG	$403.5	2021-12-16	Buy
American Custom Chemicals Corporation	PEP0004601	BENTIROMIDE 95.00%	37106-97-1	250MG	$570	2021-12-16	Buy

Product number	Packaging	Price	Buy
265226	500mg	$213	Buy
FB49255	1g	$250	Buy
FB49255	2g	$400	Buy
PEP0004601	5MG	$403.5	Buy
PEP0004601	250MG	$570	Buy

BZ-TYR-4-ABZ-OH Chemical Properties,Uses,Production

Originator

PFD Oral Sol,Eisai,Japan,1980

Uses

Diagnostic aid (pancreas function determination).

Definition

ChEBI: The dipeptide obtained by condensation of N-benzoyl-L-tyrosine with 4-aminobenzoic acid. Used as a noninvasive screening test for exocrine pancreatic insufficiency and to monitor the adequacy of supplemental pancreatic t erapy, it is given by mouth: the amount of 4-aminobenzoic acid and its metabolites excreted in the urine is taken as a measure of the chymotrypsin-secreting activity of the pancreas.

Manufacturing Process

A mixture was made of L-tyrosine (18.1 g, 0.1 mol) benzoyl chloride (7.0 g, 0.05 mol) and 200 ml anhydrous THF. After stirring at reflux for 2 hours, the mixture was cooled to room temperature, and the precipitate of tyrosine hydrochloride filtered off (11 g, 46 meq. Cl-). The THF was evaporated and the residue extracted with CCl4 (3 X 100 ml at reflux, discarded) and then dissolved in ethyl acetate (200 ml) filtering off insolubles. The ethyl acetate solution was evaporated to yield 132 g solid product, MP 159°-162°C (93%). The tyrosine was recovered (8 g) by neutralization with aqueous alkali, from the hydrochloride.
A solution was made of N-benzyl-L-tyrosine (5.7 g, 20 mmols) and Nmethylmorpholine (2.04 g, 20 mmols) in 60 ml of THF, at -15°C, and to it was added ethyl chloroformate (2.08 g, 20 mmols). After 12 minutes, paminobenzoic acid (2.74 g, 20 mmols) dissolved in 25 ml of THF and 0.38 g of p-toluenesulfonic acid (2 mmols) were added, and the temperature allowed to rise to 5°C. After 2 hours and forty minutes, the mixture was poured into l liter of 0.1 N cold HCl, stirred one-half hour, filtered and dried, to give 8,7 g, MP 192°-223°C. The product was recrystallized from 90 ml methanol and 40 ml water, to give 6 g (74%) of product, N-benzoyl-L-tyrosyl-p-aminobenzoic acid, MP 240°-242°C.

brand name

Chymex (Savage).

Therapeutic Function

Diagnostic aid (pancreatic function)

BZ-TYR-4-ABZ-OH Preparation Products And Raw materials

Raw materials

4-Aminobenzoic acid Sodium chloride 4-Methylmorpholine

Preparation Products

BZ-TYR-4-ABZ-OH Suppliers

Global( 55)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hangzhou FandaChem Co.,Ltd.	+8615858145714	FandaChem@Gmail.com	China	9210	55
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32165	58
BOC Sciences	16314854226; +16314854226	inquiry@bocsci.com	United States	19741	58
Dayang Chem (Hangzhou) Co.,Ltd.	571-88938639 +8617705817739	info@dycnchem.com	China	52849	58
Chengdu Youngshe Chemical Co., Ltd.	+8618108235634	Cecilia@youngshechem.com	China	2345	58
TargetMol Chemicals Inc.		support@targetmol.com	United States	38632	58
GIHI CHEMICALS CO.,LIMITED	+8618058761490	info@gihichemicals.com	China	49979	58
Nanjing TGpeptide	+86-13347807150 +86-13347807150	support@tgpeptide.com	China	3279	58
Zhejiang Hangyu API Co., Ltd	+8617531972939	anna@api-made.com	China	2943	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	52925	58

Supplier	Advantage
Hangzhou FandaChem Co.,Ltd.	55
TargetMol Chemicals Inc.	58
BOC Sciences	58
Dayang Chem (Hangzhou) Co.,Ltd.	58
Chengdu Youngshe Chemical Co., Ltd.	58
TargetMol Chemicals Inc.	58
GIHI CHEMICALS CO.,LIMITED	58
Nanjing TGpeptide	58
Zhejiang Hangyu API Co., Ltd	58
Aladdin Scientific	58

View Lastest Price from BZ-TYR-4-ABZ-OH manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2024-11-19	Bentiromide 37106-97-1	US $42.00-95.00 / mg		100%	10g	TargetMol Chemicals Inc.
	2024-11-19	Bentiromide 37106-97-1	US $42.00-95.00 / mg		100%	10g	TargetMol Chemicals Inc.

Bentiromide
37106-97-1
US $42.00-95.00 / mg
100%
TargetMol Chemicals Inc.

Bentiromide
37106-97-1
US $42.00-95.00 / mg
100%
TargetMol Chemicals Inc.

37106-97-1(BZ-TYR-4-ABZ-OH)Related Search:

PANCREATIC POLYPEPTIDE (RANA TEMPORARIA) Secretin (human) CHEMBRDG-BB 9071855 BZ-PHE-NH2 4-(BUTYLAMINO)BENZOIC ACID

AC-TYR-NHME BZ-TYR-4-ABZ-OH 4-Acetamidobenzaldehyde BZ-TYR-NH2 BZ-TYR-4-ABZ-OH SODIUM SALT,BZ-TYR-4-ABZ-OH NA SALT,BENTIROMIDE,bentiromide sodium,Bentiromide, N-Benzoyl-L-tyrosyl-4-aminobenzoic acid sodium salt

p-Acetylamino benzoic acid 4-(propionylamino)benzoic acid AC-TYR-NH2

1of3

4-[[(S)-2-(Benzoylamino)-3-(4-hydroxyphenyl)-1-oxopropyl]amino]benzoic acid BTPABA,PFT (s)-4-((2-(benzoylamino)-3-(4-hydroxyphenyl)-1-oxopropyl)amino)benzoicacid (s)-p-(alpha-benzamido-p-hydroxyhydrocinnamamido)benzoicacid 4-((2-(benzoylamino)-3-(4-hydroxyphenyl)-1-oxopropyl)amino)-benzoicaci(s) 4-((2-(benzoylamino)-3-(4-hydroxyphenyl)-1-oxopropyl)amino)benzoicacid benzoyltyrosyl-p-aminobenzoicacid BentiroMide, BTPABA BZ-TYR-4-ABZ-OH BENTIROMIDE btpaba chymex e-2663 n-benzoyl-l-tyrosyl-p-aminobenzoicacid p-((n-benzoyl-l-tyrosin)amido)benzoicacid 4-(N-Benzoyl-L-tyrosyl)aminobenzoic acid Benzoic acid, 4-[[(2S)-2-(benzoylamino)-3-(4-hydroxyphenyl)-1-oxopropyl]amino]- Benzoic acid, 4-[[2-(benzoylamino)-3-(4-hydroxyphenyl)-1-oxopropyl]amino]-, (S)- N-Benzoyl-L-tyrosyl-p-aminobenzoate (S)-4-(2-Benzamido-3-(4-hydroxyphenyl)propanamido)benzoic acid 37106-97-1 C23H20N2O5