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Difloxacin

CAS No.
98106-17-3
Chemical Name:
Difloxacin
Synonyms
a56619;DIFLOXACIN;Difloxacin USP/EP/BP;-1-piperazinyl)-4-oxo-;DIFLOXACINHCL/MESYLATE;Acrylamide Impurity 32;Difloxacin in Methanol/DMSO;Difloxacin Hydrochloride Salt;3-quinolinecarboxylicacid,1,4-dihydro-6-fluoro-1-(4-fluorophenyl)-7-(4-methyl;6-fluoro-1-(4-fluorophenyl)-7-(4-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylicaci
CBNumber:
CB5175282
Molecular Formula:
C21H19F2N3O3
Molecular Weight:
399.39
MDL Number:
MFCD00865975
MOL File:
98106-17-3.mol
MSDS File:
SDS
Last updated:2024-11-19 23:02:33

Difloxacin Properties

Melting point 279-282 °C(Solv: chloroform (67-66-3); ethanol (64-17-5))
Boiling point 595.5±50.0 °C(Predicted)
Density 1.409±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO (Slightly), Methanol (Slightly), Water (Slightly)
form Solid
pka 6.17±0.41(Predicted)
color White to Pale Yellow
CAS DataBase Reference 98106-17-3(CAS DataBase Reference)
FDA UNII 5Z7OO9FNFD

SAFETY

Risk and Safety Statements

Difloxacin price More Price(14)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 272206 Difloxacin hydrochloride salt 98106-17-3 50mg $405 2021-12-16 Buy
AK Scientific V2078 Difloxacin 98106-17-3 250mg $407 2021-12-16 Buy
Biorbyt Ltd orb593389 Difloxacin 98106-17-3 50μg $425 2021-12-16 Buy
Matrix Scientific 098810 6-Fluoro-1-(4-fluorophenyl)-7-(4-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid 95+% 98106-17-3 1g $588 2021-12-16 Buy
American Custom Chemicals Corporation API0002350 DIFLOXACIN 95.00% 98106-17-3 1G $630 2021-12-16 Buy
Product number Packaging Price Buy
272206 50mg $405 Buy
V2078 250mg $407 Buy
orb593389 50μg $425 Buy
098810 1g $588 Buy
API0002350 1G $630 Buy

Difloxacin Chemical Properties,Uses,Production

Description

Difloxacin (INN) is a second-generation, synthetic fluoroquinolone antibiotic used in veterinary medicine,it has broad-spectrum, concentration dependent, bactericidal activity; however, its efficacy is not as good as enrofloxacin or pradofloxacin.

Mechanism of action

Difloxacin mainly acts on bacterial deoxyribonucleic acid (DNA) helicase, inhibiting DNA replication and transcription, thereby affecting the normal shape and function of DNA to achieve bactericidal purposes. 

Physical properties

Whtie-Cream to Yellowish Crystalline Powder

Uses

Difloxacin is a fluoroquinolone antibacterial structurally related to norfloxacin.

Definition

ChEBI: A quinolone that is pefloxacin in which the ethyl group at position 1 of the quinolone has been replaced by a p-fluorophenyl group. A broad-spectrum antibiotic effective against both Gram-positive and Gram-negative bacteria, it is used (usuall as the monohydrochloride salt) for the treatment of bacterial infections in dogs.

704-10-9
98106-17-3
Synthesis of Difloxacin from 2,4-Dichloro-5-fluoroacetophenone

Difloxacin Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 87)Suppliers
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CONIER CHEM AND PHARMA LIMITED
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Career Henan Chemica Co
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TargetMol Chemicals Inc.
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Wuhan Topule Biopharmaceutical Co., Ltd
+8618327326525 masar@topule.com China 8467 58
Henan Fengda Chemical Co., Ltd
+86-371-86557731 +86-13613820652 info@fdachem.com China 20286 58
TargetMol Chemicals Inc.
+8613564774135 zijue.cai@tsbiochem.com United States 19885 58

View Lastest Price from Difloxacin manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Difloxacin HCl pictures 2024-11-19 Difloxacin HCl
98106-17-3
US $1980.00-2500.00 / mg 10g TargetMol Chemicals Inc.
Difloxacin USP/EP/BP pictures 2021-07-20 Difloxacin USP/EP/BP
98106-17-3
US $1.10 / g 1g 99.9% 100 Tons Min Dideu Industries Group Limited
  • Difloxacin HCl pictures
  • Difloxacin HCl
    98106-17-3
  • US $1980.00-2500.00 / mg
  • TargetMol Chemicals Inc.
DIFLOXACIN -1-piperazinyl)-4-oxo- 3-quinolinecarboxylicacid,1,4-dihydro-6-fluoro-1-(4-fluorophenyl)-7-(4-methyl a56619 6-Fluoro-1-(4-fluorophenyl)-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic Acid Hydrochloride Salt Difloxacin Hydrochloride Salt 6-Fluoro-1-(4-fluorophenyl)-7-(4-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid DIFLOXACINHCL/MESYLATE 6-Fluoro-1-(4-fluorophenyl)-7-(4-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic 6-Fluoro-1-(4-fluorophenyl)-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid 6-Fluoro-1-(4-fluorophenyl)-1,4-dihydro-7-(4-methylpiperazin-1-yl)-4-oxo-3-quinolinecarboxylic acid 6-Fluoro-1-(4-fluorophenyl)-7-(4-methyl-1-piperazinyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid 6-Fluoro-1-(4-fluorophenyl)-7-(4-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic ac 6-Fluoro-1-(4-fluorophenyl)-7-(4-Methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid Difloxacin USP/EP/BP 6-fluoro-1-(4-fluorophenyl)-7-(4-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylicaci 3-Quinolinecarboxylic acid, 6-fluoro-1-(4-fluorophenyl)-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo- Difloxacin in Methanol/DMSO Acrylamide Impurity 32 98106-17-3 C21H20ClF2N3O3 C21H19F2N3O3 Inhibitors Intermediates & Fine Chemicals Pharmaceuticals Chiral Reagents