ChemicalBook >> CAS DataBase List >>Cinchonidine
Cinchonidine
- CAS No.
- 485-71-2
- Chemical Name:
- Cinchonidine
- Synonyms
- (-)-CINCHONIDINE;(-)-Cinchonidine;Cinchondine;(8s,9r)-cinchonidine;(8a,9R)-Cinchonan-9-ol;L-Cin;A-QUINIDINE;Cinchovatine;CINCHONIDINE;2'-Hydroxy-4'
- CBNumber:
- CB5246395
- Molecular Formula:
- C19H22N2O
- Molecular Weight:
- 294.39
- MDL Number:
- MFCD00006783
- MOL File:
- 485-71-2.mol
Last updated:2023-08-30 13:35:17
Melting point | 204-206 °C(lit.) |
---|---|
alpha | -115 º (c=1, EtOH) |
Boiling point | 436.16°C (rough estimate) |
Density | 1.0863 (rough estimate) |
vapor pressure | 0Pa at 25℃ |
refractive index | -107.5 ° (C=1, EtOH) |
storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
solubility | 0.25g/l |
form | Crystalline Powder |
pka | 5.80, 10.03(at 25℃) |
color | White to cream |
PH | 9 (0.2g/l, H2O, 20℃) |
optical activity | [α]23/D 109.2°, c = 1.5 in ethanol |
Water Solubility | Insoluble |
Sensitive | Light Sensitive |
Merck | 14,2286 |
BRN | 89690 |
Stability | Stable, but light-sensitive. Incompatible with strong oxidizing agents. |
InChIKey | KMPWYEUPVWOPIM-NAHPKXJFSA-N |
LogP | 2.68 at 25℃ |
CAS DataBase Reference | 485-71-2(CAS DataBase Reference) |
EWG's Food Scores | 1 |
FDA UNII | 1U622LRA8Z |
NIST Chemistry Reference | Cinchonidine(485-71-2) |
EPA Substance Registry System | Cinchonan-9-ol, (8.alpha.,9R)- (485-71-2) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
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Signal word | Warning | |||||||||
Hazard statements | H302-H317-H319 | |||||||||
Precautionary statements | P261-P264-P280-P301+P312-P302+P352-P305+P351+P338 | |||||||||
Hazard Codes | Xn,Xi | |||||||||
Risk Statements | 20/21/22-42/43-36/37/38-20/22-48/22-43-22-63 | |||||||||
Safety Statements | 22-24/25-36/37-36-26 | |||||||||
RIDADR | 1544 | |||||||||
WGK Germany | 3 | |||||||||
RTECS | GD2975000 | |||||||||
TSCA | Yes | |||||||||
HazardClass | 6.1(b) | |||||||||
PackingGroup | III | |||||||||
HS Code | 29392900 | |||||||||
Toxicity | LD50 i.p. in rats: 206 mg/kg (Johnson, Poe); LD50 orally in quail: >316 mg/kg (Schafer) | |||||||||
NFPA 704 |
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Cinchonidine price More Price(35)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | C80407 | Cinchonidine 96% | 485-71-2 | 10g | $38.4 | 2024-03-01 | Buy |
Sigma-Aldrich | PHL80961 | (-)-Cinchonidine phyproof? Reference Substance | 485-71-2 | 100mg | $262 | 2024-03-01 | Buy |
Sigma-Aldrich | C80407 | Cinchonidine 96% | 485-71-2 | 100g | $138 | 2024-03-01 | Buy |
Sigma-Aldrich | 44703 | (−)-Cinchonidine analyticalstandard | 485-71-2 | 100mg | $45.9 | 2021-12-16 | Buy |
TCI Chemical | C0347 | Cinchonidine >98.0%(T) | 485-71-2 | 25g | $73 | 2024-03-01 | Buy |
Cinchonidine Chemical Properties,Uses,Production
Chemical Properties
white to light yellow crystal powde
Uses
antiamebic, antiprotozoal
Uses
Cinchonidine occurs in most varieties of Cinchona bark and is stereoisomeric with Cinchonine. Cinchonidine exhibits Antimalarial properties.
Definition
ChEBI: 8-epi-Cinchonan in which a hydrogen at position 9 is substituted by hydroxy (R configuration). A diasteroisomer of cinchonine, it occurs in the bark of most varieties of Cinchona shrubs, and is frequently used for directing chirality in asymmetric synthesis.
Flammability and Explosibility
Non flammable
Purification Methods
Crystallise cinchonidine from aqueous EtOH. For the N-benzylcinchonidinium chloride see above entry in this section. [Beilstein 23 III/IV 2824.]
Cinchonidine Preparation Products And Raw materials
Raw materials
Preparation Products
Esfenvalerate
1,1'-Bis (di-t-butylphosphino)ferrocene palladium dichloride,
(S)-(-)-7,7'-BIS[DI(3,5-DIMETHYLPHENYL)PHOSPHINO]-2,2',3,3'-TETRAHYDRO-1,1'-SPIROBIINDANE
Fosinopril
1,1'-SPIROBIINDANE-7,7'-DIOL
1of3
Global( 397)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Guangzhou TongYi biochemistry technology Co.,LTD | +8613073028829 | mack@tongyon.com | China | 2996 | 58 |
Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12450 | 58 |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 16914 | 58 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21668 | 55 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32760 | 60 |
Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3620 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29894 | 58 |
SHANDONG ZHI SHANG CHEMICAL CO.LTD | +86 18953170293 | sales@sdzschem.com | China | 2931 | 58 |
Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 | alice@crovellbio.com | China | 8822 | 58 |
Shaanxi Pioneer Biotech Co., Ltd . | +8613259417953 | sales@pioneerbiotech.com | China | 3000 | 58 |
View Lastest Price from Cinchonidine manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
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2024-08-20 | Cinchonidine
485-71-2
|
US $371.00 / KG | 1KG | 99% | 100kg | Baoji Guokang Bio-Technology Co., Ltd. | |
![]() |
2023-08-30 | Cinchonidine
485-71-2
|
US $0.00 / KG | 1KG | 99% | 50000KG/month | Hebei Mojin Biotechnology Co., Ltd | |
![]() |
2022-05-11 | Cinchonidine
485-71-2
|
US $0.00 / g | 10g | 99.0% | 10tons | Wuhan Godbullraw Chemical Co.,ltd |
-
- Cinchonidine
485-71-2
- US $371.00 / KG
- 99%
- Baoji Guokang Bio-Technology Co., Ltd.
-
- Cinchonidine
485-71-2
- US $0.00 / KG
- 99%
- Hebei Mojin Biotechnology Co., Ltd
-
- Cinchonidine
485-71-2
- US $0.00 / g
- 99.0%
- Wuhan Godbullraw Chemical Co.,ltd
485-71-2(Cinchonidine)Related Search:
1of4
(8-alpha,9r)-cinchonan-9-o
(8alpha,9theta)-cinchonan-9-o
2-Quinuclidinemethanol, alpha-4-quinolyl-5-vinyl-
Cinchonan-9-ol
Cinchonan-9-ol, (8alpha,9R)-
Cinchovatine
Cinchonidinederivedcatalyst
{5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl}(quinolin-4-yl)Methanol
Cinchonidine, 98.5-101% 100GR
Cinchonidine, 98.5-101% 25GR
CINCHONIDINE
1-Cinchonidine
(-)-Cinchonidine (total base), may cont. up to 5% quinine
cinchonidine .base
Cinchonidine ,98.5%
Cinchonidine,()-Cinchonidine
(-)-CINCHONIDINE FOR RESOLUTION OF RACEM
(-)-Cinchonidine, 99%, may contain up to 5% quinine
(-)-Cinchonidine for resolution of racemates for synthesis
CINCHONAN-9-OL,(8,9R)-
A-QUINIDINE
ALPHA-QUINIDINE
(8alpha,9r)-cinchonan-9-ol
CINCHONIDINE: CINCHONAN-9-OL,(8,9R)-,
Cinchonidine,99%
[8α,9R]-Cinchonan-9-ol
Cinchonidine, 98.5-101%
CINCHONIDINE(RG)
L-CINCHONIDINE
Cinchonidine (base and/or unspecified salts)
4-Quinolyl-(5-vinyl-1-azabicyclo[2.2.2]oct-2-yl)methanol
(R)-Quinolin-4-yl[(2S,4S,5R)-5-vinyl-1-azabicyclo[2.2.2]oct-2-yl]methanol
(8S,9R)-Cinchonan-9-ol
(-)-Cinchonidine, 99% (total base), may cont. up to 5% quinine
(R)-[(4S,5R,7S)-5-Ethenyl-1-azabicyclo[2.2.2]octan-7-yl]-quinolin-4-ylmethanol
(R)-[(2S,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl](quinolin-4-yl)methanol
(3alpha,4beta,8alpha,9S)-cinchonan-9-ol
(3alpha,9R)-9-hydroxycinchonan-1-ium
(4beta,8alpha,9R)-cinchonan-1-ium-9-ol
(8alpha,9R)-9-hydroxycinchonan-1-ium
(9R)-cinchonan-1-ium-9-ol
(9R)-cinchonan-9-ol
Quinine Sulphate EP Impurity B
L-Cin
Cinchonidine, 98%, for synthesis
Cinchonidine >
Quinine EP Impurity B
(R)-Quinolin-4-yl((1S,2S,4S,5R)-5-vinylquinuclidin-2-yl)methanol
Cinchonidine USP/EP/BP
[(2R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-quinolin-4-ylmethanol
2'-Hydroxy-4'
(8s,9r)-cinchonidine
Cinchondine
(-)-CINCHONIDINE
(-)-Cinchonidine
(8a,9R)-Cinchonan-9-ol
Cinchonidine (8CI)
(R)-[(2S,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]oct-2-yl](quinolin-4-yl)methanol (cinchonidine)