4-Methoxystyrene
- CAS No.
- 637-69-4
- Chemical Name:
- 4-Methoxystyrene
- Synonyms
- 4-VINYLANISOLE;P-METHOXYSTYRENE;vinylanisole;4-Vinylanisol;p-Vinylanisole;4-METHOXYSTYRENE;p-Anisylethylene;Anisole, p-vinyl-;PARA-METHOXYSTYRENE;4-Methoxystyrene,98%
- CBNumber:
- CB5246416
- Molecular Formula:
- C9H10O
- Molecular Weight:
- 134.18
- MDL Number:
- MFCD00008619
- MOL File:
- 637-69-4.mol
- MSDS File:
- SDS
| Melting point | 2°C |
|---|---|
| Boiling point | 41-42 °C/0.5 mmHg (lit.) |
| Density | 1.009 g/mL at 25 °C (lit.) |
| refractive index |
n |
| Flash point | 170 °F |
| storage temp. | Store at <= 20°C. |
| solubility | Slightly miscible with methanol. |
| form | Liquid |
| Specific Gravity | 1.009 |
| color | Clear colorless to yellow |
| Odor | sweet |
| BRN | 1098935 |
| LogP | 2.874 (est) |
| CAS DataBase Reference | 637-69-4(CAS DataBase Reference) |
| FDA UNII | 2ISH8T4A6E |
| NIST Chemistry Reference | Benzene, 1-ethenyl-4-methoxy-(637-69-4) |
| EPA Substance Registry System | Benzene, 1-ethenyl-4-methoxy- (637-69-4) |
| UNSPSC Code | 12352112 |
| NACRES | NA.23 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H227-H315-H319 | |||||||||
| Precautionary statements | P210e-P280a-P370+P378a-P501a-P210-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P370+P378-P403+P235-P501 | |||||||||
| Safety Statements | 23-24/25 | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 29093090 | |||||||||
| NFPA 704 |
|
4-Methoxystyrene price More Price(34)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 141003 | 4-Vinylanisole 97% | 637-69-4 | 5g | $143 | 2024-03-01 | Buy |
| Sigma-Aldrich | 141003 | 4-Vinylanisole 97% | 637-69-4 | 25g | $239.4 | 2024-03-01 | Buy |
| TCI Chemical | M0130 | 4-Methoxystyrene (stabilized with TBC) >98.0%(GC) | 637-69-4 | 10mL | $99 | 2024-03-01 | Buy |
| TCI Chemical | M0130 | 4-Methoxystyrene (stabilized with TBC) >98.0%(GC) | 637-69-4 | 25mL | $198 | 2024-03-01 | Buy |
| Alfa Aesar | B22353 | 4-Methoxystyrene, 98%, stab. with 0.1% 4-tert-butylcatechol | 637-69-4 | 5g | $69.6 | 2024-03-01 | Buy |
4-Methoxystyrene Chemical Properties,Uses,Production
Description
4-Methoxystyrene (Para-methoxystyrene) is an important chemical raw material, can replace styrene compounds, and is widely applied to various fields such as a light polymerization inhibitor, a material, a medical intermediate, a pesticide, an adhesive, a coating, a sun-screening agent and the like. Besides, the p-methoxystyrene can be used as a polymerization monomer to synthesize polymers with different structures, and the synthesized polymer contains a protecting group which is easily subjected to acidolysis by light so that the p-methoxystyrene can be used as an excellent corrosion-resistant material to be applied to the electronic information industry.
Chemical Properties
CLEAR COLOURLESS LIQUID
Uses
4-Methoxystyrene is employed in the ferric chloride-catalyzed addition of activated methylenes to styrenes. It acts as a monomer in polymerization reactions. Further, it is used to prepare 1,1,2,2-Tetracyano-3-(p-methoxyphenyl)cyclobutane by reacting with ethenetetracarbonitrile.
Synthesis Reference(s)
Chemistry Letters, 13, p. 1897, 1984
The Journal of Organic Chemistry, 52, p. 422, 1987 DOI: 10.1021/jo00379a020
Tetrahedron Letters, 35, p. 8773, 1994 DOI: 10.1016/S0040-4039(00)78494-2
Synthesis
The current methods for synthesizing 4-Methoxystyrene mainly comprise:
P-methoxy styrene is prepared by taking p-methoxy benzyl alcohol as a raw material and reacting with triphenylphosphine, formaldehyde and hydrobromic acid through the Wittig reaction.
P-methoxyacetophenone is used as a raw material, reduced to 1- (4-methoxyphenyl) ethanol by potassium borohydride, esterified with excessive potassium bisulfate in cyclohexane to generate sulfonic acid-1- (4-methoxyphenyl) ethyl ester, and finally subjected to elimination reaction to obtain 4-Methoxystyrene.
In 2021, an invention discloses a method for synthesizing 4-methoxystyrene, which comprises the steps of using p-methoxyacetophenone as a raw material, firstly carrying out hydrogenation reduction to generate 1- (4-methoxyphenyl) ethanol, then carrying out dehydration elimination reaction to obtain a crude product, and finally rectifying to obtain the 4-methoxystyrene. The invention adopts a catalytic hydrogenation method to get the intermediate 1- (4-methoxyphenyl) ethanol. The reaction selectivity of the step is excellent and can reach 98-99%, and meanwhile, hydrogen is used as a cleaning gas so that environmental pollution is avoided and industrial production is facilitated.
4-Methoxystyrene Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39927 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20233 | 58 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-+86-371-66670886 | info@dakenam.com | China | 19843 | 58 |
| Nanjing Finetech Chemical Co., Ltd. | 025-85710122 17714198479 | sales@fine-chemtech.com | CHINA | 885 | 55 |
| Anqing Chico Pharmaceutical Co., Ltd. | 15380796838 | chloewu@chicopharm.cn | CHINA | 340 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29858 | 58 |
| Xiamen AmoyChem Co., Ltd | +86-86-5926051114 +8615060885618 | sales@amoychem.com | China | 6383 | 58 |
| Xiamen Shindano Biotechnology Co.,ltd | 0592-6266840 15750707980 | sales@chemsdano.com | China | 291 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49732 | 58 |
View Lastest Price from 4-Methoxystyrene manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-04-25 | 4-Methoxystyrene
637-69-4
|
US $0.00-0.00 / kg | 1kg | 99%+ | 1000000kg per Month | Shanghai Qyubiotech Co., Ltd. | |
 |
2025-04-24 | 4-Methoxystyrene
637-69-4
|
US $200.00 / KG | 1KG | 0.98 | 20 tons | Chongqing Chemdad Co., Ltd | |
 |
2023-12-26 | 4-Methoxystyrene
637-69-4
|
US $100.00-1.00 / KG | 1KG | 99% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd |
-
- 4-Methoxystyrene
637-69-4
- US $0.00-0.00 / kg
- 99%+
- Shanghai Qyubiotech Co., Ltd.
-
- 4-Methoxystyrene
637-69-4
- US $200.00 / KG
- 0.98
- Chongqing Chemdad Co., Ltd
-
- 4-Methoxystyrene
637-69-4
- US $100.00-1.00 / KG
- 99%
- Henan Fengda Chemical Co., Ltd