ChemicalBook >> CAS DataBase List >>5,6-Dichloronicotinic acid

5,6-Dichloronicotinic acid

CAS No.
41667-95-2
Chemical Name:
5,6-Dichloronicotinic acid
Synonyms
2,3-dichloropyridine-5-carboxylic acid;5,6-DichL;5,6-Dichloro;TIMTEC-BB SBB003623;Avatrhopal Impurity 45;5,6-DICHLORONICOTINIC A;Avatrombopag Impurity 10;Avatroposide impurities16;5,6-DICHLORONICOTINIC ACID;5,6-DichloronicotinicAcid>
CBNumber:
CB5261891
Molecular Formula:
C6H3Cl2NO2
Molecular Weight:
192
MDL Number:
MFCD00075181
MOL File:
41667-95-2.mol
MSDS File:
SDS
Last updated:2024-11-26 11:58:42

5,6-Dichloronicotinic acid Properties

Melting point 164-168 °C(lit.)
Boiling point 342.1±37.0 °C(Predicted)
Density 1.612±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility DMSO (Slightly), Methanol (Slightly)
pka 2.87±0.10(Predicted)
form Powder
color White to beige to tan
BRN 383740
InChI InChI=1S/C6H3Cl2NO2/c7-4-1-3(6(10)11)2-9-5(4)8/h1-2H,(H,10,11)
InChIKey RNRLTTNKVLFZJS-UHFFFAOYSA-N
SMILES C1=NC(Cl)=C(Cl)C=C1C(O)=O
CAS DataBase Reference 41667-95-2(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P301+P312+P330
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  22-24/25-36-26
WGK Germany  3
HazardClass  IRRITANT
HS Code  29339900
NFPA 704
1
2 0

5,6-Dichloronicotinic acid price More Price(40)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 340219 5,6-Dichloropyridine-3-carboxylic acid 96% 41667-95-2 5g $26 2023-06-20 Buy
TCI Chemical D2401 5,6-Dichloronicotinic Acid >98.0%(T) 41667-95-2 5g $56 2024-03-01 Buy
TCI Chemical D2401 5,6-Dichloronicotinic Acid >98.0%(T) 41667-95-2 25g $191 2024-03-01 Buy
Alfa Aesar B25586 5,6-Dichloronicotinic acid, 98+% 41667-95-2 25g $209 2021-12-16 Buy
Alfa Aesar B25586 5,6-Dichloronicotinic acid, 98+% 41667-95-2 5g $62.7 2021-12-16 Buy
Product number Packaging Price Buy
340219 5g $26 Buy
D2401 5g $56 Buy
D2401 25g $191 Buy
B25586 25g $209 Buy
B25586 5g $62.7 Buy

5,6-Dichloronicotinic acid Chemical Properties,Uses,Production

Chemical Properties

white to off-white crystalline powder

Uses

5,6-Dichloronicotinic acid is a dihalonicotinic acid. It is used in the preparation of 5-chloro-6-iodonicotinic acid by iodine displacement.

Application

5,6-Dichloronicotinic acid is a compound that can be synthesized by reacting methyl ketones with chloroacetic acid. It is used in the synthesis of maleic anhydride and has been shown to inhibit the catalysis of acetylcholine chloride. It has also been shown to have an inhibitory effect on Alzheimer's disease. The kinetic mechanism for this inhibition occurs through the hydrolysis step of 5,6-Dichloronicotinic acid by magnesium chloride in hexane solution. The reactive acylation reaction proceeds when it reacts with acetic anhydride in the presence of pyridine.

401566-69-6
41667-95-2
Synthesis of 5,6-Dichloronicotinic acid from 5,6-DICHLORONICOTINIC ACID ETHYL ESTER
Global( 417)Suppliers
Supplier Tel Email Country ProdList Advantage
Changzhou Ditong Chemical Co.,Ltd
+86-0519-88299272 info@edengenechem.com China 2158 58
Senova Technology Co. Ltd.
+86-0755-86703119 +8618503098836 info@senovatech.com China 351 58
Shenyang TYSChem Co., Ltd.
+86-24-83607930 +8618640359690 sales@honghuchem.com China 403 58
Jinan Dexinjia Bio&Tech Co., Ltd
+86-0531-82375893 +86-15064117275 sales@jndxj.com China 1267 58
Hebei Weibang Biotechnology Co., Ltd
+8615531157085 abby@weibangbio.com China 8810 58
Hebei Yanxi Chemical Co., Ltd.
+8617531190177 peter@yan-xi.com China 5857 58
Henan Fengda Chemical Co., Ltd
+86-371-86557731 +86-13613820652 info@fdachem.com China 20284 58
Frapp's ChemicalNFTZ Co., Ltd.
+86 (576) 8169-6106 sales@frappschem.com China 880 50
Capot Chemical Co.,Ltd.
+86-(0)57185586718 +86-13336195806 sales@capot.com China 29791 60
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21634 55

View Lastest Price from 5,6-Dichloronicotinic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
5,6-Dichloronicotinic acid pictures 2024-12-23 5,6-Dichloronicotinic acid
41667-95-2
US $0.00-0.00 / kg 1kg ≥98% by HPLC 50kg/month Zison Pharmaceutical (Shandong) Co., Ltd.
5,6-Dichloronicotinic acid pictures 2024-11-26 5,6-Dichloronicotinic acid
41667-95-2
US $10.00 / KG 1KG 99% 10 mt Hebei Weibang Biotechnology Co., Ltd
5,6-Dichloronicotinic acid pictures 2024-10-25 5,6-Dichloronicotinic acid
41667-95-2
US $0.00 / kg 1kg 0.99 20 tons Hebei Yanxi Chemical Co., Ltd.
5,6-DICHLORO-3-PYRIDINECARBOXYLIC ACID 5,6-DICHLORONICOTINIC ACID 5,6-DICHLOROPYRIDINE-3-CARBOXYLIC ACID TIMTEC-BB SBB003623 5,6-Dichloropyridine-3-carboxylicacid,96% 5,6-Dichloro 5,6-DICHLORONICOTINIC ACID 98+% 5,6-Dichloronicotinic acid, 5,6-Dichloropyridine-3-carboxylic acid 5,6-Dichloropyridine-3-carboxylic acid, 98+% 5,6-Dichloropyridine-3-carboxylic acid, 5-Carboxy-2,3-dichloropyridine 5,6-Dichloronicotinic acid 97% 5,6-DichloronicotinicAcid> 5,6-DichL 3-Pyridinecarboxylic acid, 5,6-dichloro- Avatrombopag Impurity 10 5,6-Dichloronicotinic acid ISO 9001:2015 REACH 5,6-DICHLORONICOTINIC A 2,3-dichloropyridine-5-carboxylic acid Avatroposide impurities16 (4-cyclohexylpiperazin-1-yl)(5,6-dichloropyridin-3-yl)methanone Avatrhopal Impurity 45 41667-95-2 1667-95-2 Pyridines Heterocyclic Building Blocks Halogenated Heterocycles Building Blocks Chloropyridines Halopyridines Heterocycle-Pyridine series Chloropyridines Halopyridines Pyridine Building Blocks C5 to C6 C6 to C7 Chemical Synthesis Halogenated Heterocycles Heterocyclic Building Blocks Pyridines pharmacetical Organic acids Pyridines, Pyrimidines, Purines and Pteredines Intermediate