ChemicalBook >> CAS DataBase List >>BroMosporine
BroMosporine
- CAS No.
- 1619994-69-2
- Chemical Name:
- BroMosporine
- Synonyms
- CS-921;BroMosporine;BroMosporine USP/EP/BP;KASUMI-1,HIV,AIDS,Human immunodeficiency virus,MV4;N-[6-(3-Methanesulfonamido-4-methylphenyl)-3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-8-yl]carbamate;ethyl 3-Methyl-6-(4-Methyl-3-(MethylsulfonaMido)phenyl)-[1,2,4]triazolo[4,3-b]pyridazin-8-ylcarbaMate;Carbamic acid, N-[3-methyl-6-[4-methyl-3-[(methylsulfonyl)amino]phenyl]-1,2,4-triazolo[4,3-b]pyridazin-8-yl]-, ethyl ester;11,Bromosporine,inhibit,AML,colorectal cancer,CDK,antitumor,T cells,HCT116,Apoptosis,HT29,anticancer,Epigenetic Reader Domain,Inhibitor,Cyclin dependent kinase
- CBNumber:
- CB52676961
- Molecular Formula:
- C17H20N6O4S
- Molecular Weight:
- 404.44
- MDL Number:
- MFCD26142669
- MOL File:
- 1619994-69-2.mol
- MSDS File:
- SDS
Last updated:2023-09-04 15:51:00
Density | 1.46±0.1 g/cm3(Predicted) |
---|---|
storage temp. | Sealed in dry,Store in freezer, under -20°C |
solubility | Soluble in DMSO (up to 25 mg/ml) |
form | solid |
pka | 6.21±0.46(Predicted) |
color | Off-white |
Stability | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months. |
BroMosporine price More Price(24)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Cayman Chemical | 14119 | Bromosporine ≥98% | 1619994-69-2 | 1mg | $37 | 2024-03-01 | Buy |
Cayman Chemical | 14119 | Bromosporine ≥98% | 1619994-69-2 | 5mg | $108 | 2024-03-01 | Buy |
Cayman Chemical | 14119 | Bromosporine ≥98% | 1619994-69-2 | 10mg | $195 | 2024-03-01 | Buy |
Cayman Chemical | 14119 | Bromosporine ≥98% | 1619994-69-2 | 25mg | $353 | 2024-03-01 | Buy |
Tocris | 4758 | Bromosporine ≥98%(HPLC) | 1619994-69-2 | 10 | $287 | 2021-12-16 | Buy |
BroMosporine Chemical Properties,Uses,Production
Description
Bromosporine (1619994-69-2) is a potent pan-Bromodomain (BRD) inhibitor.1?Bromosporine was able to reactivate HIV-1 replication in different latency models.2
Uses
Bromosporine is a broad spectrum inhibitor for bromodomains.
target
bromodomain
storage
Store at +4°C
References
1) Picaud?et al.?(2016),?Promiscuous targeting of bromodomains by bromosporine identifies BET proteins as master regulators of primary transcription response in leukemia; Sci. Adv.?2?e1600760 2) Pan?et al.?(2017),?The bromodomain and extraterminal domain inhibitor bromosporine synergistically reactivates latent HIV-1 in latently infected cells; Oncotarget?8?94104
BroMosporine Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 84)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29888 | 58 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39916 | 58 |
HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6313 | 58 |
Changzhou Xuanming Pharmaceutical Technology Co., Ltd. | +8615995072465 | sales@xuanmingchem.com | China | 906 | 58 |
Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 23499 | 58 |
Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10522 | 58 |
InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | trendseenbio@gmail.com | China | 11681 | 58 |
View Lastest Price from BroMosporine manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2019-07-06 | BroMosporine
1619994-69-2
|
US $1.00 / KG | 1G | 98% | 100KG | Career Henan Chemical Co |
- BroMosporine
1619994-69-2
- US $1.00 / KG
- 98%
- Career Henan Chemical Co
BroMosporine
ethyl 3-Methyl-6-(4-Methyl-3-(MethylsulfonaMido)phenyl)-[1,2,4]triazolo[4,3-b]pyridazin-8-ylcarbaMate
N-[6-(3-Methanesulfonamido-4-methylphenyl)-3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-8-yl]carbamate
CS-921
Carbamic acid, N-[3-methyl-6-[4-methyl-3-[(methylsulfonyl)amino]phenyl]-1,2,4-triazolo[4,3-b]pyridazin-8-yl]-, ethyl ester
BroMosporine USP/EP/BP
11,Bromosporine,inhibit,AML,colorectal cancer,CDK,antitumor,T cells,HCT116,Apoptosis,HT29,anticancer,Epigenetic Reader Domain,Inhibitor,Cyclin dependent kinase
KASUMI-1,HIV,AIDS,Human immunodeficiency virus,MV4
1619994-69-2
Inhibitors
API