di(Atorvastatin-d5) CalciuM Salt
- CAS No.
- 222412-82-0
- Chemical Name:
- di(Atorvastatin-d5) CalciuM Salt
- Synonyms
- [2H5]-Atorvastatin Calcium;Atorvastatin calcium salt-[d5];di(Atorvastatin-d5) CalciuM Salt;Atorvastatin D5 calciumQ: What is Atorvastatin D5 calcium Q: What is the CAS Number of Atorvastatin D5 calcium Q: What is the storage condition of Atorvastatin D5 calcium Q: What are the applications of Atorvastatin D5 calcium
- CBNumber:
- CB52708842
- Molecular Formula:
- C132H122Ca3D10F4N8O20-2
- Molecular Weight:
- 2356.79131058
- MDL Number:
- MOL File:
- 222412-82-0.mol
di(Atorvastatin-d5) CalciuM Salt price More Price(5)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 25043 | Atorvastatin-d5 (calcium salt) ≥99% deuterated forms (d1 -d3) | 222412-82-0 | 500μg | $178 | 2024-03-01 | Buy |
| Cayman Chemical | 25043 | Atorvastatin-d5 (calcium salt) ≥99% deuterated forms (d1 -d3) | 222412-82-0 | 1mg | $336 | 2024-03-01 | Buy |
| TRC | A791754 | Atorvastatin-d5CalciumSalt | 222412-82-0 | 0.5mg | $175 | 2021-12-16 | Buy |
| Medical Isotopes, Inc. | D49605 | di(Atorvastatin-d5)CalciumSalt | 222412-82-0 | 1mg | $640 | 2021-12-16 | Buy |
| Medical Isotopes, Inc. | D49605 | di(Atorvastatin-d5)CalciumSalt | 222412-82-0 | 10mg | $2120 | 2021-12-16 | Buy |
di(Atorvastatin-d5) CalciuM Salt Chemical Properties,Uses,Production
Uses
di(Atorvastatin-d5) Calcium Salt is the labeled analogue of Atorvastatin Calcium Salt (A791750), a selective, competitive HMG-CoA reductase . Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglyceinhibitorrides in patients with hypercholesterolemia.
Biological Activity
Atorvastatin-d5 is intended for use as an internal standard for the quantification of atorvastatin by GC- or LC-MS. Atorvastatin is an inhibitor of HMG-CoA reductase, the rate-limiting enzyme in the mevalonate pathway of cholesterol synthesis, that has IC50 values of 73, 102, and 0.6 nM for HepG2 cells, human fibroblasts, and rat hepatocytes, respectively.1 Formulations containing atorvastatin have been used in the treatment of hypercholesterolemia and certain dyslipidemias.
References
1.Shaw, M.K., Newton, R.S., Sliskovic, D.R., et al.Hep-G2 cells and primary rat hepatocytes differ in their response to inhibitors of HMG-CoA reductaseBiochem. Biophys. Res. Commun.170(2)726-734(1990)
di(Atorvastatin-d5) CalciuM Salt Preparation Products And Raw materials
Raw materials
Preparation Products
di(Atorvastatin-d5) CalciuM Salt Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Standardpharm Co. Ltd. | 86-714-3992388 | overseasales1@yongstandards.com | United States | 14336 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32344 | 50 |
| Cato Research Chemicals Inc. | 020-81960175 | min.he@cato-chem.com | China | 1958 | 55 |
| ChemStrong Scientific Co.,Ltd | 0755-0755-66853366 13670046396 | sales@chem-strong.com | China | 18018 | 56 |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 13028896684 | sales@rrkchem.com | China | 56060 | 58 |
| Guangzhou Dreampharm Biotechnology Co., Ltd. | 020-36607679 17825480238 | 3008233717@qq.com | China | 9896 | 12 |
| Jinan blalong chemical co. LTD | 2710913286@.com | 1513643261@qq.com | China | 14253 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing1@energy-chemical.com | China | 44843 | 58 |
| Guangzhou Juntang Technology Co., Ltd | 020-36607679 13502246435 | sales@dmstandards.com | China | 10951 | 58 |
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