| Company Name: |
J & K SCIENTIFIC LTD.
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| Tel: |
010-82848833 400-666-7788 |
| Email: |
jkinfo@jkchemical.com |
| Products Intro: |
Product Name:di(Atorvastatin-d5) CalciuM Salt
CAS:222412-82-0
Package:10Mg,1Mg
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| Company Name: |
Cato Research Chemicals Inc.
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| Tel: |
020-81960175 |
| Email: |
min.he@cato-chem.com |
| Products Intro: |
Product Name:di(Atorvastatin-d5) CalciuM Salt
CAS:222412-82-0
Purity:95% Package:25Mg, 50Mg
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di(Atorvastatin-d5) CalciuM Salt manufacturers
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| | di(Atorvastatin-d5) CalciuM Salt Basic information |
| Product Name: | di(Atorvastatin-d5) CalciuM Salt | | Synonyms: | di(Atorvastatin-d5) CalciuM Salt;[2H5]-Atorvastatin Calcium;Atorvastatin calcium salt-[d5];Atorvastatin D5 calciumQ: What is
Atorvastatin D5 calcium Q: What is the CAS Number of
Atorvastatin D5 calcium Q: What is the storage condition of
Atorvastatin D5 calcium Q: What are the applications of
Atorvastatin D5 calcium | | CAS: | 222412-82-0 | | MF: | C132H122Ca3D10F4N8O20-2 | | MW: | 2356.79131058 | | EINECS: | | | Product Categories: | | | Mol File: | 222412-82-0.mol |  |
| | di(Atorvastatin-d5) CalciuM Salt Chemical Properties |
| storage temp. | Store at -20°C | | solubility | DMF: 25 mg/ml,DMSO: 15 mg/ml,Ethanol: 0.50 mg/ml | | form | A solid | | color | White to off-white |
| | di(Atorvastatin-d5) CalciuM Salt Usage And Synthesis |
| Uses | di(Atorvastatin-d5) Calcium Salt is the labeled analogue of Atorvastatin Calcium Salt (A791750), a selective, competitive HMG-CoA reductase . Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglyceinhibitorrides in patients with hypercholesterolemia. | | Biological Activity | Atorvastatin-d5 is intended for use as an internal standard for the quantification of atorvastatin by GC- or LC-MS. Atorvastatin is an inhibitor of HMG-CoA reductase, the rate-limiting enzyme in the mevalonate pathway of cholesterol synthesis, that has IC50 values of 73, 102, and 0.6 nM for HepG2 cells, human fibroblasts, and rat hepatocytes, respectively.1 Formulations containing atorvastatin have been used in the treatment of hypercholesterolemia and certain dyslipidemias. | | References | 1.Shaw, M.K., Newton, R.S., Sliskovic, D.R., et al.Hep-G2 cells and primary rat hepatocytes differ in their response to inhibitors of HMG-CoA reductaseBiochem. Biophys. Res. Commun.170(2)726-734(1990) |
| | di(Atorvastatin-d5) CalciuM Salt Preparation Products And Raw materials |
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