Choline glycerophosphate
- CAS No.
- 28319-77-9
- Chemical Name:
- Choline glycerophosphate
- Synonyms
- Alpha GPC;GPC;CHOLINE ALFOSCERATE;glycerophosphocholine;SN-GLYCERO-3-PHOSPHOCHOLINE;GLYCEROPHOSPHORYLCHOLINE;L-ALPHA-GLYCERYLPHOSPHORYLCHOLINE;Alpha GPC powder;L-α-glycerylphosphorylcholine;L-α-Glycerophosphorylcholine
- CBNumber:
- CB5309777
- Molecular Formula:
- C8H20NO6P
- Molecular Weight:
- 257.22
- MDL Number:
- MFCD00063544
- MOL File:
- 28319-77-9.mol
Melting point | 142.5-143° |
---|---|
alpha | D25 -2.7° (c = 2.7 in water, pH 2.5); D25 -2.8° (c = 2.6 in water, pH 5.8) |
Boiling point | 480℃[at 101 325 Pa] |
vapor pressure | 0Pa at 25℃ |
Flash point | 11 °C |
storage temp. | -20°C |
solubility | DMSO (Slightly, Heated, Sonicated), Methanol (Sparingly), Water (Sparingly) |
form | solid |
color | White to Off-White |
Water Solubility | 1000g/L at 25℃ |
Stability | Very Hygroscopic |
InChI | InChI=1/C8H20NO6P/c1-9(2,3)4-5-14-16(12,13)15-7-8(11)6-10/h8,10-11H,4-7H2,1-3H3/t8-/s3 |
InChIKey | SUHOQUVVVLNYQR-SBYBRXNCNA-N |
SMILES | P([O-])(=O)(OCC[N+](C)(C)C)OC[C@H](O)CO |&1:12,r| |
LogP | -5.15 at 25℃ |
CAS DataBase Reference | 28319-77-9(CAS DataBase Reference) |
EWG's Food Scores | 1 |
FDA UNII | 60M22SGW66 |
ATC code | N07AX02 |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H315-H319-H335-H412 |
Precautionary statements | P261-P273-P305+P351+P338 |
Hazard Codes | F,T |
Risk Statements | 11-23/24/25-39/23/24/25 |
Safety Statements | 16-36/37-45-24/25 |
RIDADR | UN 1230 3/PG 2 |
WGK Germany | 2 |
RTECS | KH2775000 |
HS Code | 29239000 |
Choline glycerophosphate price More Price(35)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | G5291 | L-α-Glycerophosphorylcholine from soybean, ≥98%, powder | 28319-77-9 | 50mg | $184 | 2024-03-01 | Buy |
Sigma-Aldrich | G5291 | L-α-Glycerophosphorylcholine from soybean, ≥98%, powder | 28319-77-9 | 100mg | $318 | 2024-03-01 | Buy |
Cayman Chemical | 20736 | sn-glycero-3-Phosphocholine ≥95% | 28319-77-9 | 1g | $44 | 2024-03-01 | Buy |
Cayman Chemical | 20736 | sn-glycero-3-Phosphocholine ≥95% | 28319-77-9 | 5g | $109 | 2024-03-01 | Buy |
Sigma-Aldrich | G5291 | L-α-Glycerophosphorylcholine from soybean, ≥98%, powder | 28319-77-9 | 10mg | $63.8 | 2024-03-01 | Buy |
Choline glycerophosphate Chemical Properties,Uses,Production
Description
Choline alfoscerate is a nootropic reportedly effective in the treatment of age-associated memory impairment. In man, it decreased and prevented scopolamine-induced amnesia. In vitro studies suggest that choline alfoscerate acts indirectly on cholinergic transmission by elevating the synthesis of acetylcholine.
Chemical Properties
Choline glycerophosphate (GPC) is a white waxy solid that is miscible with water, soluble in methanol and ethanol, and insoluble in chloroform, ether, oil, etc. It has no characteristic absorption under UV visible light. The methods for determining GPC content include high-performance liquid chromatography (equipped with an evaporative light scattering detector or refractive index differential detector) and the digestion phosphorus determination method.
Originator
Sandoz; Italfarmaco (Italy)
Uses
sn-Glycero-3-phosphocholine (Choline Alfoscerate) is a phospholipid; precursor in choline biosynthesis. sn-Glycero-3-phosphocholine is an intermediate in catabolic pathway of phosphatidylcholine. sn-Glycero-3-phosphocholine is used as an Nootropic.
Uses
L-α-Glycerophosphorylcholine has been used to rescue choline auxotrophy. It has also been used for the synthesis of glycerophospholipids.
Definition
ChEBI: Choline alfoscerate is a member of the class of phosphocholines that is the choline ester of sn-glycero-3-phosphate. It is one of the major osmolyte in the renal medullary cells. It has a role as a parasympatholytic, a neuroprotective agent, a human metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite and a mouse metabolite. It is a member of sn-glycerol 3-phosphates and a member of phosphocholines.
brand name
Delecit
General Description
L-α-Glycerophosphorylcholine is a phospholipid, which is a derivative of phosphatidylcholine.
Flammability and Explosibility
Not classified
Biochem/physiol Actions
Increases inositol phosphate formation.
Choline glycerophosphate Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
TIANJIN KANGCHAO BIO-PHARMACEUTICAL TECH CO.,LTD | +8613164071169 | kangchao1208@126.com | China | 1 | 58 |
Wuhan Fortuna Chemical Co., Ltd | +86-027-59207850 | info@fortunachem.com | China | 5989 | 58 |
Jinan Jianfeng Chemical Co., Ltd | +8615562555968 | info@pharmachemm.com | China | 243 | 58 |
Wuhan senwayer century chemical Co.,Ltd | +undefined-27-86652399 +undefined13627115097 | market02@senwayer.com | China | 894 | 58 |
Shaanxi LonierHerb Bio Technology Co Ltd | +86-86-+86-86-029-87551862 +8617702909819 | sales006@ingredients-lonier.com | China | 2605 | 58 |
Mascot I.E.Co .,Ltd. | +86-0519-85010339 +8613584504415 | info@mascotchem.com | China | 309 | 58 |
BINBO BIOLOGICAL CO.,LTD | +8618629063126 | info@binbobiological.com | China | 346 | 58 |
Leading Chemical and Trading Co.,Ltd | +8615669938129 | sales@leadingchemical.com | China | 130 | 58 |
Dorne Chemical Technology co. LTD | +86-86-13583358881 +8618560316533 | Ethan@dornechem.com | China | 3145 | 58 |
Hebei Guanlang Biotechnology Co,.LTD | +8619930503252 | daisy@crovellbio.com | China | 5828 | 58 |
View Lastest Price from Choline glycerophosphate manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
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2024-08-24 | Alpha GPC
28319-77-9
|
US $1.00-9.90 / g | 1g | 99% | 100kg | Wuhan Cell Pharmaceutical Co., Ltd | |
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2024-08-24 | Choline glycerophosphate
28319-77-9
|
US $1.00 / g | 1g | 99% | 1000kg | Dorne Chemical Technology co. LTD | |
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2024-08-24 | Alpha-GPC Chonile Alfoscerate
28319-77-9
|
US $20.00 / kg | 1kg | 99.9% | 10000 | Hebei Miaoyin Technology Co.,Ltd |
-
- Alpha GPC
28319-77-9
- US $1.00-9.90 / g
- 99%
- Wuhan Cell Pharmaceutical Co., Ltd
-
- Choline glycerophosphate
28319-77-9
- US $1.00 / g
- 99%
- Dorne Chemical Technology co. LTD
-
- Alpha-GPC Chonile Alfoscerate
28319-77-9
- US $20.00 / kg
- 99.9%
- Hebei Miaoyin Technology Co.,Ltd