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2,3,5,6-TETRACHLOROPHENOL

CAS No.
935-95-5
Chemical Name:
2,3,5,6-TETRACHLOROPHENOL
Synonyms
NSC 407823;2,3,5,6-TCP;2,3,5,6-TECP;2.3.5.6-Tetr;Fourchlorophenol;2,3,5,6-tetrachloro-pheno;2,3,5,6-Tetrachloropheno1;2,3,5,6-TETRACHLOROPHENOL;2,3,5,6-tetrachlorophenate;phenol,2,3,5,6-tetrachloro
CBNumber:
CB5311769
Molecular Formula:
C6H2Cl4O
Molecular Weight:
231.89
MDL Number:
MFCD00044671
MOL File:
935-95-5.mol
Last updated:2023-05-15 10:43:03

2,3,5,6-TETRACHLOROPHENOL Properties

Melting point 115-116℃ (isooctane )
Boiling point 331.59°C (rough estimate)
Density 1.6 g/cm3 (60℃)
refractive index 1.5133 (estimate)
Flash point 11 °C
storage temp. APPROX 4°C
solubility Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
pka 5.09±0.20(Predicted)
Water Solubility 0.1g/L(25 ºC)
BRN 2049586
CAS DataBase Reference 935-95-5(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII SW5F2W8SDJ
EPA Substance Registry System 2,3,5,6-Tetrachlorophenol (935-95-5)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS06,GHS09
Signal word  Danger
Hazard statements  H301-H335-H410
Precautionary statements  P273-P301+P310+P330
Hazard Codes  T,F
Risk Statements  25-37/38-41-39/23/24/25-23/24/25-11
Safety Statements  26-39-45-36/37-16
RIDADR  UN 2020 6.1/PG 3
WGK Germany  3
RTECS  SM9450000

2,3,5,6-TETRACHLOROPHENOL price More Price(5)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 442284 2,3,5,6-Tetrachlorophenol analytical standard 935-95-5 50mg $90.1 2024-03-01 Buy
Sigma-Aldrich 36518 2,3,5,6-Tetrachlorophenol PESTANAL 935-95-5 10mg $70.1 2022-05-15 Buy
Sigma-Aldrich 442284 2,3,5,6-Tetrachlorophenol analytical standard 935-95-5 442284 $68.2 2021-12-16 Buy
TRC T292285 2,3,5,6-Tetrachlorophenol 935-95-5 5mg $70 2021-12-16 Buy
American Custom Chemicals Corporation HCH0010578 2,3,5,6-TETRACHLOROPHENOL UNLABELED 95.00% 935-95-5 50MG $764.03 2021-12-16 Buy
Product number Packaging Price Buy
442284 50mg $90.1 Buy
36518 10mg $70.1 Buy
442284 442284 $68.2 Buy
T292285 5mg $70 Buy
HCH0010578 50MG $764.03 Buy

2,3,5,6-TETRACHLOROPHENOL Chemical Properties,Uses,Production

Chemical Properties

Brown solid; phenol odor. Soluble in sodium hydroxide solutions and most organic solvents; insoluble in water.

Uses

Fungicide, wood preservative.

Production Methods

Chlorophenols are generally prepared by the chlorination of phenol. There are other routes of synthesis as through diazotizing p-chloroaniline or dechlorinating (by alkaline hydrolysis) 1,2,4,5-tetrachlorobenzene to yield 2,4,5-trichlorophenol (TCP). Polychlorinated dibenzo-p-dioxins can be formedduringthemanufacturingprocess of the chlorophenols. The amount formed depends on temperature and pressure process variability during production. The more notable toxic dioxin, 2,3,7,8-tetrachlorodibenzo-p-dioxin (2,3,7,8-TCDD), is formed during the production of 2,4,5- TCP. Laboratory reference standards of 2,3,7,8-TCDD are prepared by heating 2,4,5-TCP under alkaline conditions. All technical and formulated products containing 2,4,5-TCP are expected to be contaminated to varying degrees by this 2,3,7,8-TCDD by-product of the manufacturing process.

Definition

ChEBI: The 2,3,5,6-isomer of tetrachlorophenol

General Description

Leaflets (from ligroin) or light beige powder.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

2,3,5,6-TETRACHLOROPHENOL is incompatible with acid chlorides, acid anhydrides and oxidizing agents. .

Hazard

Toxic by ingestion and inhalation, strong irritant.

Fire Hazard

Flash point data for 2,3,5,6-TETRACHLOROPHENOL are not available. 2,3,5,6-TETRACHLOROPHENOL is probably combustible.

Carcinogenicity

There was no evidence of carcinogenic activity of 2,4-dichlorophenol in F344/N rats or B6C3F1 mice from the NTP bioassay program, but 2,4,6-trichlorophenol was reported to be carcinogenic in both species.

Purification Methods

Crystallise the phenol from pet ethers. The benzoate has m 136o (from EtOH). [Beilstein 6 II 182, 6 III 730, 6 IV 1025.]

118-75-2
935-95-5
Synthesis of 2,3,5,6-TETRACHLOROPHENOL from Chloranil
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2,3,5,6-TETRACHLOROPHENOL, 1X1ML, MEOH 2 000UG/ML 2,3,5,6-TETRACHLOROPHENOL PESTANAL, 10 M 2,3,5,6-TETRACHLOROPHENOL, 50 MG, NEAT 2,3,5,6-tetrachlorophenate 2,3,5,6-TCP 2,3,5,6-TECP 2.3.5.6-Tetrachlorophenol 50mg [935-95-5] Fourchlorophenol NSC 407823 2,3,5,6-Tetrachlorophenol NSC 407823 2.3.5.6-Tetr 2,3,5,6-tetrachloro-pheno Phenol, 2,3,5,6-tetrachloro- phenol,2,3,5,6-tetrachloro 2,3,5,6-Tetrachloropheno1 2,3,5,6-TETRACHLOROPHENOL 2,3,5,6-TetrachlorophenolSolution,1000mg/L,1ml 2,3,5,6-TetrachlorophenolSolution,100mg/L,1ml 2,3,5,6-TetrachlorophenolSolution,2,000mg/L,1ml 2,3,5,6-Tetrachlorophenol Solution, 100μg/mL 2,3,5,6-TetrachlorophenolB 2,3,5,6-Tetrachlorophenol 10.0 μg/ml Cyclohexane 2,3,5,6-Tetrachlorophenol 100 μg/ml Methanol C17375600 2,3,5,6-Tetrachlorophenol L17375600CY 2,3,5,6-TetrachlorophenoL10μg/mL XA17375600CY 2,3,5,6-TetrachlorophenoL100μg/mL 935-95-5 PhenolsInternational Standards Canada Chemical Class ChloroAnalytical Standards Halogenated Single Component Standards for MISA AnalysesVolatiles/ Semivolatiles T-ZAlphabetic Alpha sort Pesticides&Metabolites Q-ZAlphabetic TA - TE PhenolsVolatiles/ Semivolatiles