ChemicalBook >> CAS DataBase List >>Heat Shock Protein Inhibitor II
Heat Shock Protein Inhibitor II
- CAS No.
- 1859-42-3
- Chemical Name:
- Heat Shock Protein Inhibitor II
- Synonyms
- 3-benzo[1,3]dioxol-5-ylmethylene-pyrrolidin-2-one;2-Pyrrolidinone, 3-(1,3-benzodioxol-5-ylmethylene)-;3-(Benzo[d][1,3]dioxol-5-ylmethylene)pyrrolidin-2-one
- CBNumber:
- CB53136752
- Molecular Formula:
- C12H11NO3
- Molecular Weight:
- 217.22
- MDL Number:
- MFCD19104819
- MOL File:
- 1859-42-3.mol
Last updated:2023-05-21 10:59:17
Heat Shock Protein Inhibitor II price More Price(3)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 22358 | Heat Shock Protein Inhibitor II ≥98% | 1859-42-3 | 5mg | $93 | 2024-03-01 | Buy |
| Cayman Chemical | 22358 | Heat Shock Protein Inhibitor II ≥98% | 1859-42-3 | 10mg | $166 | 2024-03-01 | Buy |
| Cayman Chemical | 22358 | Heat Shock Protein Inhibitor II ≥98% | 1859-42-3 | 25mg | $365 | 2024-03-01 | Buy |
Heat Shock Protein Inhibitor II Chemical Properties,Uses,Production
Description
Heat shock protein (Hsp) inhibitor II is the active form of Hsp inhibitor I and a benzylidene lactam compound that prevents the synthesis of inducible Hsps, such as Hsp105, Hsp72, and Hsp40. Hsp inhibitor II decreases Hsp72 synthesis in vivo and reduces thermotolerance of tumors in SCC VII tumor-containing mice. At 100 μM, it inhibits the development of thermotolerance in COLO 320 DM cells. Inhibition of Hsp70 with Hsp inhibitor II in combination with amphotericin B (AmB; ) increases susceptibility of AmB-susceptible (MICs = 0.058 versus 0.27 μg/ml for combined and AmB alone, respectively) and AmB-resistant (MICs = 21.33 versus >32 μg/ml for combined and AmB alone, respectively) strains of A. fumigatus.
Heat Shock Protein Inhibitor II Preparation Products And Raw materials
Raw materials
Preparation Products
Heat Shock Protein Inhibitor II Suppliers
Global( 13)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29825 | 58 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9707 | 58 |
| Tianjin Kailiqi Biotechnology Co., Ltd. | 15076683720 | klq@cw-bio.com | China | 3770 | 55 |
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 | sales@glpbio.cn | China | 6870 | 58 |
| Nanjing Shizhou Biology Technology Co.,Ltd | 025-85560043 13675144456 | sean.lv@synzest.com | China | 11442 | 58 |
| Jinan Jiuli Biotechnology Co. , Ltd. | 15865264761 | 486064515@qq.com | China | 2651 | 58 |
| Bide Pharmatech Ltd. | 400-1647117 15221909166 | product02@bidepharm.com | China | 63720 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 23963 | 58 |
| Henan Alpha Chemical Co., Ltd. | 0371-55013243 15324716602 | 2853979810@qq.com | China | 10010 | 58 |
| Shanghai Yiyan Biotechnology Co. , Ltd. | 021-69985186 13611928337 | 3427709316@qq.com | China | 7980 | 58 |
View Lastest Price from Heat Shock Protein Inhibitor II manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-12-26 | Heat Shock Protein Inhibitor II
1859-42-3
|
US $1.00 / g | 1g | 99% | 200kg | Career Henan Chemical Co |
-
- Heat Shock Protein Inhibitor II
1859-42-3
- US $1.00 / g
- 99%
- Career Henan Chemical Co
3-benzo[1,3]dioxol-5-ylmethylene-pyrrolidin-2-one
3-(Benzo[d][1,3]dioxol-5-ylmethylene)pyrrolidin-2-one
2-Pyrrolidinone, 3-(1,3-benzodioxol-5-ylmethylene)-
1859-42-3