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ACT-462206

CAS No.
1361321-96-1
Chemical Name:
ACT-462206
Synonyms
ACT-462206;ACT 462206,ACT462206;ACT-462206 >=98% (HPLC);(2S)-N-(3,5-DIMETHYLPHENYL)-1-(4-METHOXYPHENYL)SULFONYLPYRROLIDINE-2-CARBOXAMIDE;(2S)-N-(3,5-Dimethylphenyl)-1-[(4-methoxyphenyl)sulfonyl]-2-pyrrolidinecarboxamide;2-Pyrrolidinecarboxamide, N-(3,5-dimethylphenyl)-1-[(4-methoxyphenyl)sulfonyl]-, (2S)-
CBNumber:
CB53167703
Molecular Formula:
C20H24N2O4S
Molecular Weight:
388.48
MDL Number:
MFCD28502270
MOL File:
1361321-96-1.mol
Last updated:2024-07-02 08:55:11

ACT-462206 Properties

Density 1.285±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility Soluble in DMSO
pka 14.27±0.70(Predicted)
form Solid
color White to off-white
FDA UNII 64ONO62P28

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P301+P312+P330

ACT-462206 price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Tocris 5319 ACT462206 ≥99%(HPLC) 1361321-96-1 10 $219 2021-12-16 Buy
Tocris 5319 ACT462206 ≥99%(HPLC) 1361321-96-1 50 $815 2021-12-16 Buy
TRC A305313 ACT462206 1361321-96-1 2.5mg $220 2021-12-16 Buy
Usbiological 254538 ACT 462206 1361321-96-1 10mg $495 2021-12-16 Buy
Product number Packaging Price Buy
5319 10 $219 Buy
5319 50 $815 Buy
A305313 2.5mg $220 Buy
254538 10mg $495 Buy

ACT-462206 Chemical Properties,Uses,Production

Uses

ACT-462206 is a potent and selective dual orexin receptor antagonist (DORA) that inhibits the stimulating effects of the orexin peptides at both the orexin 1 and 2 receptors. It decreases wakefulness and increases non-rapid eye movement (non-REM) and REM sleep while maintaining natural sleep architectures in some animal models while showing anxiolytic-like properties without affecting cognition and motor function in others.

storage

Store at +4°C

15761-39-4
1361321-96-1
Synthesis of ACT-462206 from BOC-L-Proline

ACT-462206 Preparation Products And Raw materials

Raw materials

Preparation Products

ACT-462206 Suppliers

Global( 19)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Aladdin Scientific
+1-+1(833)-552-7181 sales@aladdinsci.com United States 57511 58
HangZhou YuHao Chemical Technology Co., Ltd. 0571-82693216 info@yuhaochemical.com China 2031 58
Shanghai JiYi Biotechnology Co. Ltd. 13621943973 sales@shjiyipharmatech.com China 1166 55
MQ (shanghai) Pharmaceuticals Co., Ltd. 13761635123 1014988033@qq.com China 4966 55
Jinan Yaoyan Pharmaceutical Co., Ltd. jnyaoyan@163.com China 3069 58
Angel Pharmatech, Ltd. 17317130613 3358272972@qq.com China 3249 58
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6870 58
Nanjing Meihao Pharmaceutical Technology Co., Ltd. meitaochem@126.com meitaochem@126.com China 19105 58
BOC Sciences -- info@bocsci.com USA 0 65
ACT-462206 (2S)-N-(3,5-DIMETHYLPHENYL)-1-(4-METHOXYPHENYL)SULFONYLPYRROLIDINE-2-CARBOXAMIDE (2S)-N-(3,5-Dimethylphenyl)-1-[(4-methoxyphenyl)sulfonyl]-2-pyrrolidinecarboxamide ACT-462206 >=98% (HPLC) ACT 462206,ACT462206 2-Pyrrolidinecarboxamide, N-(3,5-dimethylphenyl)-1-[(4-methoxyphenyl)sulfonyl]-, (2S)- 1361321-96-1