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Ac-Gly-BoroPro

Ac-Gly-BoroPro Structure
Ac-Gly-BoroPro structure
CAS No.
886992-99-0
Chemical Name:
Ac-Gly-BoroPro
Synonyms
Ac-Gly-BoroPro;Ac-Gly-BoroPro?, >98%;AcGlyBoroPro,Ac Gly BoroPro;Boronic acid, B-[(2S)-1-[2-(acetylamino)acetyl]-2-pyrrolidinyl]-
CBNumber:
CB53339599
Molecular Formula:
C8H15BN2O4
Molecular Weight:
214.03
MDL Number:
MFCD31544332
MOL File:
886992-99-0.mol
Last updated:2024-07-02 08:55:11
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Ac-Gly-BoroPro Properties

Density 1.26±0.1 g/cm3(Predicted)
storage temp. Store at -20°C,unstable in solution, ready to use.
solubility DMSO : ≥ 50 mg/mL (233.61 mM)
form Solid
pka 9.72±0.20(Predicted)
color White to off-white

Ac-Gly-BoroPro Chemical Properties,Uses,Production

Biological Activity

Ac-Gly-BoroPro is a selective FAP inhibitor with a Ki value of 23 nM.

in vitro

FAP has been implicated in cancer; however, its specific role remains elusive because inhibitors that distinguish FAP from other prolyl peptidases like dipeptidyl peptidase-4 (DPP-4) have not been developed. Ac-Gly-BoroPro selectively inhibits FAP relative to other prolyl peptidases. FAP reacts readily with submicromolar concentrations of Ac-Gly-BoroPro, reaching steady state inhibition levels rapidly (K i =23±3 nM).

target

Ki: 23 nM (FAP)

Ac-Gly-BoroPro Preparation Products And Raw materials

Raw materials

Preparation Products

Ac-Gly-BoroPro Suppliers

Global( 22)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Jilin Chinese Academy of Sciences-yanshen Technology 		+undefined18143011203 info@chemextension.com China 42057 58
Aladdin Scientific 		+1-+1(833)-552-7181 sales@aladdinsci.com United States 52927 58
MedChemexpress LLC 021-58955995 sales@medchemexpress.cn United States 4863 58
BOC Sciences -- info@bocsci.com USA 0 65
Beijing xinyanhui pharmaceutical research and development co., LTD 13969155946 1461866103@qq.com China 16111 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
Shanghai Zeye Biotechnology Co., Ltd. 021-61998551 13122364865 sale1@shzysw.net China 9772 58
Nanchang Tianzhen Biotechnology Co., Ltd 13173652190 pomy@tanzhenbio.com China 1773 58
Ontores Biotech 0571-88760729 18072970094 supports@ontorespeptide.com China 2696 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
Jilin Chinese Academy of Sciences-yanshen Technology 		58
Aladdin Scientific 		58
MedChemexpress LLC 58
BOC Sciences 65
Beijing xinyanhui pharmaceutical research and development co., LTD 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
Shanghai Zeye Biotechnology Co., Ltd. 58
Nanchang Tianzhen Biotechnology Co., Ltd 58
Ontores Biotech 58
Ac-Gly-BoroPro Ac-Gly-BoroPro?, >98% Boronic acid, B-[(2S)-1-[2-(acetylamino)acetyl]-2-pyrrolidinyl]- AcGlyBoroPro,Ac Gly BoroPro 886992-99-0