2,6-Difluorobenzamide
- CAS No.
- 18063-03-1
- Chemical Name:
- 2,6-Difluorobenzamide
- Synonyms
- 2,6-difluorobenzoic acid amide;uorobenzamide;2,6-Difluorbenzamid;2,6-DIFLUOROBENZAMIDE;2,6-difluoro-benzamid;2，6-difluorobenzaminde;2,6-Difluorobenzoamide;2,6-Difluorobenzamide>2,6-Difluorobenzoylamide;2,6-Difluorobenzamide97%
- CBNumber:
- CB5376515
- Molecular Formula:
- C7H5F2NO
- Molecular Weight:
- 157.12
- MDL Number:
- MFCD00007972
- MOL File:
- 18063-03-1.mol
- MSDS File:
- SDS
| Melting point | 145-148 °C (lit.) |
|---|---|
| Boiling point | 51-52C/15Tor |
| Density | 1,199g/cm |
| refractive index | 1,508 |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | ethanol: soluble5%, clear to turbid, colorless to light yellow |
| pka | 14.54±0.50(Predicted) |
| form | Solid |
| color | Off-White |
| BRN | 2047480 |
| InChIKey | AVRQBXVUUXHRMY-UHFFFAOYSA-N |
| LogP | 0.011-0.25 at 25℃ |
| CAS DataBase Reference | 18063-03-1(CAS DataBase Reference) |
| FDA UNII | SJ2RN214MK |
| NIST Chemistry Reference | Benzamide, 2,6-difluoro-(18063-03-1) |
| EPA Substance Registry System | Benzamide, 2,6-difluoro- (18063-03-1) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302 | |||||||||
| Precautionary statements | P264-P270-P301+P312-P501 | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 36/37/38-20 | |||||||||
| Safety Statements | 26-37/39-36/37 | |||||||||
| WGK Germany | 1 | |||||||||
| RTECS | CV4355050 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29242990 | |||||||||
| Toxicity | rat,LC50,inhalation,> 2100mg/m3/4H (2100mg/m3),National Technical Information Service. Vol. OTS0543293, | |||||||||
| NFPA 704 |
|
2,6-Difluorobenzamide price More Price(31)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 282278 | 2,6-Difluorobenzamide 97% | 18063-03-1 | 10g | $22.62 | 2024-03-01 | Buy |
| Sigma-Aldrich | 282278 | 2,6-Difluorobenzamide 97% | 18063-03-1 | 50g | $41.2 | 2024-03-01 | Buy |
| TCI Chemical | D1907 | 2,6-Difluorobenzamide >97.0%(N) | 18063-03-1 | 25g | $30 | 2024-03-01 | Buy |
| Alfa Aesar | A11685 | 2,6-Difluorobenzamide, 98+% | 18063-03-1 | 25g | $53 | 2023-06-20 | Buy |
| Alfa Aesar | A11685 | 2,6-Difluorobenzamide, 98+% | 18063-03-1 | 100g | $139 | 2021-12-16 | Buy |
2,6-Difluorobenzamide Chemical Properties,Uses,Production
Description
2,6-Difluorobenzamide is a major metabolite of pesticide diflubenzuron and has been quantitated by HPLC/diode-array method.
Description
2,6-Difluorobenzamide is a white powdery crystal, insoluble in water. It can be obtained by hydrolysis of 2,6-difluorobenzonitrile. 2,6-Difluorobenzamide is an important intermediate in the synthesis process of benzoylurea insecticides, which is used to synthesize the next intermediate 2,6-difluorobenzoyl isocyanate, and finally obtain flubolurea, pyruron, fluridin, lice mite urea and other pesticide varieties. It can also be directly used to synthesize pyruron and flubolea. 2,6-Difluorobenzamide can inhibit the bacterial cell division protein FtsZ[1].
Chemical Properties
white to yellowish powder
Uses
2,6-Difluorobenzamide (CAS# 18063-03-1) is a useful building block used in the synthesis of (E)-3-methyleneisoindolin-1-ones via oxidative annulation acrylates. It is also used in the synthesis of pesticide intermediates, which can be used to produce various insecticides such as fluazuron, chlorpyrifos, and pyrethroids.
Preparation
2,6-Difluorobenzamide is obtained by hydrolysis of 2,6-difluorobenzonitrile.
References
[1] Straniero V, et al. 2,6-Difluorobenzamide inhibitors of the bacterial cell division protein FtsZ: design, synthesis and Structure Activity Relationship study. ChemMedChem, 2017; 12: 1303-1318.
2,6-Difluorobenzamide Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| AS WATER CO., LTD. | +86-18994963526 +8618994963526 | 1346073549@qq.com | United Kingdom | 176 | 58 |
| Henan Allgreen Chemical Co.,LTD | +86-37155567971 +86-13633837469 | info@allgreenchem.com | China | 5986 | 58 |
| Ningxia Jinhua Chemical Co.,Ltd | 025-52279164 | info@nxjhchem.com | China | 79 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12471 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +8617531190177 | peter@yan-xi.com | China | 6008 | 58 |
| Henan Bao Enluo International TradeCo.，LTD | +86-17331933971 +86-17331933971 | deasea125996@gmail.com | China | 2503 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 18226 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 15956 | 58 |
| Hi-Tech Chemistry Corp | 0519-86626038 | yuhh@hitechem.com | CHINA | 811 | 58 |
View Lastest Price from 2,6-Difluorobenzamide manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-05-20 | 2,6-Difluorobenzamide
18063-03-1
|
US $1.00 / KG | 200KG | 99% | 20ton | Anhui Royal Chemical Co., Ltd. | |
 |
2024-01-22 | 2,6-Difluorobenzamide
18063-03-1
|
US $8.00-0.80 / KG | 1KG | 99% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd | |
 |
2023-11-01 | 2,6-Difluorobenzamide
18063-03-1
|
US $0.00 / kg | 1kg | 98.5% min | 10tons/month | Hangzhou ICH Biofarm Co., Ltd |
-
- 2,6-Difluorobenzamide
18063-03-1
- US $1.00 / KG
- 99%
- Anhui Royal Chemical Co., Ltd.
-
- 2,6-Difluorobenzamide
18063-03-1
- US $8.00-0.80 / KG
- 99%
- Henan Fengda Chemical Co., Ltd
-
- 2,6-Difluorobenzamide
18063-03-1
- US $0.00 / kg
- 98.5% min
- Hangzhou ICH Biofarm Co., Ltd