2-Chloroquinoline
- CAS No.
- 612-62-4
- Chemical Name:
- 2-Chloroquinoline
- Synonyms
- 2CQ;2-chloro-quinolin;2-CHLOROQUINOLINE;Quinoline2-chloro-;2-Chloroquinoline,99%;2-Chloroquinoline >2-Chloroquinoline, 98%+;2-Chloroquinoline ,99.70%;2-Chloroquinoline, 99% 5GR;2-Chloroquinoline, 99% 1GR
- CBNumber:
- CB5403688
- Molecular Formula:
- C9H6ClN
- Molecular Weight:
- 163.6
- MDL Number:
- MFCD00006741
- MOL File:
- 612-62-4.mol
- MSDS File:
- SDS
Melting point | 34-37 °C (lit.) |
---|---|
Boiling point | 266-267 °C (lit.) |
Density | 1.23 g/mL at 25 °C (lit.) |
refractive index | 1.6342 (estimate) |
Flash point | >230 °F |
storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
solubility | methanol: 0.1 g/mL, clear |
pka | 0.41±0.40(Predicted) |
form | Crystalline Powder, Crystals and/or Chunks or Fused Mass |
color | White to yellow |
Water Solubility | Insoluble |
BRN | 112561 |
InChIKey | OFUFXTHGZWIDDB-UHFFFAOYSA-N |
CAS DataBase Reference | 612-62-4(CAS DataBase Reference) |
FDA UNII | UX7RIN8GEW |
NIST Chemistry Reference | Quinoline, 2-chloro-(612-62-4) |
EPA Substance Registry System | Quinoline, 2-chloro- (612-62-4) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
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Signal word | Warning | |||||||||
Hazard statements | H315-H319-H335 | |||||||||
Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
Hazard Codes | Xi | |||||||||
Risk Statements | 36/37/38 | |||||||||
Safety Statements | 26-36-37/39 | |||||||||
WGK Germany | 3 | |||||||||
RTECS | VB2320000 | |||||||||
F | 8 | |||||||||
TSCA | Yes | |||||||||
HS Code | 29334900 | |||||||||
NFPA 704 |
|
2-Chloroquinoline price More Price(31)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | C70401 | 2-Chloroquinoline 99% | 612-62-4 | 5g | $147.6 | 2024-03-01 | Buy |
Sigma-Aldrich | C70401 | 2-Chloroquinoline 99% | 612-62-4 | 1g | $89.5 | 2023-06-20 | Buy |
TCI Chemical | C0282 | 2-Chloroquinoline >98.0%(GC) | 612-62-4 | 5g | $66 | 2024-03-01 | Buy |
TCI Chemical | C0282 | 2-Chloroquinoline >98.0%(GC) | 612-62-4 | 25g | $262 | 2024-03-01 | Buy |
Alfa Aesar | B23443 | 2-Chloroquinoline, 99% | 612-62-4 | 25g | $252 | 2021-12-16 | Buy |
2-Chloroquinoline Chemical Properties,Uses,Production
Chemical Properties
white to yellowish crystals, powder, chunks or
Uses
2-Chloroquinoline is an intermediate used in the synthesis of various compounds that exhibits antifungal properties.
Uses
2-Chloroquinoline is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuff. It reacts with benzotriazole, followed by cyclization with loss of nitrogen, gives the indolo[2,3-b]quinoline ring system for use in novel cytotoxic DNA topoisomerase II inhibitors.
Synthesis Reference(s)
The Journal of Organic Chemistry, 67, p. 7884, 2002 DOI: 10.1021/jo016196i
Synthesis, p. 1013, 1987 DOI: 10.1055/s-1987-28152
Purification Methods
Purify it by crystallisation of its picrate to constant melting point (123-124o) from *benzene, regenerating the base and distilling it under vacuum [Cumper et al. J Chem Soc 1183 1962]. 2-Chloroquinoline can be crystallised from EtOH. Its picrate has m 123-124o (from EtOH). [Beilstein 20 H 359, 20/7 V 312.]
2-Chloroquinoline Preparation Products And Raw materials
Raw materials
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Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20287 | 58 |
Capot Chemical Co.,Ltd. | +86-(0)57185586718 +86-13336195806 | sales@capot.com | China | 29791 | 60 |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 18779 | 58 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21634 | 55 |
Chembon Pharmaceutical Co., Ltd. | +86-28-8425-2981 | CHINA | 722 | 55 | |
Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3009 | 60 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29884 | 58 |
Jinan Finer Chemical Co., Ltd | +86-531-88989536 +86-15508631887 | sales@finerchem.com | China | 2964 | 58 |
Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 17322 | 58 |
BAYNOE CHEM CO.,LTD | +86-21-34783353 +8615000719740 | baynoe@baynoe.com | CHINA | 934 | 58 |
View Lastest Price from 2-Chloroquinoline manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-01-02 | Chloroquinoline
612-62-4
|
US $200.00-1.00 / KG | 1KG | 99%, 99.5% Sublimated | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd | ||
2022-09-28 | 2-Chloroquinoline
612-62-4
|
US $0.00-0.00 / KG | 1KG | 98% | 1ton | Henan Aochuang Chemical Co.,Ltd. | ||
2022-03-04 | 2-Chloroquinoline
612-62-4
|
US $1.10 / g | 1g | 99.00% | 100 Tons | Dideu Industries Group Limited |
- Chloroquinoline
612-62-4
- US $200.00-1.00 / KG
- 99%, 99.5% Sublimated
- Henan Fengda Chemical Co., Ltd
- 2-Chloroquinoline
612-62-4
- US $0.00-0.00 / KG
- 98%
- Henan Aochuang Chemical Co.,Ltd.
- 2-Chloroquinoline
612-62-4
- US $1.10 / g
- 99.00%
- Dideu Industries Group Limited
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