((CYS31,NVA34)-NEUROPEPTIDE Y (27-36))2
- CAS No.
- 172997-92-1
- Chemical Name:
- ((CYS31,NVA34)-NEUROPEPTIDE Y (27-36))2
- Synonyms
- BWX 46;((CYS31,NVA34)-NPY (27-36))2;((Cys??,Nva??)-Neuropeptide Y (27-36))?;((CYS31,NVA34)-NEUROPEPTIDE Y (27-36))2;(H-TYR-ILE-ASN-LEU-CYS-THR-ARG-NVA-ARG-TYR-NH2)2;(H-Tyr-Ile-Asn-Leu-Cys-Thr-Arg-Nva-Arg-Tyr-NH2)2, (Disulfide bond);((Cys31, Nva 34)-Neuropeptide Y (27-36))2 (H-Tyr-Ile-Asn-Leu-Cys-Thr-Arg-Nva-Arg-Tyr-NH2)2 (Disulfide bond);L-Tyrosinamide, L-tyrosyl-L-isoleucyl-L-asparaginyl-L-leucyl-L-cysteinyl-L-threonyl-L-arginyl-L-norvalyl-L-arginyl-, bimol. (5→5')-disulfide
- CBNumber:
- CB5412194
- Molecular Formula:
- C116H186N36O28S2
- Molecular Weight:
- 2597.07
- MDL Number:
- MFCD00798765
- MOL File:
- 172997-92-1.mol
((CYS31,NVA34)-NEUROPEPTIDE Y (27-36))2 price More Price(8)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Usbiological | 254838 | BWX 46 | 172997-92-1 | 1mg | $516 | 2021-12-16 | Buy |
Biosynth Carbosynth | FC109067 | ((Cys31, Nva 34)-Neuropeptide Y (27-36))2 (H-Tyr-Ile-Asn-Leu-Cys-Thr-Arg-Nva-Arg-Tyr-NH2)2 (Disulfide bond) | 172997-92-1 | 1mg | $639 | 2021-12-16 | Buy |
Biosynth Carbosynth | FC109067 | ((Cys31, Nva 34)-Neuropeptide Y (27-36))2 (H-Tyr-Ile-Asn-Leu-Cys-Thr-Arg-Nva-Arg-Tyr-NH2)2 (Disulfide bond) | 172997-92-1 | 2mg | $1111.3 | 2021-12-16 | Buy |
Biosynth Carbosynth | FC109067 | ((Cys31, Nva 34)-Neuropeptide Y (27-36))2 (H-Tyr-Ile-Asn-Leu-Cys-Thr-Arg-Nva-Arg-Tyr-NH2)2 (Disulfide bond) | 172997-92-1 | 100ug | $106 | 2021-12-16 | Buy |
Biosynth Carbosynth | FC109067 | ((Cys31, Nva 34)-Neuropeptide Y (27-36))2 (H-Tyr-Ile-Asn-Leu-Cys-Thr-Arg-Nva-Arg-Tyr-NH2)2 (Disulfide bond) | 172997-92-1 | 250ug | $210 | 2021-12-16 | Buy |
((CYS31,NVA34)-NEUROPEPTIDE Y (27-36))2 Chemical Properties,Uses,Production
Biological Activity
the actions of neuropeptide y (npy) are mediated by at least six g-protein coupled receptors denoted as y1, y2, y3, y4, y5, and y6. investigations using receptor selective ligands and receptor knock-out mice show that npy effects on feeding are mediated by both y1 and y5 receptors. bwx 46 is a y5 receptor selective agonist.
in vitro
bwx 46 selectively bound y5 receptors, and inhibited camp synthesis by y5 cells with potencies comparable to that of npy. in addition, bwx 46 (10 μm) exhibited no significant effect on the camp synthesis by y1, y2, and y4 cells. thus, bwx 46 constitutes the lowest molecular weight y5 selective agonist reported to date [1].
in vivo
intrahypothalamic-injection of 30 and 40 μg of bwx 46 stimulated the food intake by rats in a gradual manner, reaching maximal level 8 h after injection. this response was similar to that exhibited by other y5 selective agonists, but differed from that of npy, which exhibited a rapider orexigenic stimulus within 1 h [1].
IC 50
0.5 nm for y5
References
[1] ambikaipakan balasubramaniam, sulaiman sheriff, weixu zhai, william t. chance. bis(31/31’){[cys31, nva34]npy(27–36)-nh2}: a neuropeptide y (npy) y5 receptor selective agonist with a latent stimulatory effect on food intake in rats. peptides 23 (2002) 1485–1490
((CYS31,NVA34)-NEUROPEPTIDE Y (27-36))2 Preparation Products And Raw materials
Raw materials
Preparation Products
((CYS31,NVA34)-NEUROPEPTIDE Y (27-36))2 Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 16209 | 58 |
Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10260 | 58 |
BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
Shanghai Longyu Biotechnology Co., Ltd. | +8613917842738 | info@longyupharma.com | China | 2534 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29826 | 58 |
Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10522 | 58 |
Alfa Chemistry | +1-5166625404 | Info@alfa-chemistry.com | United States | 21317 | 58 |
Chengdu Youngshe Chemical Co., Ltd. | +8618108235634 | Cecilia@youngshechem.com | China | 2345 | 58 |
Hebei Miaoyin Technology Co.,Ltd | +86-17367732028 +86-17367732028 | kathy@hbyinsheng.com | China | 3582 | 58 |
Nanjing TGpeptide | +86-13347807150 +86-13347807150 | support@tgpeptide.com | China | 3279 | 58 |
View Lastest Price from ((CYS31,NVA34)-NEUROPEPTIDE Y (27-36))2 manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2020-02-14 | ((CYS31,NVA34)-NEUROPEPTIDE Y (27-36))2
172997-92-1
|
US $7.00 / KG | 1KG | 99% | 100KG | Career Henan Chemical Co |
- ((CYS31,NVA34)-NEUROPEPTIDE Y (27-36))2
172997-92-1
- US $7.00 / KG
- 99%
- Career Henan Chemical Co