ChemicalBook >> CAS DataBase List >>Musk ketone
Musk ketone
- CAS No.
- 81-14-1
- Chemical Name:
- Musk ketone
- Synonyms
- KETONE MOSCHUS;(-)-Licarin A;2-Acetyl-5-tert-butyl-4,6-dinitro-1,3-dimethylbenzene;1-(4-(1,1-dimethylethyl)-2,6-dimethyl-3,5-dinitrophenyl)-ethanon;MOSCHUS;MUSK KETONE;Ketone musk;Musk ketone 0;MOSCHUS KETON;MUSK KETONE 98+%
- CBNumber:
- CB5458527
- Molecular Formula:
- C14H18N2O5
- Molecular Weight:
- 294.3
- MDL Number:
- MFCD00024271
- MOL File:
- 81-14-1.mol
- MSDS File:
- SDS
Last updated:2024-11-28 13:16:12
| Melting point | 134-137 °C |
|---|---|
| Boiling point | 436.08°C (rough estimate) |
| Density | 1.2051 (rough estimate) |
| vapor pressure | 0.001Pa at 25℃ |
| refractive index | 1.5110 (estimate) |
| Flash point | 2 °C |
| storage temp. | 2-8°C |
| solubility | DMSO : 250 mg/mL (849.47 mM; Need ultrasonic) |
| form | Solid |
| color | White to off-white |
| Odor | at 10.00 % in benzyl benzoate. fatty musk soapy dry floral powdery |
| Odor Type | musk |
| Water Solubility | Insoluble (<0.1 g/100 mL at 20 ºC) |
| BRN | 2062638 |
| Stability | Stable. Incompatible with strong oxidizing agents, strong acids, strong bases. |
| InChIKey | WXCMHFPAUCOJIG-UHFFFAOYSA-N |
| LogP | 4.24 at 25℃ |
| CAS DataBase Reference | 81-14-1(CAS DataBase Reference) |
| Substances Added to Food (formerly EAFUS) | MUSK, KETONE |
| EWG's Food Scores | 3-4 |
| FDA UNII | 483V3E1L6J |
| NIST Chemistry Reference | 2,6-Dimethyl-3,5-dinitro-4-t-butylacetophenone(81-14-1) |
| EPA Substance Registry System | Musk ketone (81-14-1) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |     GHS02,GHS07,GHS08,GHS09 |
|---|---|
| Signal word | Danger |
| Hazard statements | H225-H302-H312-H319-H332-H351-H410 |
| Precautionary statements | P210-P280-P305+P351+P338-P273-P281-P501 |
| Hazard Codes | F,Xn,N |
| Risk Statements | 11-20/21/22-36-50/53-40 |
| Safety Statements | 16-36/37-61-60-46 |
| RIDADR | UN1648 3/PG 2 |
| WGK Germany | 2 |
| RTECS | KM5775841 |
| HS Code | 2914790060 |
| Toxicity | Both the acute oral LD50 in rats and the acute dermal LD50 in rabbits exceeded 10 g/kg (Fogleman, 1970). |
Musk ketone price More Price(13)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 46377 | Musk ketone solution 100 μg/mL in acetonitrile, analytical standard | 81-14-1 | 2ml | $75 | 2022-05-15 | Buy |
| Sigma-Aldrich | S342963 | 4'-TERT-BUTYL-2',6'-DIMETHYL-3',5'-DINITROACETOPHENONE AldrichCPR | 81-14-1 | 1g | $179 | 2024-03-01 | Buy |
| Sigma-Aldrich | W522902 | Musk ketone ≥98% | 81-14-1 | sample | $52 | 2022-05-15 | Buy |
| AK Scientific | 6206AF | Musk ketone | 81-14-1 | 100g | $68 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FB55046 | 4'-tert-Butyl-2',6'-dimethyl-3',5'-dinitroacetophenone | 81-14-1 | 250g | $80 | 2021-12-16 | Buy |
Musk ketone Chemical Properties,Uses,Production
Chemical Properties
White to light yellow crystal powde
Chemical Properties
It forms yellowish crystals with a sweet, very
persistent, slightly animal musk odor.Musk ketone is prepared by Friedel–Crafts
acetylation of 1,3-dimethyl-5-tert-butylbenzene and nitration of the resulting 2,6-
dimethyl-4-tert-butylacetophenone with nitric acid.
Musk ketone is widely used as a fixative in blossom and fantasy compositions.
Occurrence
Has apparently not been reported to occur in nature.
Uses
Musk ketone is used as fragrance and fixative in after-shave lotions, perfumes, ete.
Preparation
Nitration of the corresponding benzene derivative (Bedoukian, 1967).
Definition
ChEBI: 4'-tert-Butyl-2',6'-dimethyl-3',5'-dinitroacetophenone is an aromatic ketone.
General Description
Light yellow crystalline solid. Insoluble in water.
Air & Water Reactions
Insoluble in water.
Reactivity Profile
A nitrated ketone. Ketones are reactive with many acids and bases liberating heat and flammable gases (e.g., H2). The amount of heat may be sufficient to start a fire in the unreacted portion of the ketone. Ketones react with reducing agents such as hydrides, alkali metals, and nitrides to produce flammable gas (H2) and heat. Ketones are incompatible with isocyanates, aldehydes, cyanides, peroxides, and anhydrides. They react violently with aldehydes, HNO3, HNO3 + H2O2, and HClO4.
Fire Hazard
Flash point data is not available for Musk ketone, however, Musk ketone is probably combustible.
Flammability and Explosibility
Not classified
Purification Methods
Purify the ketone by recrystallisation from MeOH. It has a strong odour of musk and is used in perfumery. [Fuson et al. J Org Chem 12 587 1947, Beilstein 7 IV 808.]
Musk ketone Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
Global( 309)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Changzhou AniKare Pharmatech Co., Ltd. | +86-0519-8359-8696 +8618018249389 | sales@anikare.com | China | 9302 | 58 |
| Hebei Weibang Biotechnology Co., Ltd | +8615531157085 | abby@weibangbio.com | China | 8810 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12839 | 58 |
| Hebei Kingfiner Technology Development Co.Ltd | +86-15532196582 +86-15373005021 | lisa@kingfinertech.com | China | 3010 | 58 |
| Shandong Deshang Chemical Co., Ltd. | +86-0531-8875-2665 +8613153039501 | info@deshangchem.com | China | 662 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21634 | 55 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3619 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29881 | 58 |
| Nanjing Dolon Biotechnology Co.,Ltd. | 18905173768 | sales@dolonchem.com | CHINA | 2972 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
View Lastest Price from Musk ketone manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-28 | Musk ketone
81-14-1
|
US $45.00 / kg | 1kg | 99% | 20 tons | Hebei Zhuanglai Chemical Trading Co Ltd | |
 |
2024-11-22 | Musk ketone
81-14-1
|
US $1.00 / kg | 1kg | 99% | 10 mt | Hebei Weibang Biotechnology Co., Ltd | |
 |
2024-11-19 | Musk ketone
81-14-1
|
US $70.00-31.00 / mg | 99.85% | 10g | TargetMol Chemicals Inc. |
-
- Musk ketone
81-14-1
- US $45.00 / kg
- 99%
- Hebei Zhuanglai Chemical Trading Co Ltd
-
- Musk ketone
81-14-1
- US $1.00 / kg
- 99%
- Hebei Weibang Biotechnology Co., Ltd
-
- Musk ketone
81-14-1
- US $70.00-31.00 / mg
- 99.85%
- TargetMol Chemicals Inc.
81-14-1(Musk ketone)Related Search:
MUSK KETONE
MOSCHUS
2,6-DINITRO-3,5-DIMETHYL-4-ACETYL-TERT-BUTYLBENZENE
1-[4-(TERT-BUTYL)-2,6-DIMETHYL-3,5-DINITROPHENYL]ETHAN-1-ONE
1-(4-TERT-BUTYL-2,6-DIMETHYL-3,5-DINITRO-PHENYL)-ETHANONE
4-TERT-BUTYL-3,5-DINITRO-2,6-DIMETHYL ACETOPHENONE
4-TERT-BUTYL-2,6-DIMETHYL-3,5-DINITROACETOPHENONE
3',5'-Dinitro-4'-tert-butyl-2',6'-dimethylacetophenone
3, 5-Dinitro-4-t-butyl-2, 6-dimethylacetophenone
Ketone Moschus,4-tert-Butyl-2,6-dimethyl-3,5-dinitroacetophenone, Musk ketone
Musk ketone,4-tert-Butyl-2,6-dimethyl-3,5-dinitroacetophenone, Ketone Moschus
Musk ketone 0
Ketone Moschus >=97.0% (N)
1-[4-(1,1-dimethylethyl)-2,6-dimethyl-3,5-dinitrophenyl]-ethanon
1-Acetyl-4-tert-butyl-2,6-dimethyl-3,5-dinitrobenzene
2-acetyl-5-tert-butyl-4,6-dinitroxylene
3,5-Dinitro-2,6-dimethyl-4-tert-butyl acetophenone
MUSK KETONE 98+%
4-Aceto-3,5-dimethyl-2,6-dinitro-tert-butylbenzene
2,6-DIMETHYL-3,5-DINITRO-4-TERT-BUTYLACETOPHENONE(MUSKKETONE)
3’,5’-dinitro-2’,6’-dimethyl-4’-tert-butylacetophenone
MOSCHUS KETON
1-[4-(1,1-dimethylethyl)-2,6-dimethyl-3,5-dinitrophenyl]ethanone
2',6'-Dimethyl-3',5'-dinitro-4'-tert-butylacetophenone
3-METHYLCYCLOPENTADECANONE (D,L-MUSCONE)
4-tert-Butyl-2,6-dimethyl-3,5-dinitroacetophenone, Ketone Moschus
4’-tert-butyl-2’,6’-dimethyl-3’,5’-dinitro-acetophenon
4’-tert-Butyl-2’,6-dimethyl-3’,5’dmnitroacetophenone
4-t-Butyl-2,6-dimethyl-3,5-dinitroacetophenone
4-tert-Butyl-2,6-dimethyl-3,5-dinitroactophenone
Acetophenone, 4'-tert-butyl-2',6'-dimethyl-3',5'-dinitro-
Acetyl-dinitro-butyl-xylene
Dinitro-tert-butylxylyl methyl ketone
Ethanone, 1-[4-(1,1-dimethylethyl)-2,6-dimethyl-3,5-dinitrophenyl]-
Ethanone,1-[4-(1,1-dimethylethyl)-2,6-dimethyl-3,5-dinitrophenyl]-
Ketone musk
Synthetic Musk ketone
Musk ketone Solution in Methanol, 100μg/mL
Musk ketone USP/EP/BP
Best Price CAS 81-14-1 Musk Ketone Powder
Methylcyclopentadecanone
KETONE MOSCHUS
2-Acetyl-5-tert-butyl-4,6-dinitro-1,3-dimethylbenzene
1-(4-(1,1-dimethylethyl)-2,6-dimethyl-3,5-dinitrophenyl)-ethanon
(-)-Licarin A
Musk ketone in acetonitrile
Musk ketone in isooctane
Musk ketone 10.0 μg/ml Cyclohexane
81-14-1
81-41-1
CH3COC6HC4H9CH3NO22
CH3C15H27O
CH33CC6NO22CH32COCH3
C13 to C14
Carbonyl Compounds
Building Blocks
Ketones
Organic Building Blocks