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Cyclo(L-Phe-L-Val)

CAS No.
35590-86-4
Chemical Name:
Cyclo(L-Phe-L-Val)
Synonyms
Cyclo(L-Phe-L-Val);Cyclo(-L-Val-L-Phe);(3S,6S)-3-benzyl-6-isopropylpiperazine-2,5-dione;3S-(1-methylethyl)-6S-(phenylmethyl)-2,5-piperazinedione;(3S,6S)-3-(1-methylethyl)-6-(phenylmethyl)piperazine-2,5-dione;2,5-Piperazinedione, 3-(1-methylethyl)-6-(phenylmethyl)-, (3S,6S)-
CBNumber:
CB54666988
Molecular Formula:
C14H18N2O2
Molecular Weight:
246.3
MDL Number:
MFCD33021199
MOL File:
35590-86-4.mol
MSDS File:
SDS
Last updated:2024-07-02 08:55:11

Cyclo(L-Phe-L-Val) Properties

Melting point 176-178 °C
Boiling point 515.6±43.0 °C(Predicted)
Density 1.109±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble
form A solid
pka 13.12±0.60(Predicted)
color White to off-white

Cyclo(L-Phe-L-Val) price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 24943 Cyclo(L-Phe-L-Val) ≥95% 35590-86-4 5mg $242 2024-03-01 Buy
Cayman Chemical 24943 Cyclo(L-Phe-L-Val) ≥95% 35590-86-4 25mg $965 2024-03-01 Buy
AK Scientific 9259CU (3S,6S)-3-Benzyl-6-isopropyl-piperazine-2,5-dione 35590-86-4 25mg $1174 2021-12-16 Buy
Product number Packaging Price Buy
24943 5mg $242 Buy
24943 25mg $965 Buy
9259CU 25mg $1174 Buy

Cyclo(L-Phe-L-Val) Chemical Properties,Uses,Production

Description

Cyclo(L-Phe-L-Val) is a metabolite of the sponge bacterium Pseudoalteromonas sp. NJ6-3-1 that can autoinduce production of antibacterial substances active against S. aureus when co-cultured at a low cell density. It induces neurite outgrowth and branching of chick cortical neurons in vitro when used at concentrations of 16 and 32 μM. It increases phosphorylation of the PI3K substrate Akt, and neurite outgrowth induced by cyclo(L-Phe-L-Val) can be blocked by the PI3K inhibitor LY294002 . Cyclo(L-Phe-L-Val) enhances axon sprouting of calcitonin gene-related protein positive (CGRP+) primary afferents in the spinal cord following crush injury and of serotonin neurons in uninjured spinal cord. Cyclo(L-Phe-L-Val) is also a bitter taste component of cocoa and roasted coffee.

Cyclo(L-Phe-L-Val) Preparation Products And Raw materials

Raw materials

Preparation Products

Cyclo(L-Phe-L-Val) Suppliers

Global( 12)Suppliers
Supplier Tel Email Country ProdList Advantage
BOC Sciences
16314854226; +16314854226 inquiry@bocsci.com United States 19743 58
Aladdin Scientific
+1-+1(833)-552-7181 sales@aladdinsci.com United States 52927 58
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9806 58
Hangzhou Peptidego Biotech Co.,Ltd. 0571-87213919 eric@peptidego.com China 6757 58
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6870 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
Meng Cheng Technology (Shanghai) Co., LTD 400-820-6829 sales@mitachieve.com China 8864 58
Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd 0431-80514535 19917294565 caoy@chemextension.com China 4758 58
Hangzhou Sinoda Pharmaceutical Technology Co. LTD 0571-87213919 17306812703 3007955328@qq.com China 6445 58
Aikon International Limited 18626450290 yftan@aikonchem.com China 10718 58
Cyclo(L-Phe-L-Val) (3S,6S)-3-(1-methylethyl)-6-(phenylmethyl)piperazine-2,5-dione Cyclo(-L-Val-L-Phe) 2,5-Piperazinedione, 3-(1-methylethyl)-6-(phenylmethyl)-, (3S,6S)- 3S-(1-methylethyl)-6S-(phenylmethyl)-2,5-piperazinedione (3S,6S)-3-benzyl-6-isopropylpiperazine-2,5-dione 35590-86-4