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MGV354
- CAS No.
- 1852495-86-3
- Chemical Name:
- MGV354
- Synonyms
- MGV354;(Rac)-MGV354;MGV354|MGV 354;pressure,drop,intraocular,Guanylate Cyclase,(Rac)MGV354,Inhibitor,activator,topical,(Rac) MGV354,inhibit,sGC,(Rac)-MGV354,(Rac)-MGV-354,ocular
- CBNumber:
- CB54668179
- Molecular Formula:
- C35H37N5O3
- Molecular Weight:
- 575.71
- MDL Number:
- MFCD32664441
- MOL File:
- 1852495-86-3.mol
Last updated:2024-07-02 08:55:11
MGV354 Chemical Properties,Uses,Production
Biological Activity
(Rac)-MGV354 is the racemate of MGV354. MGV354 is a soluble guanylate cyclase (sGC) activator with EC50s of <0.5 nM, and 5 nM in CHO and GTM-3 E cells, respectively[1].
References
[1]. Ehara T, et al. The Discovery of ( S)-1-(6-(3-((4-(1-(Cyclopropanecarbonyl)piperidin-4-yl)-2-methylphenyl)amino)-2,3-dihydro-1 H-inden-4-yl)pyridin-2-yl)-5-methyl-1 H-pyrazole-4-carboxylic Acid, a Soluble Guanylate Cyclase Activator Specifically Designed for Topical Ocular Delivery as a Therapy for Glaucoma. J Med Chem. 2018 Mar 22;61(6):2552-2570.
MGV354 Preparation Products And Raw materials
Raw materials
Preparation Products
MGV354 Suppliers
Global( 30)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
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ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32836 | 60 |
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MGV354
(Rac)-MGV354
pressure,drop,intraocular,Guanylate Cyclase,(Rac)MGV354,Inhibitor,activator,topical,(Rac) MGV354,inhibit,sGC,(Rac)-MGV354,(Rac)-MGV-354,ocular
MGV354|MGV 354
1852495-86-3