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2,6-Difluoroaniline

CAS No.
5509-65-9
Chemical Name:
2,6-Difluoroaniline
Synonyms
2,6-Difuluoroaniline;2,6-DIFLUOROBENZENAMINE;NSC 127234;JACS-5509-65-9;6-Difluoroaniline;2,6-DIFLUOROANILINE;2,6- twofluoro aniline;2,6-Difluoroaniline>Abemaciclib Impurity 9;Vandetanib Impurity 13
CBNumber:
CB5478710
Molecular Formula:
C6H5F2N
Molecular Weight:
129.11
MDL Number:
MFCD00007655
MOL File:
5509-65-9.mol
MSDS File:
SDS
Last updated:2024-11-08 14:53:31

2,6-Difluoroaniline Properties

Boiling point 51-52 °C/15 mmHg (lit.)
Density 1.199 g/mL at 25 °C (lit.)
refractive index n20/D 1.508(lit.)
Flash point 110 °F
storage temp. Keep in dark place,Sealed in dry,2-8°C
solubility Chloroform, Ethyl Acetate (Slightly)
form Liquid
pka 1.81±0.10(Predicted)
Specific Gravity 1.28
color Clear yellow to brown
Water Solubility Slightly soluble in water.
BRN 2802697
Stability Hygroscopic
InChIKey ODUZJBKKYBQIBX-UHFFFAOYSA-N
CAS DataBase Reference 5509-65-9(CAS DataBase Reference)
FDA UNII 943G3H8895
NIST Chemistry Reference 2,6-Difluoroaniline(5509-65-9)
EPA Substance Registry System 2,6-Difluoroaniline (5509-65-9)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS02,GHS07
Signal word  Warning
Hazard statements  H226-H302+H312+H332-H317
Precautionary statements  P210-P233-P280-P301+P312-P303+P361+P353-P304+P340+P312
Hazard Codes  Xn,Xi,F
Risk Statements  10-20/21/22-36/37/38
Safety Statements  36-36/37/39-26-23-16-16/23/26/36/37/39-24/25
RIDADR  UN 1993 3/PG 3
WGK Germany  3
8-10-23
Hazard Note  Irritant
HazardClass  3
PackingGroup  III
HS Code  29214210
NFPA 704
2
2 0

2,6-Difluoroaniline price More Price(34)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 196614 2,6-Difluoroaniline ≥97% 5509-65-9 5g $54.4 2024-03-01 Buy
Sigma-Aldrich 196614 2,6-Difluoroaniline ≥97% 5509-65-9 25g $72.1 2024-03-01 Buy
TCI Chemical D1635 2,6-Difluoroaniline >98.0%(GC) 5509-65-9 5g $26 2024-03-01 Buy
TCI Chemical D1635 2,6-Difluoroaniline >98.0%(GC) 5509-65-9 25g $77 2024-03-01 Buy
Alfa Aesar A13020 2,6-Difluoroaniline, 98% 5509-65-9 5g $37.65 2024-03-01 Buy
Product number Packaging Price Buy
196614 5g $54.4 Buy
196614 25g $72.1 Buy
D1635 5g $26 Buy
D1635 25g $77 Buy
A13020 5g $37.65 Buy

2,6-Difluoroaniline Chemical Properties,Uses,Production

Chemical Properties

clear yellow to brown liquid

Uses

2,6-Difluoroaniline was used in the synthesis of:

  • N-2,6-difluorophenyl-5-methoxy-1,2,4-triazolo[1,5-a]pyrimidine-2-sulfonamide, herbicidal compound
  • series of 2,6,9-trisubstituted purine inhibitors of p38α kinase
  • substituted phenylthiomorpholine dioxide, an active pharmaceutical intermediate

Uses

2,6-Difluoroaniline and several related primary amines are oxidized in chloroform by peroxybenzoic acid to the corresponding nitroso compounds. For example, treatment of 2,6-difluoroaniline with sodium azide can obtain 4-fluoro-2,1,3-benzoxadiazole, and the product is nitrified to obtain 7-nitro derivatives[1]. 2,6-Difluoroaniline is an important raw material and intermediate in organic synthesis, medicine, pesticides, dyes and other fields.

Uses

2,6-Difluoroaniline is an important chemical in the sythesis technology for high-efficiency insecticide.

References

[1] Nunno L, et al. Oxidation of substituted anilines to nitroso-compounds. J. Chem. Soc. C, 1970; 9: 1433-1434.

Global( 567)Suppliers
Supplier Tel Email Country ProdList Advantage
Ningxia Jinhua Chemical Co.,Ltd
025-52279164 info@nxjhchem.com China 79 58
Hebei Weibang Biotechnology Co., Ltd
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Hebei Mojin Biotechnology Co., Ltd
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Fluoropharm Co., Ltd.
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ATK CHEMICAL COMPANY LIMITED
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View Lastest Price from 2,6-Difluoroaniline manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2,6-Difluoroaniline pictures 2024-11-22 2,6-Difluoroaniline
5509-65-9
US $1.00 / KG 100KG 99 1000 Ningxia Jinhua Chemical Co.,Ltd
	2,6-Difluoroaniline pictures 2024-11-08 2,6-Difluoroaniline
5509-65-9
US $0.00 / KG 1KG 99% 10 mt Hebei Weibang Biotechnology Co., Ltd
2,6-Difluoroaniline pictures 2024-10-11 2,6-Difluoroaniline
5509-65-9
US $5.00-2.00 / KG 1KG 99% 10000kg Hebei Chuanghai Biotechnology Co,.LTD
Benzenamine, 2,6-difluoro- 2,6-DIFLUOROANILINE 2,6-DIFLUOROANILINE, 97+% 2,6-Difluoroaniline,98% 2,6-Difluoroaniline,min.97% 2,6-Difluoroaniline 98% 2,6-Difluoroaniline, min. 97% 2,6-Difuluorobenzenamine 2,6-DifluorobenzeneaMine 2,6-DifluorophenylaMine NSC 127234 6-Difluoroaniline 2-Amino-1,3-difluorobenzene 2,6-Difluoroaniline, 97% 5ML 2,6- twofluoro aniline 2,6-Difluoroaniline 98%, 6-Difluoroaniline 98% 2,6-Difluoroaniline 98% Min. JACS-5509-65-9 2,6-Difluoroaniline> 2,6-Difluoroaniline ISO 9001:2015 REACH 2,6-DIFLUOROBENZENAMINE 2,6-Difuluoroaniline Abemaciclib Impurity 9 Vandetanib Impurity 13 5509-65-9 F2C6H3NH2 C6F2H5N1 C2 to C6 Amines Building Blocks Organic Building Blocks Nitrogen Compounds Anilines, Aromatic Amines and Nitro Compounds Fluorobenzene Miscellaneous Fluorobenzene Series Amines C2 to C6 Nitrogen Compounds bc0001