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PORPHOBILINOGEN

CAS No.
487-90-1
Chemical Name:
PORPHOBILINOGEN
Synonyms
PBG;PORPHOBILINOGEN;porphobilinogen (synth.);5-(Aminomethyl)-4-(carboxymethyl)pyrrole-3-propionic acid;5-(aminomethyl)-4-(carboxymethyl)-1h-pyrrole-3-propanoicaci;5-(aminomethyl)-4-(carboxymethyl)-1H-pyrrole-3-propionic acid;5-[AMINOMETHYL]-4-[CARBOXYMETHYL]-1H-PYRROLE-3-PROPANOIC ACID;1H-Pyrrole-3-propanoic acid, 5-(aminomethyl)-4-(carboxymethyl)-;3-[5-(aminomethyl)-4-(carboxymethyl)-1H-pyrrol-3-yl]propionic acid;3-[5-(aminomethyl)-4-(carboxymethyl)-1H-pyrrol-3-yl]propanoic acid
CBNumber:
CB5481219
Molecular Formula:
C10H14N2O4
Molecular Weight:
226.23
MDL Number:
MFCD00005224
MOL File:
487-90-1.mol
MSDS File:
SDS
Last updated:2024-12-18 14:08:52

PORPHOBILINOGEN Properties

Melting point 174-177℃
Boiling point 479℃
Density 1.421
Flash point 243℃
storage temp. -20°C
solubility Aqueous Base (Slightly), Acetonitrile (Slightly), DMSO (Slightly)
pka 4.22±0.10(Predicted)
form powder
color light yellow to pink
Merck 13,7681
BRN 220051
FDA UNII 74KHC72QXK
EPA Substance Registry System Porphobilinogen (487-90-1)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
8-10

PORPHOBILINOGEN price More Price(9)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich P1134 Porphobilinogen powder 487-90-1 1mg $110 2024-03-01 Buy
Sigma-Aldrich P1134 Porphobilinogen powder 487-90-1 5mg $365 2024-03-01 Buy
Sigma-Aldrich P1134 Porphobilinogen powder 487-90-1 10mg $688 2024-03-01 Buy
Sigma-Aldrich P1134 Porphobilinogen powder 487-90-1 50mg $2130 2024-03-01 Buy
Usbiological 287240 Porphobilinogen 487-90-1 25mg $955 2021-12-16 Buy
Product number Packaging Price Buy
P1134 1mg $110 Buy
P1134 5mg $365 Buy
P1134 10mg $688 Buy
P1134 50mg $2130 Buy
287240 25mg $955 Buy

PORPHOBILINOGEN Chemical Properties,Uses,Production

Uses

An intermediate in the biosynthesis of Heme, found in the urine of patients with acute porphyria.

Definition

ChEBI: Porphobilinogen is a dicarboxylic acid that is pyrole bearing aminomethyl, carboxymethyl and 2-carboxyethyl substituents at positions 2, 3 and 4 respectively. It has a role as a metabolite, an Escherichia coli metabolite and a mouse metabolite. It is a member of pyrroles, a dicarboxylic acid and an aralkylamino compound. It is a conjugate acid of a porphobilinogen(1-).

Biochem/physiol Actions

Intermediate in the biosynthesis of heme.

Purification Methods

Porphobilinogen recrystallises as the monohydrate (pink crystals) from dilute NH4 OAc solutions of pH 4, and is dried in vacuo. The hydrochloride monohydrate has m 165-170o(dec) (from dilute HCl). [Jackson & MacDonald Can J Chem 35 715 1957, Westall Nature 170 614 1952, Bogarad J Am Chem Soc 75 3610 1953, Beilstein 22/14 V 210.]

PORPHOBILINOGEN Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 46)Suppliers
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Shanghai Zheyan Biotech Co., Ltd.
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Chengdu Aslee Biopharmaceuticals, Inc.
28-85305008 CHINA 964 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32161 58
GLR Innovations
+91 9891111994 info@glrgroup.in India 4535 58
Jilin Chinese Academy of Sciences-yanshen Technology
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J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 jkinfo@jkchemical.com China 96815 76
Chemsky (shanghai) International Co.,Ltd 021-50135380 shchemsky@sina.com China 15402 60
Tianjin heowns Biochemical Technology Co., Ltd. 400 638 7771 sales@heowns.com China 14435 57
Shanghai TaoSu Biochemical Technology Co., Ltd. 021-33632979 info@tsbiochem.com China 8065 58
Chengdu Aslee Biopharmaceuticals, Inc 028-85305008 02885305008 2306208234@qq.com China 1006 50
5-(aminomethyl)-4-(carboxymethyl)-1h-pyrrole-3-propanoicaci PORPHOBILINOGEN porphobilinogen (synth.) 5-(aminomethyl)-4-(carboxymethyl)-1H-pyrrole-3-propionic acid 3-[5-(aminomethyl)-4-(carboxymethyl)-1H-pyrrol-3-yl]propanoic acid 5-[AMINOMETHYL]-4-[CARBOXYMETHYL]-1H-PYRROLE-3-PROPANOIC ACID 5-(Aminomethyl)-4-(carboxymethyl)pyrrole-3-propionic acid 3-[5-(aminomethyl)-4-(carboxymethyl)-1H-pyrrol-3-yl]propionic acid 1H-Pyrrole-3-propanoic acid, 5-(aminomethyl)-4-(carboxymethyl)- PBG 487-90-1 C10H14N2O4xH2O Biochemicals and Reagents BioChemical Porphobilinogen deaminase Porphyrin Substrates by Enzyme Metabolomics Metabolic Pathways Metabolites and Cofactors on the Metabolic Pathways Chart Enzymes, Inhibitors, and Substrates Enzyme Substrates organic building block Porphyrins Precursers Amines Heterocycles Intermediates & Fine Chemicals Pharmaceuticals Elisa Kit-plant ELISA Kit