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5-Aminouridine

5-Aminouridine Structure
5-Aminouridine structure
CAS No.
2149-76-0
Chemical Name:
5-Aminouridine
Synonyms
5-aminouridine;5-Amino-uridin;Uridine, 5-amino-;5-Aminouridine Hcl;5-AminouridineHClsalt;Uridine, 5-amino-(6CI,7CI,8CI,9CI);5-amino-1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione;5-azanyl-1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione;5-amino-1-(3,4-dihydroxy-5-methylol-tetrahydrofuran-2-yl)pyrimidine-2,4-quinone;5-Amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
CBNumber:
CB5496873
Molecular Formula:
C9H13N3O6
Molecular Weight:
259.22
MDL Number:
MFCD00038055
MOL File:
2149-76-0.mol
MSDS File:
SDS
Last updated:2024-11-19 23:02:33
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5-Aminouridine Properties

Melting point 214-216 °C
Density 1.712±0.06 g/cm3(Predicted)
storage temp. −20°C
pka 9.31±0.10(Predicted)
InChI InChI=1S/C9H13N3O6/c10-3-1-12(9(17)11-7(3)16)8-6(15)5(14)4(2-13)18-8/h1,4-6,8,13-15H,2,10H2,(H,11,16,17)/t4-,5-,6-,8-/m1/s1
InChIKey YBTWWWIJBCCYNR-UAKXSSHOSA-N
SMILES OC[C@H]1O[C@@H](N2C=C(N)C(=O)NC2=O)[C@H](O)[C@@H]1O

SAFETY

Risk and Safety Statements

WGK Germany  3

5-Aminouridine price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Crysdot CD70001702 5-Amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione 95+% 2149-76-0 250mg $300 2021-12-16 Buy
Chemenu CM322243 5-Amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione 95% 2149-76-0 1g $701 2021-12-16 Buy
Crysdot CD70001702 5-Amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione 95+% 2149-76-0 1g $750 2021-12-16 Buy
Product number Packaging Price Buy
CD70001702 250mg $300 Buy
CM322243 1g $701 Buy
CD70001702 1g $750 Buy

5-Aminouridine Chemical Properties,Uses,Production

Description

5-Aminouridine can modify nucleobases and can be incorporated into the target DNA. 5-Aminouridine exhibits a wide range of biological activity and it inhibits the growth of tumors, fungi and viruses.

in vitro

This modified nucleobase, 5-Aminouridine, must exhibit a low enough potential to be oxidized by Os(bpy)33+. These modified nucleobases can be inserted into the target DNA by direct synthesis using modified phosphoramidites

in vivo

5-Aminouridine inhibits the incorporation of carbamyl aspartate into pyrimidines of both RNA and DNA in rat lived and [32P]phosphate into phospholipids and RNA nucleotides of rat liver slices and hepatoma. 5-Aminouridine was found to be incorporated into the RNA of Ehrlich ascites cells, and 5-aminouridine monophosphate was shown to be a strong inhibitor of orotidine 5'-phosphate decarboxylase[1].

References

[1] David A. Smith, Donald W. Visser, P. Roy-Burman. “Studies on 5-aminouridine.” Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis 119 2 (1966): Pages 221-228.

5-Aminouridine Preparation Products And Raw materials

Raw materials

Preparation Products

5-Aminouridine Suppliers

Global( 33)Suppliers
Supplier Tel Email Country ProdList Advantage
PANNACEAN(HENAN)MEDICINE SCIENCE TECHNOLOGIES LTD
0371-55159968 18137130222 haifeng.zhang@pannacean.com China 645 58
Shenzhen Nexconn Pharmatechs Ltd 		+86-755-89396905 +86-15013857715 admin@nexconn.com China 10311 58
SHANGHAI T&W PHARMACEUTICAL CO., LTD. 		+86-021-61551413 +8618813727289 contact@trustwe.com China 5738 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32161 58
BOC Sciences 		16314854226; +16314854226 inquiry@bocsci.com United States 19741 58
NewCan Biotech Limited 		+86-0571-86912261 +8613735419629 sales@newcanbio.com China 9981 58
TargetMol Chemicals Inc. 		support@targetmol.com United States 38631 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131957 58
T&W GROUP 021-61551611 13296011611 contact@trustwe.com China 9895 58
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9806 58
Supplier Advantage
PANNACEAN(HENAN)MEDICINE SCIENCE TECHNOLOGIES LTD
58
Shenzhen Nexconn Pharmatechs Ltd 		58
SHANGHAI T&W PHARMACEUTICAL CO., LTD. 		58
TargetMol Chemicals Inc. 		58
BOC Sciences 		58
NewCan Biotech Limited 		58
TargetMol Chemicals Inc. 		58
Amadis Chemical Company Limited 		58
T&W GROUP 58
Shanghai EFE Biological Technology Co., Ltd. 58

View Lastest Price from 5-Aminouridine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
5-Aminouridine pictures 2024-11-19 5-Aminouridine
2149-76-0
 US $50.00-114.00 / mg 100% 10g TargetMol Chemicals Inc.
5-Aminouridine pictures 2024-11-19 5-Aminouridine
2149-76-0
 US $50.00-114.00 / mg 100% 10g TargetMol Chemicals Inc.
  • 5-Aminouridine pictures
  • 5-Aminouridine
    2149-76-0
  • US $50.00-114.00 / mg
  • 100%
  • TargetMol Chemicals Inc.
  • 5-Aminouridine pictures
  • 5-Aminouridine
    2149-76-0
  • US $50.00-114.00 / mg
  • 100%
  • TargetMol Chemicals Inc.

5-Aminouridine Spectrum

5-AMINOURIDINE, HYDROCHLORIDE SALT(2149-76-0)1HNMR
5-aminouridine 5-AminouridineHClsalt 5-amino-1-(3,4-dihydroxy-5-methylol-tetrahydrofuran-2-yl)pyrimidine-2,4-quinone 5-amino-1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione 5-azanyl-1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione 5-Aminouridine Hcl Uridine, 5-amino-(6CI,7CI,8CI,9CI) 5-Amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione Uridine, 5-amino- 5-Amino-uridin 2149-76-0 C9H14ClN3O6 C9H13N3O6HCl