ChemicalBook >> CAS DataBase List >>5-(2-BENZOTHIAZOLYL)-3-ETHYL-2-(-(METHY
5-(2-BENZOTHIAZOLYL)-3-ETHYL-2-(-(METHY
- CAS No.
- 681281-88-9
- Chemical Name:
- 5-(2-BENZOTHIAZOLYL)-3-ETHYL-2-(-(METHY
- Synonyms
- 5-(2-BENZOTHIAZOLYL)-3-ETHYL-2-(-(METHY;Akt Inhibitor IV - CAS 681281-88-9 - Calbiochem;6-(2-Benzothiazolyl)-1-ethyl-2-[2-(methylphenylamino)ethenyl]-3-phenyl-1H-benzimidazolium iodide;6-benzothiazol-2-yl-1-ethyl-2-[2-(methyl-phenyl-amino)-vinyl]-3-phenyl-3H-benzoimidazol-1-ium iodide;5-(Benzo[d]thiazol-2-yl)-3-ethyl-2-(2-(methyl(phenyl)amino)vinyl)-1-phenyl-1H-benzo[d]imidazol-3-ium iodide;(E)-5-(benzo[d]thiazol-2-yl)-3-ethyl-2-(2-(methyl(phenyl)amino)vinyl)-1-phenyl-1H-benzo[d]imidazol-3-ium iodide
- CBNumber:
- CB5497911
- Molecular Formula:
- C31H27N4S.I
- Molecular Weight:
- 614.548
- MDL Number:
- MFCD00570739
- MOL File:
- 681281-88-9.mol
- MSDS File:
- SDS
Last updated:2023-06-08 09:02:15
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H335-H319-H315 | |||||||||
| Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| NFPA 704 |
|
5-(2-BENZOTHIAZOLYL)-3-ETHYL-2-(-(METHY price More Price(22)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 124011 | Akt Inhibitor IV | 681281-88-9 | 1mg | $172 | 2024-03-01 | Buy |
| Sigma-Aldrich | 124011 | Akt Inhibitor IV | 681281-88-9 | 5mg | $619 | 2024-03-01 | Buy |
| Cayman Chemical | 15569 | Akt Inhibitor IV ≥95% | 681281-88-9 | 1mg | $40 | 2024-03-01 | Buy |
| Cayman Chemical | 15569 | Akt Inhibitor IV ≥95% | 681281-88-9 | 5mg | $177 | 2024-03-01 | Buy |
| Sigma-Aldrich | B2311 | 5-(2-Benzothiazolyl)-3-ethyl-2-[2-(methylphenylamino)ethenyl]-1-phenyl-1H-benzimidazolium iodide ≥98% (HPLC) | 681281-88-9 | 5mg | $205 | 2024-03-01 | Buy |
5-(2-BENZOTHIAZOLYL)-3-ETHYL-2-(-(METHY Chemical Properties,Uses,Production
Uses
Akt Inhibitor IV is an Inhibitor of Akt protein kinase
Biological Activity
akt inhibitor iv is an inhibitor of akt activation that inhibits akt-mediated nuclear export of forkhead box class o transcription factor 1a (foxo1a; ic50 = 625 nm) and reduces phosphorylation of akt at ser473 and thr308 in a dose-dependent manner. akt inhibitor iv inhibits replication of parainfluenza virus 5 (piv5) in hela cells (ic50 = 520 nm). it also reduces the growth of cancer cells (ic50 = 0.3 μm for both jurkat and hela cells) via a reduction in mitochondrial polarization and increased production of reactive oxygen species (ros).
5-(2-BENZOTHIAZOLYL)-3-ETHYL-2-(-(METHY Preparation Products And Raw materials
Raw materials
Preparation Products
5-(2-BENZOTHIAZOLYL)-3-ETHYL-2-(-(METHY Suppliers
Global( 35)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| LEAP CHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 24738 | 58 |
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | trendseenbio@gmail.com | China | 11681 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8474 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| Shanghai Witofly Chemical Co.,Ltd | sales@witofly.com | China | 2867 | 52 | |
| Qingdao Kingway Pharmtech Co., Ltd. | 0532-87118899 | sales@kingwaypharm.com | China | 119 | 56 |
| Hubei XinyuanShun Chemical Co., Ltd. | 13971561712, 13995564702, 027-50664929 | hbeixys2001@163.com | China | 3123 | 55 |
| Beijing Autumn Biomedical Technology Co., Ltd | 010-80828512 18001163873 | China | 58 | 55 | |
| Shanghai Synchem Pharma Co., ltd | 21-619849051-1 18521059765 | synchempharma@aliyun.com | China | 6457 | 55 |
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 | sales@glpbio.cn | China | 6870 | 58 |
(E)-5-(benzo[d]thiazol-2-yl)-3-ethyl-2-(2-(methyl(phenyl)amino)vinyl)-1-phenyl-1H-benzo[d]imidazol-3-ium iodide
6-benzothiazol-2-yl-1-ethyl-2-[2-(methyl-phenyl-amino)-vinyl]-3-phenyl-3H-benzoimidazol-1-ium iodide
5-(Benzo[d]thiazol-2-yl)-3-ethyl-2-(2-(methyl(phenyl)amino)vinyl)-1-phenyl-1H-benzo[d]imidazol-3-ium iodide
6-(2-Benzothiazolyl)-1-ethyl-2-[2-(methylphenylamino)ethenyl]-3-phenyl-1H-benzimidazolium iodide
5-(2-BENZOTHIAZOLYL)-3-ETHYL-2-(-(METHY
Akt Inhibitor IV - CAS 681281-88-9 - Calbiochem
681281-88-9
C31H27N4SI