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Bromamphenicol
- CAS No.
- 17371-30-1
- Chemical Name:
- Bromamphenicol
- Synonyms
- R-(R*,R*)]-2,2-dibromo-N-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]-acetamide;Acetamide, 2,2-dibromo-N-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]-, [R-(R*,R*)]- (9CI)
- CBNumber:
- CB55540906
- Molecular Formula:
- C11H12Br2N2O5
- Molecular Weight:
- 412.03
- MDL Number:
- MOL File:
- 17371-30-1.mol
Last updated:2023-05-21 10:59:17
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Bromamphenicol Chemical Properties,Uses,Production
Description
Bromamphenicol is a dibrominated derivative of the antibiotic chloramphenicol.1 It inhibits rat liver mitochondrial and E. coli protein synthesis by 90.6 and 98.8%, respectively, when used at a concentration of 93 μM, and inhibits DNA synthesis in human lymphoblastoid cells by 83% at 1 mM. Bromamphenicol can also bind to the major adhesin subunit DraE from E. coli.2
References
1. Manyan, D.R., Arimura, G.K., and Yunis, A.A. Comparative metabolic effects of chloramphenicol analogues Mol. Pharmacol. 11(5),520-527(1975).
2. Pettigrew, D.M., Roversi, P., Davies, S.G., et al. A structural study of the interaction between the Dr haemagglutinin DraE and derivatives of chloramphenicol Acta Crystallogr. D Biol. Crystallogr. 65(Pt 6),513-522(2009).
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Global( 6)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
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Shanghai Yiyan Biotechnology Co. , Ltd. | 021-69985186 13611928337 | 3427709316@qq.com | China | 7979 | 58 |
Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11975 | 58 |
Acetamide, 2,2-dibromo-N-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]-, [R-(R*,R*)]- (9CI)
R-(R*,R*)]-2,2-dibromo-N-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]-acetamide
17371-30-1