ChemicalBook >> CAS DataBase List >>K811

K811

CAS No.
1355228-38-4
Chemical Name:
K811
Synonyms
K811;3-Quinolinecarboxamide, N-[4-[(6,7-dimethoxy-4-cinnolinyl)oxy]phenyl]-1,4-dihydro-1-(1-methylethyl)-4-oxo-
CBNumber:
CB55838153
Molecular Formula:
C29H26N4O5
Molecular Weight:
510.54
MDL Number:
MFCD32697116
MOL File:
1355228-38-4.mol
Last updated:2023-03-31 09:12:57

K811 Properties

Density 1.326±0.06 g/cm3(Predicted)
pka 11.33±0.70(Predicted)

K811 Chemical Properties,Uses,Production

Description

K811 is an ASK1-specific inhibitor that prolongs survival in a mouse model of amyotrophic lateral sclerosis. K811 efficiently prevented cell proliferation in cell lines with high ASK1 expression and in HER2-overexpressing GC cells. Treatment with K811 reduced sizes of xenograft tumors by downregulating proliferation markers.

K811 Preparation Products And Raw materials

Raw materials

Preparation Products

K811 Suppliers

Global( 3)Suppliers
Supplier Tel Email Country ProdList Advantage
ShangHai Caerulum Pharma Discovery Co., Ltd. 18149758185 sales-cpd@caerulumpharma.com China 3460 58
https://hanhongsci.com/ 021-54306202 18917919676 info@hanhongsci.com China 29990 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 28118 58
K811 3-Quinolinecarboxamide, N-[4-[(6,7-dimethoxy-4-cinnolinyl)oxy]phenyl]-1,4-dihydro-1-(1-methylethyl)-4-oxo- 1355228-38-4