N-Biotinyl-N'-(iodoacetyl)-1,6-hexanediaMine
- CAS No.
- 93285-75-7
- Chemical Name:
- N-Biotinyl-N'-(iodoacetyl)-1,6-hexanediaMine
- Synonyms
- Iaa-Biotin;IODOACETYL LC BIOTIN;Biotin-C6-iodoacetamide;N-IODOACETYL-N-BIOTINYLHEXYLENEDIAMINE;N-IODOACETYL-N'-BIOTINYLHEXYLENEDIAMINE;N-Iodoacetyl-N'-biotinyl-1,6-hexanediamine;N-BIOTINYL-N'-(IODOACETYL)-1,6-HEXANEDIAMINE;N-Biotinyl-Na€-(iodoacetyl)-1,6-hexanediamine;N-Iodoacetyl-N-biotinylhexylenediaMine(Iodoacetyl-LC-Biotin);(3aS,4S,6aR)-Hexahydro-N-[6-[(iodoacetyl)amino]hexyl]-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanamide
- CBNumber:
- CB5664328
- Molecular Formula:
- C18H31IN4O3S
- Molecular Weight:
- 510.43
- MDL Number:
- MFCD00054987
- MOL File:
- 93285-75-7.mol
| Boiling point | 793.7±60.0 °C(Predicted) |
|---|---|
| Density | 1.414±0.06 g/cm3 (20 ºC 760 Torr) |
| storage temp. | Sealed in dry,2-8°C |
| solubility | ≥51 mg/mL in DMSO with gentle warming; insoluble in EtOH; insoluble in H2O |
| form | solid |
| pka | 13.90±0.40(Predicted) |
| color | White to off-white |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P271-P280-P304+P340 |
| Hazard Codes | Xi |
| HS Code | 2928009090 |
N-Biotinyl-N'-(iodoacetyl)-1,6-hexanediaMine price More Price(9)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | B396025 | N-Biotinyl-N’-(iodoacetyl)-1,6-hexanediamine | 93285-75-7 | 50mg | $560 | 2021-12-16 | Buy |
| BroadPharm | BP-22638 | Iodoacetyl-LC-Biotin 97% | 93285-75-7 | 250mg | $560 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | HCH0009003 | N-IODOACETYL-N-BIOTINYLHEXYLENEDIAMINE 95.00% | 93285-75-7 | 100MG | $715.75 | 2021-12-16 | Buy |
| ApexBio Technology | A8009 | Iodoacetyl-LC-Biotin | 93285-75-7 | 100mg | $185 | 2021-12-16 | Buy |
| BroadPharm | BP-22638 | Iodoacetyl-LC-Biotin 97% | 93285-75-7 | 100mg | $280 | 2021-12-16 | Buy |
N-Biotinyl-N'-(iodoacetyl)-1,6-hexanediaMine Chemical Properties,Uses,Production
Description
iodoacetyll-LC-Biotin is a sulfhydryl-reactive biotinylation reagent that forms stable, irreversible thioether bonds when reacting with with sulfhydryls (-SH) group at alkaline pH. The hexylenediamine spacer arm gives this reagent the membrane-impermeability which enables intracellular labeling of biomolecules.
Uses
N-Biotinyl-N'-(iodoacetyl)-1,6-hexanediaMine can be a useful reagent for biotinylation of proteins and subsequent use in a protein microarray.
Uses
amine reactive biotinylation reagent
Biological Activity
iodoacetyl-lc-biotin (n-iodoacetyl-n-biotinylhexylenediamine), a sulfhydryl-reactive biotinylation agent, is a water-insoluble reagent that requires the dissolution of suitable solvents, including dimethyl sulfoxide (dmso) and dimethylformamide (dmf), prior to the addition into aqueous reactions. iodoacetyl-lc-biotin consists of a bicyclic biotin rings structure, a 1,6-diaminohexane spacer group attached to the valeric acid side chain of biotin and an iodoacetyl group at the end of the spacer providing sulfhydryl reactivity. the iodoacetyl group at the end of iodoacetyl-lc-biotin is able to react with sulfhydryl groups on proteins and other molecules forming a nonreversible bond. the long spacer arm of iodoacetyl-lc-biotin enables the modified molecule to better bind to the avidin or streptavidin probes.bioconjugate techniques , 2nd ed. by greg t.hermanson (pierce biotechnology, thermo fisher scientific, rockford, il). academic press (an imprint of elsevier): london, amsterdam, burlington, san diego . 2008. isbn 978-0-12-370501-3.
N-Biotinyl-N'-(iodoacetyl)-1,6-hexanediaMine Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32161 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49734 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42056 | 58 |
| Xian confluore Biological Technology Co., Ltd. | +86-15680926068 +86-15680926068 | 1924344760@confluore.cn | China | 2996 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 52924 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15839 | 69 |
| Chemsky (shanghai) International Co.,Ltd | 021-50135380 | shchemsky@sina.com | China | 15402 | 60 |
| Spectrum Chemical Manufacturing Corp. | 021-021-021-67601398-809-809-809 15221380277 | marketing_china@spectrumchemical.com | China | 9658 | 60 |
| Hangzhou Sage Chemical Co., Ltd. | +86057186818502 13588463833 | info@sagechem.com | China | 10266 | 58 |
View Lastest Price from N-Biotinyl-N'-(iodoacetyl)-1,6-hexanediaMine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-02 | Biotin-C6-iodoacetamide
93285-75-7
|
US $0.00 / mg | 250mg | >95.00% | 250mg | Xian confluore Biological Technology Co., Ltd. |
-
- Biotin-C6-iodoacetamide
93285-75-7
- US $0.00 / mg
- >95.00%
- Xian confluore Biological Technology Co., Ltd.
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