Nandrolone
- CAS No.
- 434-22-0
- Chemical Name:
- Nandrolone
- Synonyms
- 19-NORTESTOSTERONE;nortestosterone;NANDROLON;Nandrolone Base;NADROLONE;Nandrolone decanoat;C07254;NSC 3351;ndrolone;menidrabol
- CBNumber:
- CB5681525
- Molecular Formula:
- C18H26O2
- Molecular Weight:
- 274.4
- MDL Number:
- MFCD00003664
- MOL File:
- 434-22-0.mol
| Melting point | 120-125 °C |
|---|---|
| alpha | D22 +55° (c = 0.93 in chloroform) |
| Boiling point | 357.38°C (rough estimate) |
| Density | 1.0528 (rough estimate) |
| refractive index | 1.4800 (estimate) |
| Flash point | 2℃ |
| storage temp. | Controlled Substance, -20°C Freezer |
| solubility | Acetonitrile: 1 mg/ml; Ethanol: 1 mg/ml; Methanol: 1 mg/ml |
| form | A crystalline solid |
| pka | 15.06±0.40(Predicted) |
| color | Dimorphic crystals from CH2Cl2/Et2O |
| Water Solubility | 3.09g/L(25 ºC) |
| Merck | 6365 |
| BRN | 2055849 |
| InChIKey | NPAGDVCDWIYMMC-IZPLOLCNSA-N |
| CAS DataBase Reference | 434-22-0(CAS DataBase Reference) |
| FDA UNII | 6PG9VR430D |
| NIST Chemistry Reference | Nandrolone(434-22-0) |
| ATC code | A14AB01,S01XA11 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H351-H360FD | |||||||||
| Precautionary statements | P201-P202-P280-P308+P313-P405-P501 | |||||||||
| Hazard Codes | Xn,T,F | |||||||||
| Risk Statements | 20/21/22-64-40-61-60-36-11-38-19 | |||||||||
| Safety Statements | 22-24/25-36/37/39-45-36/37-53-16 | |||||||||
| RIDADR | UN 1648 3 / PGII | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | KG7964000 | |||||||||
| HS Code | 29372900 | |||||||||
| NFPA 704 |
|
Nandrolone price More Price(16)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | N-050 | Nandrolone solution 1.0?mg/mL in acetonitrile, ampule of 1?mL, certified reference material, Cerilliant? | 434-22-0 | 1mL | $170 | 2024-03-01 | Buy |
| Sigma-Aldrich | BP257 | Nandrolone British Pharmacopoeia (BP) Reference Standard | 434-22-0 | 100MG | $255 | 2024-03-01 | Buy |
| Sigma-Aldrich | 1454008 | Nandrolone United States Pharmacopeia (USP) Reference Standard | 434-22-0 | 50mg | $953 | 2024-03-01 | Buy |
| Cayman Chemical | 21173 | Nandrolone ≥98% | 434-22-0 | 1mg | $38 | 2024-03-01 | Buy |
| Cayman Chemical | 21173 | Nandrolone ≥98% | 434-22-0 | 5mg | $93 | 2024-03-01 | Buy |
Nandrolone Chemical Properties,Uses,Production
Chemical Properties
Crystalline Solid
Originator
Durabolin,Organon,US,1959
Uses
An anabolic steroid. Controlled substance (anabolic steroid)
Definition
ChEBI: A 3-oxo Delta4-steroid that is estr-4-en-3-one substituted by a beta-hydroxy group at position 17.
Manufacturing Process
An ice-cold solution of 1.5 grams of 19-nortestosterone and 1.5 ml of dry pyridine in 10 ml of dry benzene is prepared and a solution of 1.5 ml of β- phenylpropionyl chloride in 5 ml of dry benzene is added dropwise over a period of about 2 minutes with stirring. The resulting mixture is allowed to stand overnight under an atmosphere of nitrogen and then washed successively with cold 5% aqueous hydrochloric acid solution, cold 2.5% aqueous sodium hydroxide solution, and water. After drying over anhydrous sodium sulfate, the solvent is evaporated to give an almost colorless oil. Recrystallization from methanol gives white crystals of 19-nortestosterone 17- β-phenylpropionate, MP 91° to 92.5°C.
Therapeutic Function
Anabolic
Mechanism of action
Nandrolone facilitates formation of body muscle mass and strengthens the process of osseous tissue development. The main indications for using nandrolone, as well as other anabolic steroids, are abnormal protein anabolism, asthenia, diseases accompanied by protein loss, adrenal insufficiency, steroid diabetes, and prolonged condition of sluggishness.
Safety Profile
Experimental reproductiveeffects. When heated to decomposition it emits acridsmoke and irritating fumes.
Synthesis
Nandrolone, 17|?-hydroxyester-4-en-3-one (29.1.7), is made from estradiol (28.1.17). The phenol hydroxyl group undergoes methylation by dimethylsulfate in the presence of sodium hydroxide, forming the corresponding methyl ether (29.3.1), and then the aromatic ring is reduced by lithium in liquid ammonia, which forms an enol ether (29.3.2). Hydrolyzing this compound with a mixture of hydrochloric and acetic acids leads to the formation of a keto group, and simultaneous isomerization of the double bond from C5¨CC10 to position C4¨CC5 gives the desired nandrolone (29.3.3) [16¨C19]. Upon necessity of using it in the form of acid esters, the product is acylated by corresponding acid derivatives.
Nandrolone Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10473 | 58 |
| Shandong Huisheng Import & Export Co., Ltd. | +86-13176845580 +86-13176845580 | da@zhongda-biotech.com | China | 232 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | 18192627656 | 1012@dideu.com | China | 3002 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12837 | 58 |
| Anhui Zhongda Biotechnology Co., Ltd | +8619956560829 | justine@zhongda-biotech.com | China | 286 | 58 |
| Anhui Zhongda Biotechnology Co., Ltd | +8615689548120 | linda@zhongda-biotech.com | China | 193 | 58 |
| Anhui Ruihan Technology Co., Ltd | +8617756083858 | daisy@anhuiruihan.com | China | 973 | 58 |
| zhuzhou dingcheng meihei comestic co.,ltd | +8618873369619 | dingchengbusiness8@163.com | China | 260 | 58 |
| Hebei Kangcang new material Technology Co., LTD | +8615713292910 | Nancy@kangcang.com.cn | China | 341 | 58 |
| hebei hongtan Biotechnology Co., Ltd | +86-86-1913198-3935 +8617331935328 | sales03@chemcn.cn | China | 970 | 58 |
View Lastest Price from Nandrolone manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-05 | Nandrolone base
434-22-0
|
US $30.00 / kg | 1kg | 98% | 2000kg | hebei hongtan Biotechnology Co., Ltd | |
 |
2024-10-23 | Nandrolone
434-22-0
|
US $230.00 / kg | 1kg | 99% | 1000kg | Wuhan Cell Pharmaceutical Co., Ltd | |
 |
2024-10-18 | Nandrolone
434-22-0
|
US $25.00 / Box | 1Box | 99.99% | 10000000000 | zhuzhou dingcheng meihei comestic co.,ltd |
-
- Nandrolone base
434-22-0
- US $30.00 / kg
- 98%
- hebei hongtan Biotechnology Co., Ltd
-
- Nandrolone
434-22-0
- US $230.00 / kg
- 99%
- Wuhan Cell Pharmaceutical Co., Ltd
-
- Nandrolone
434-22-0
- US $25.00 / Box
- 99.99%
- zhuzhou dingcheng meihei comestic co.,ltd