H-ARG-ARG-ARG-ARG-ARG-ARG-ARG-ARG-ARG-OH
- CAS No.
- 143413-47-2
- Chemical Name:
- H-ARG-ARG-ARG-ARG-ARG-ARG-ARG-ARG-ARG-OH
- Synonyms
- (ARG)9;RRRRRRRRR;Peptide R9;R 9 peptide;Nonaarginine;(Arg)9 peptide;H-RRRRRRRRR-NH2;Poly Arginine 9;Nona-L-arginine;R9/Nonaarginine
- CBNumber:
- CB5706464
- Molecular Formula:
- C54H110N36O10
- Molecular Weight:
- 1423.69
- MDL Number:
- MFCD08458590
- MOL File:
- 143413-47-2.mol
- MSDS File:
- SDS
Density | 1.60±0.1 g/cm3(Predicted) |
---|---|
storage temp. | Store at -20°C |
solubility | Soluble in DMSO |
Sequence | H-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-OH |
FDA UNII | PK7O6W0U44 |
H-ARG-ARG-ARG-ARG-ARG-ARG-ARG-ARG-ARG-OH price
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Aaron Chemicals | AR009BQF | H-ARG-ARG-ARG-ARG-ARG-ARG-ARG-ARG-ARG-OH 97% | 143413-47-2 | 100mg | $220 | 2021-12-16 | Buy |
Aaron Chemicals | AR009BQF | H-ARG-ARG-ARG-ARG-ARG-ARG-ARG-ARG-ARG-OH 97% | 143413-47-2 | 250mg | $326 | 2021-12-16 | Buy |
H-ARG-ARG-ARG-ARG-ARG-ARG-ARG-ARG-ARG-OH Chemical Properties,Uses,Production
Biological Activity
(Arg)9 (Nona-L-arginine; Peptide R9) is a cell-permeable polypeptide with IC50 value of 0.78 μM for neuroprotection in a glutamate model experimental model.
in vitro
Poly-arginine (eg (Arg)9) and arginine-rich peptides (eg TAT, penetratin), which belong to a class of peptides with cell-penetrating properties are neuroprotective. It provides significant neuroprotection in a dose–response manner following glutamic acid exposure (IC 50 =0.78 μM). Following kainic acid exposure, (Arg)9 is neuroprotective, but less effective than in the glutamic acid model (IC 50 =0.81 μM). (Arg)9 also shows neuroprotection following in vitro ischemia (IC 50 =6 μM).
in vivo
(Arg)9) (D-isoform) is neuroprotective in rat stroke models. (Arg)9) is highly neuroprotective, with efficacy increasing with increasing arginine content, has the capacity to reduce glutamic acid-induced neuronal calcium influx and requires heparan sulfate preotoglycan-mediated endocytosis to induce a neuroprotective effect. (Arg)9) (D-isoform) administered intravenously at a dose of 1000 nmol/kg 30 min after reduces permanent middle cerebral artery occlusion (MCAO) infarct volume .
target
IC50: 0.78 μM (neuroprotection)
H-ARG-ARG-ARG-ARG-ARG-ARG-ARG-ARG-ARG-OH Preparation Products And Raw materials
Raw materials
Preparation Products
H-ARG-ARG-ARG-ARG-ARG-ARG-ARG-ARG-ARG-OH Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10311 | 58 |
BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29824 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10522 | 58 |
Hangzhou Go Top Peptide Biotech | 0571-88211921 | sales1@gotopbio.com | CHINA | 2609 | 58 |
Henan Alfa Chemical Co., Ltd | +8618339805032 | alfa4@alfachem.cn | China | 13183 | 58 |
Alfa Chemistry | Info@alfa-chemistry.com | United States | 24072 | 58 | |
Chengdu Youngshe Chemical Co., Ltd. | +8618108235634 | Cecilia@youngshechem.com | China | 2345 | 58 |
LEAP CHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 24738 | 58 |
View Lastest Price from H-ARG-ARG-ARG-ARG-ARG-ARG-ARG-ARG-ARG-OH manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2020-02-14 | H-ARG-ARG-ARG-ARG-ARG-ARG-ARG-ARG-ARG-OH
143413-47-2
|
US $7.00 / KG | 1KG | 99% | 100kg | Career Henan Chemical Co |
- H-ARG-ARG-ARG-ARG-ARG-ARG-ARG-ARG-ARG-OH
143413-47-2
- US $7.00 / KG
- 99%
- Career Henan Chemical Co
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