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GUANABENZ HYDROCHLORIDE

CAS No.
23113-43-1
Chemical Name:
GUANABENZ HYDROCHLORIDE
Synonyms
NE56490;GUANABENZ HYDROCHLORIDE;Guanabenzhydrochloride(Wytensin);1-{[(2,6-Dichlorophenyl)methylidene]amino}guanidine Hydrochloride;2-(2,6-Dichlorobenzylidene)hydrazine-1-carboximidamide hydrochloride;Hydrazinecarboximidamide, 2-(2,6-dichlorobenzylidene)-, hydrochloride;inhibit,Guanabenz hydrochloride,antiparasitic,Inhibitor,Beta Receptor,Guanabenz,Parasite,Adrenergic Receptor,antihypertensive,high blood pressure
CBNumber:
CB5738700
Molecular Formula:
C8H9Cl3N4
Molecular Weight:
267.54
MDL Number:
MFCD01722581
MOL File:
23113-43-1.mol
Last updated:2024-07-02 08:55:11

GUANABENZ HYDROCHLORIDE Properties

storage temp. Store at -20°C
solubility ≥4.3 mg/mL in H2O; ≥4.37 mg/mL in EtOH; ≥9.25 mg/mL in DMSO
form A crystalline solid
color White to off-white
EWG's Food Scores 1

GUANABENZ HYDROCHLORIDE price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 10851 Guanabenz (hydrochloride) ≥98% 23113-43-1 25mg $45 2024-03-01 Buy
Cayman Chemical 10851 Guanabenz (hydrochloride) ≥98% 23113-43-1 50mg $85 2024-03-01 Buy
Cayman Chemical 10851 Guanabenz (hydrochloride) ≥98% 23113-43-1 100mg $160 2024-03-01 Buy
TRC B419480 1-{[(2,6-Dichlorophenyl)methylidene]amino}guanidineHydrochloride 23113-43-1 250mg $90 2021-12-16 Buy
ApexBio Technology C3786 Guanabenz(hydrochloride) 23113-43-1 50mg $95 2021-12-16 Buy
Product number Packaging Price Buy
10851 25mg $45 Buy
10851 50mg $85 Buy
10851 100mg $160 Buy
B419480 250mg $90 Buy
C3786 50mg $95 Buy

GUANABENZ HYDROCHLORIDE Chemical Properties,Uses,Production

Description

Guanabenz is an α2-adrenergic receptor agonist (effective concentrations 10-100 nM) with hypotensive effects. It also competes for imidazoline I2-binding sites in brown adipose tissue (Ki = 97 nM).

in vitro

maximum concentrations of guanabenz in plasma (1.2 to 5.2 ng/ml) reached 2 to 5 hours after administration of capsules containing 16 or 32 mg of 14c-labelled guanabenz. guanabenz was 90% bound to human plasma proteins [1]. guanabenz competed for imidazoline i2-binding sites in brown adipose tissue with ki of 97 nm [3].

References

[1] holmes b, brogden r n, heel r c, et al. guanabenz[j]. drugs, 1983, 26(3): 212-229.
[2] aantaa r, marjam ki a, scheinin m. molecular pharmacology of α2-adrenoceptor subtypes[j]. annals of medicine, 1995, 27(4): 439-449.
[3] rmer l, wurster s, savola j m, et al. identification and characterization of the imidazoline i2b-binding sites in the hamster brown adipose tissue as a study model for imidazoline receptors[j]. archives of physiology and biochemistry, 2003, 111(2): 159-166.

GUANABENZ HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

GUANABENZ HYDROCHLORIDE Suppliers

Global( 31)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
LEAPCHEM CO., LTD.
+86-852-30606658 market18@leapchem.com China 43348 58
Aladdin Scientific
+1-+1(833)-552-7181 sales@aladdinsci.com United States 52927 58
BOC Sciences 16314854226 info@bocsci.com United States 9926 65
Tianjin Kailiqi Biotechnology Co., Ltd. 15076683720 klq@cw-bio.com China 3552 55
Shanghai Latchem Co., Ltd. 021-61916491 15921747686 sales@latcheminc.com China 986 58
Shanghai Haohong Pharmaceutical Co., Ltd. 400-8210725 4008210725 malulu@leyan.com China 39997 58
Bide Pharmatech Ltd. 400-1647117 15221909166 product02@bidepharm.com China 63720 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24017 58
Shaoguan Qicheng Biotechnology Co., Ltd 18122215013 780229652@qq.com China 955 58

23113-43-1(GUANABENZ HYDROCHLORIDE)Related Search:

GUANABENZ HYDROCHLORIDE Hydrazinecarboximidamide, 2-(2,6-dichlorobenzylidene)-, hydrochloride 1-{[(2,6-Dichlorophenyl)methylidene]amino}guanidine Hydrochloride Guanabenzhydrochloride(Wytensin) NE56490 inhibit,Guanabenz hydrochloride,antiparasitic,Inhibitor,Beta Receptor,Guanabenz,Parasite,Adrenergic Receptor,antihypertensive,high blood pressure 2-(2,6-Dichlorobenzylidene)hydrazine-1-carboximidamide hydrochloride 23113-43-1 C8H8Cl2N4HCl