Sesamin | 607-80-7

Sesamin Properties

Melting point	121.0 to 125.0 °C
Boiling point	504.4±50.0 °C(Predicted)
Density	1.385±0.06 g/cm3(Predicted)
storage temp.	-20°C
solubility	Soluble in DMSO (>25 mg/ml)
form	crystalline
color	White
Merck	14,8470
Stability	Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
InChIKey	PEYUIKBAABKQKQ-AFHBHXEDSA-N
LogP	4.064 (est)
FDA UNII	S7946O4P76

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H317

Precautionary statements

P261-P272-P280-P302+P352-P333+P313-P362+P364

Safety Statements

22-24/25

WGK Germany

3

HS Code

29329990

NFPA 704

	1
0		0

Sesamin price More Price(32)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	59867	Sesamin analytical standard	607-80-7	10mg	$229	2024-03-01	Buy
Sigma-Aldrich	SMB00705	Sesamin ≥98% (HPLC)	607-80-7	10MG	$221	2023-06-20	Buy
Sigma-Aldrich	SMB00705	Sesamin ≥98% (HPLC)	607-80-7	50MG	$815	2023-06-20	Buy
Sigma-Aldrich	S9314	Sesamin ≥95%, crystalline	607-80-7	5mg	$436	2022-05-15	Buy
TCI Chemical	S0495	Sesamin >98.0%(GC)	607-80-7	100mg	$362	2024-03-01	Buy

Product number	Packaging	Price	Buy
59867	10mg	$229	Buy
SMB00705	10MG	$221	Buy
SMB00705	50MG	$815	Buy
S9314	5mg	$436	Buy
S0495	100mg	$362	Buy

Sesamin Chemical Properties,Uses,Production

Description

Sesamin (607-80-7) is a natural product derived from sesame seeds with anticancer1, antioxidant2, anti-inflammatory/immunomodulatory3, and antidiabetic4,5 effects. It also displayed effects on cholesterol and fatty acid metabolism.6? Sesamin was recently found to inhibit bacterial L-tryptophan indole lyase (Ki = 7 μM).7 This enzyme reacts with dietary tryptophan to produce the uremic toxin indoxyl sulfate which exacerbates chronic kidney disease.

Chemical Properties

White powder

Uses

Sesamin has been used:

as a lignan to study its effects on the osteoblastic differentiation of rat bone marrow stromal cells (BMSCs)
as a standard for the isolation of sesamin from sesame oil
as an enterolignan to study its effects on the proliferation of estrogen-receptor (ER)-positive human breast cancer MCF-7 cells

Uses

A lignan isolated from the bark of Fagara plants and from sesame oil. Studies show that it has has multiple functions such as cholesterol-lowering and anti-hypertensive activities. It induces the expr ession of the gene for aldehyde dehydrogenase, an alcohol-metabolizing enzyme suggesting it regulates the metabolism of lipids, xenobiotics, and alcohol at the mRNA level.

Definition

ChEBI: A lignan that consists of tetrahydro-1H,3H-furo[3,4-c]furan substituted by 1,3-benzodioxole groups at positions 1 and 4 (the 1S,3aR,4S,6aR

General Description

Sesamin is a fat-soluble furfuran lignan present in Sesamum indicum?L seeds.

Biochem/physiol Actions

Non-competitive Δ5-desaturase inhibitor.

References

Majdalawieh et al. (2017) A comprehensive review on the anti-cancer properties and mechanisms of action of sesamin, a lignan in sesame seeds (Sesamum indicum); Eur.? J. Pharmacol.?815 512 Kiso (2004) Antioxidative role of sesamin, a functional lignan in sesame seed, and its effect on lipid- and alcohol-metabolism in the liver: a DNA microarray study; Biofactors 21 191 Majdalawieh et al. (2021) Immunomodulatory and anti-inflammatory effects of sesamin: mechanisms of action and future directions; Crit.? Rev. Food Sci. Nutr.?5 1 Shahi et al. (2017) Effect of Sesamin Supplementation on Glycemic Status, Inflammatory Markers, and Adiponectin Levels in Patients with Type 2 Diabetes Mellitus; J. Diet. Suppl.?14 65 Farbood et al. (2019) Sesamin: A promising protective agent against diabetes-associated cognitive decline in rats; Life Sci. 230 169 Majdalawieh et al. (2020) Effects of sesamin on fatty acid and cholesterol metabolism, macrophage cholesterol homeostasis and serum lipid profile: a comprehensive review; Eur. J. Pharmacol. 173417 Oikawa et al. (2022) (+)-Sesamin, a sesame lignan, is a potent inhibitor of gut bacterial tryptophan indole-lyase that is a key enzyme in chronic kidney disease pathogenesis; Biochem. Biophys. Res. Commun.?590 158

Sesamin Preparation Products And Raw materials

Raw materials

Preparation Products

Sesamin Suppliers

Global( 403)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Mojin Biotechnology Co., Ltd	+86 13288715578 +8613288715578	sales@hbmojin.com	China	12839	58
Wuhan Haorong Biotechnology Co.,ltd	+86-18565342920; +8618565342920	sales@chembj.net	China	289	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21634	55
Hangzhou FandaChem Co.,Ltd.	+8615858145714	FandaChem@Gmail.com	China	9206	55
Shanghai Zheyan Biotech Co., Ltd.	18017610038	zheyansh@163.com	CHINA	3619	58
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29881	58
Shaanxi Yikanglong Biotechnology Co., Ltd.	17791478691	yklbiotech@163.com	CHINA	296	58
Chengdu Biopurify Phytochemicals Ltd.	+8618080483897	sales@biopurify.com	China	3772	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19553	58
Chongqing Chemdad Co., Ltd	+86-023-6139-8061 +86-86-13650506873	sales@chemdad.com	China	39894	58

Supplier	Advantage
Hebei Mojin Biotechnology Co., Ltd	58
Wuhan Haorong Biotechnology Co.,ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
Hangzhou FandaChem Co.,Ltd.	55
Shanghai Zheyan Biotech Co., Ltd.	58
career henan chemical co	58
Shaanxi Yikanglong Biotechnology Co., Ltd.	58
Chengdu Biopurify Phytochemicals Ltd.	58
BOC Sciences	58
Chongqing Chemdad Co., Ltd	58

View Lastest Price from Sesamin manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-11-28	Sesamin powder 607-80-7	US $0.00-0.00 / g	1g	98%	2000	Changsha Staherb Natural Ingredients Co., Ltd.
2024-11-27	Sesamin 607-80-7	US $0.00-0.00 / kg	20kg	99%	200000	Wuhan Haorong Biotechnology Co.,Ltd
2024-11-21	Sesame Extract, Sesamin 607-80-7	US $0.00 / Kg/Bag	1T	98%	10 tons	Hengshui Haoye Co.,Ltd.

Sesamin powder
607-80-7
US $0.00-0.00 / g
98%
Changsha Staherb Natural Ingredients Co., Ltd.

Sesamin
607-80-7
US $0.00-0.00 / kg
99%
Wuhan Haorong Biotechnology Co.,Ltd

Sesame Extract, Sesamin
607-80-7
US $0.00 / Kg/Bag
98%
Hengshui Haoye Co.,Ltd.

Sesamin Spectrum

Sesamin(607-80-7)MS Sesamin(607-80-7)IR1 Sesamin(607-80-7)IR2

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1of4

[1S-(1BETA,3ALPHA-BETA,4BETA,6ALPHA-BETA)]-5,5'-(TETRAHYDRO-1H,3H-FURO[3,4-C]FURAN-1,4-DIYL)BIS-1,3-BENZODIOXOLE Sesamine70% SESAMIN(P) SESAMIN(RG) 1,3-Benzodioxole,5,5'-(tetrahydro-1H,3H-furo[3,4-c]furan-1,4-diyl)bis-,[1S-(1α,3aα,4α, 6aα)]- 1,3-Benzodioxole, 5,5'-(tetrahydro-1H,3H-furo[3,4-c]furan-1,4-diyl)bis-, [1S-(1a,3aa,4a,6aa)]- Tetrahydro-1,4-bis[3,4-(methylenedioxy)phenyl]-1H,3H-furo[3,4-c]furan (+)-5,5'-[(1S,3aβ,4S,6aβ)-Tetrahydro-1H,3H-furo[3,4-c]furan-1,4-diyl]-bis-1,3-benzodioxole (+)-5,5'-[(1S,3aβ,4β,6aβ)-Tetrahydro-1H,3H-furo[3,4-c]furan-1,4-diyl]bis(1,3-benzodioxole) d-Sesamin Pseudocubebin SesaMin(Fagarol) NSC 36403 SezaMin (1S,3aR,4S,6aR)-5,5'-(Tetrahydro-1H,3H-furo[3,4-c]furan-1,4-diyl)bis-1,3-benzodioxole (1S,3aR,4S,6aR)-Tetrahydro-1,4-bis[3,4-(Methylenedioxy)phenyl]-1H,3H-Furo[3,4-c]furan [1S-(1α,3aα,4α,6aα)]-5,5'-(Tetrahydro-1H,3H-furo[3,4-c]furan-1,4-diyl)bis-1,3-benzodioxole (+)-SESAMIN SESAMIN SesaMin, froM SesaMuM indicuM 1,3-Benzodioxole,5,5'-(tetrahydro-1H,3H-furo[3,4-c]furan-1,4-diyl)bis-, (1S,3aR,4S,6aR)- Fsesamin Sesamin, >=98% Sesamin, 98%, from Sesamum indicum Sesamin> Sesamin USP/EP/BP Jujube powder Sesame Extract, Sesamin 5-[(3S,3aR,6S,6aR)-3-(1,3-benzodioxol-5-yl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan-6-yl]-1,3-benzodioxole (1S,3aR,4S,6aR)-1,4-Bis(benzo[d][1,3]dioxol-5-yl)hexahydrofuro[3,4-c]furan Sesamin (Fagarol, Fsesamin) Sesamin, ≥95% TIANFU-CHEM -Sesamin (+)-sesamin 3-(1,3-benzodioxol-5-yl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan-6-ol SesameP.E. FAGAROL L-Sesamin Sesamin powder Sesame Extract (Sesamin 90%) Natural Sesamin Powder Abametapir Impurity 28 AI3-00811 Sesamin-RM 607-80-7 C20H15O5 C20H18O6 BioChemical Biochemicals and Reagents D to K Enzyme Inhibitors by Enzyme Enzyme Inhibitors Enzymes, Inhibitors, and Substrates D5-Desaturase Heterocycles Intermediates & Fine Chemicals Pharmaceuticals D5-DesaturaseArachidonic Acid Cascade