ChemicalBook >> CAS DataBase List >>L-Lysinamide, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanyl-L-α-glutamyl-L-asparaginyl- (9CI)
L-Lysinamide, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanyl-L-α-glutamyl-L-asparaginyl- (9CI)
![L-Lysinamide, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanyl-L-α-glutamyl-L-asparaginyl- (9CI) Structure](CAS/20211123/GIF/220701-06-4.gif)
- CAS No.
- 220701-06-4
- Chemical Name:
- L-Lysinamide, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanyl-L-α-glutamyl-L-asparaginyl- (9CI)
- Synonyms
- Fmoc-AENK-NH2;Fmoc-Ala-Glu-Asn-Lys-NH2;L-Lysinamide, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanyl-L-α-glutamyl-L-asparaginyl- (9CI)
- CBNumber:
- CB58401114
- Molecular Formula:
- C33H43N7O9
- Molecular Weight:
- 681.75
- MDL Number:
- MFCD32671948
- MOL File:
- 220701-06-4.mol
Last updated:2024-07-02 08:55:12
L-Lysinamide, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanyl-L-α-glutamyl-L-asparaginyl- (9CI) Properties
| Boiling point | 1151.3±65.0 °C(Predicted) |
|---|---|
| Density | 1.324±0.06 g/cm3(Predicted) |
| storage temp. | -20°C, protect from light, stored under nitrogen |
| solubility | DMSO: 100 mg/mL (146.68 mM; ultrasonic and warming and heat to 80°C) |
| form | Solid |
| pka | 4.44±0.10(Predicted) |
| color | White to off-white |
L-Lysinamide, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanyl-L-α-glutamyl-L-asparaginyl- (9CI) price
L-Lysinamide, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanyl-L-α-glutamyl-L-asparaginyl- (9CI) Chemical Properties,Uses,Production
Biological Activity
Fmoc-Ala-Glu-Asn-Lys-NH2 is a selective asparagine endopeptidase (AEP) inhibitor peptide and suppresses amyloid precursor protein (APP) cleavage. AEP, a pH-controlled cysteine proteinase, is activated during ageing and mediates APP proteolytic processing[1]. Fmoc-Ala-Glu-Asn-Lys-NH2 antagonizes APP processing by AEP, whereas other small molecular inhibitors and inactive peptide AEQK were without effect[1].
References
[1]. Zhang Z, et al. Delta-secretase cleaves amyloid precursor protein and regulates the pathogenesis in Alzheimer's disease. Nat Commun. 2015;6:8762. Published 2015 Nov 9.
L-Lysinamide, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanyl-L-α-glutamyl-L-asparaginyl- (9CI) Preparation Products And Raw materials
Raw materials
Preparation Products
L-Lysinamide, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanyl-L-α-glutamyl-L-asparaginyl- (9CI) Suppliers
Global( 20)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10312 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10522 | 58 |
| Zhejiang Hangyu API Co., Ltd | +8617531972939 | anna@api-made.com | China | 2944 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| Beijing Solarbio Science & Tecnology Co., Ltd. | 010-50973130 4009686088 | 3193328036@qq.com | China | 29786 | 68 |
| Chengdu Youngshe Chemical Co., Ltd. | +86-17380623303 +86-17380623303 | Caroline@youngshechem.com | China | 4905 | 58 |
| Hangzhou Peptidego Biotech Co.,Ltd. | 0571-87213919 | eric@peptidego.com | China | 6526 | 58 |
| Wuxi Helen Biotechnology Co., Ltd., | 0510-85629785 18013409632 | sales@reading-chemicals.com | China | 14081 | 58 |
| Hangzhou Go Top Peptide Biotech | 0571-88211921 13355716090 | Sales@gotopbio.com | China | 2844 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 15801484223; | psaitong@jm-bio.com | China | 29778 | 58 |
220701-06-4(L-Lysinamide, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanyl-L-α-glutamyl-L-asparaginyl- (9CI))Related Search:
FALGPA
KALIOTOXIN
L-659 877
MCA-GLY-LYS-PRO-ILE-LEU-PHE-PHE-ARG-LEU-LYS(DNP)-D-ARG-NH2
Acetyl Pentapeptide-1
1of3
L-Lysinamide, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanyl-L-α-glutamyl-L-asparaginyl- (9CI)
Fmoc-Ala-Glu-Asn-Lys-NH2
Fmoc-AENK-NH2
220701-06-4
C33H43N7O9