morinamide
- CAS No.
- 952-54-5
- Chemical Name:
- morinamide
- Synonyms
- B 2310;morinamide;Morfazinamide;morphazinamide;N-(Morpholinomethyl)-2-pyrazinecarboxamide;2-Pyrazinecarboxamide, N-(4-morpholinylmethyl)-;pyrazine-2-carboxylic acid morpholin-4-ylmethyl-amide
- CBNumber:
- CB5936067
- Molecular Formula:
- C10H14N4O2
- Molecular Weight:
- 222.24
- MDL Number:
- MFCD00868201
- MOL File:
- 952-54-5.mol
| Melting point | 118.5-119.5° |
|---|---|
| FDA UNII | 8CFL28PA3W |
| ATC code | J04AK04 |
morinamide price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | M651765 | Morphazinamide | 952-54-5 | 500mg | $880 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0011982 | MORINAMIDE 95.00% | 952-54-5 | 50MG | $2194.5 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0011982 | MORINAMIDE 95.00% | 952-54-5 | 5MG | $816.75 | 2021-12-16 | Buy |
morinamide Chemical Properties,Uses,Production
Originator
Morinamide,Bracco Industria Chimica S.p.A.
Uses
Morphazinamide is an anti-tuberculosis agent. Also, it is derived from Pyrazinamide (P840600), which is an anti-bacterial (tuberculostatic).
Definition
ChEBI: Morinamide is a member of pyrazines, a secondary carboxamide and a member of morpholines.
Manufacturing Process
98.5 parts by weight 2-pyrazinecarboxamide was mixed with 260 parts by
volume of diethylamine. 91 parts by weight of 37% formaldehyde was added
to above mixture by stirring for 30 minutes. The reaction mixture was
spontaneously heated to 50°C. Then it heated to reflux for 5 hours on water
bath. After that it was distilled to dryness at temperature between 40°-50°C.
The residue was dissolved with about 200 parts by volume of ligroin (B.P.
60°C) by heating. The solution was filtered hot for removing the not reacted
2-pyrazinecarboxamide. Then it was cooled to -10°C and desired N-
(diethylaminomethyl)-pyrazinecarboxylic acid amide discharged. It was filtered
off and recrystallized from light petrol ester. Yield about 90%, MP: 47°-50°C.
500 parts by weight of N-(diethylaminomethyl)pyrazinecarboxylic acid amide
and 2500 parts by volume of was mixed and heated by stirring to temperature
140°-150°C. At 60°-100°C a distillation begun and ended at 127°C (a boiling
point of morpholine). The distillate consisted from diethylamine and
morpholine. After 30-60 minutes the mixture was cooled to 50°C and distilled
in vacuum to dryness. The residue was recrystallized from 400 parts by
volume of benzene to give N-(morpholinomethyl)pyrazinecarboxamide, yield
92%, MP: 114°-117°C.
Therapeutic Function
Antitubercular
morinamide Preparation Products And Raw materials
morinamide Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shaanxi Didu New Materials Co. Ltd | +86-89586680 +86-13289823923 | 1026@dideu.com | China | 8670 | 58 |
| Shaanxi DIDU pharmaceutical and Chemical Co., Ltd | 15229059051 | 1027@dideu.com | China | 9988 | 58 |
| Supplier | Advantage |
|---|---|
| Shaanxi Didu New Materials Co. Ltd | 58 |
| Shaanxi DIDU pharmaceutical and Chemical Co., Ltd | 58 |