ChemicalBook >> CAS DataBase List >>1H-Imidazole-1-ethanol, 2-(ethoxymethyl)-4-iodo-α,α-dimethyl-5-phenyl-
1H-Imidazole-1-ethanol, 2-(ethoxymethyl)-4-iodo-α,α-dimethyl-5-phenyl-
- CAS No.
- 2573912-32-8
- Chemical Name:
- 1H-Imidazole-1-ethanol, 2-(ethoxymethyl)-4-iodo-α,α-dimethyl-5-phenyl-
- Synonyms
- CU-CPD107;1H-Imidazole-1-ethanol, 2-(ethoxymethyl)-4-iodo-α,α-dimethyl-5-phenyl-
- CBNumber:
- CB59769408
- Molecular Formula:
- C16H21IN2O2
- Molecular Weight:
- 400.26
- MDL Number:
- MOL File:
- 2573912-32-8.mol
Last updated:2023-05-21 10:59:17
Boiling point | 513.0±50.0 °C(Predicted) |
---|---|
Density | 1.46±0.1 g/cm3(Predicted) |
storage temp. | Store at -20°C |
solubility | DMSO: 80 mg/mL (199.87 mM);Ethanol: 80 mg/mL (199.87 mM) |
pka | 14.60±0.29(Predicted) |
Water Solubility | Water: Insoluble |
1H-Imidazole-1-ethanol, 2-(ethoxymethyl)-4-iodo-α,α-dimethyl-5-phenyl- price
1H-Imidazole-1-ethanol, 2-(ethoxymethyl)-4-iodo-α,α-dimethyl-5-phenyl- Chemical Properties,Uses,Production
Biological Activity
CU-CPD107 is a selective, dual-activity small-molecule which demonstrated differential activity against the TLR8 agonists and ssRNA ligands. In the presence of R848, CU-CPD107 acts as a TLR8 signaling inhibitor (IC50=13.7 μM). In the presence of ssRNA, CU-CPD107 shows synergistic agonist activities, while CU-CPD107 alone is unable to influence TLR8 signaling. CU-CPD107, a tetrasubstituted imidazole, inhibits R848-induced TLR8 signaling and shows unexpected synergistic agonist activities in the presence of ssRNA, while CU-CPD107 alone is unable to influence TLR8 signaling.[1]
References
[1] Yang Y, et al. Nat Commun. 2021 Jul 16;12(1):4351.
1H-Imidazole-1-ethanol, 2-(ethoxymethyl)-4-iodo-α,α-dimethyl-5-phenyl- Preparation Products And Raw materials
Raw materials
Preparation Products
1H-Imidazole-1-ethanol, 2-(ethoxymethyl)-4-iodo-α,α-dimethyl-5-phenyl- Suppliers
Global( 7)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
ShangHai Caerulum Pharma Discovery Co., Ltd. | 18149758185 | sales-cpd@caerulumpharma.com | China | 3466 | 58 |
DC Chemicals | 021-58447131 13564518121 | sales@dcchemicals.com | China | 9412 | 58 |
ShangHai ChuanQian Chemcial Technique Centre | 15869524721 | 3525679403@qq.com | China | 3902 | 58 |
TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24647 | 58 |
Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11975 | 58 |
RD International Technology Co., Limited | 18024082417 | market@ubiochem.com | China | 9268 | 58 |
1H-Imidazole-1-ethanol, 2-(ethoxymethyl)-4-iodo-α,α-dimethyl-5-phenyl-
CU-CPD107
2573912-32-8
C16H21IN2O2