ChemicalBook >> CAS DataBase List >>1H-Imidazole-1-ethanol, 2-(ethoxymethyl)-4-iodo-α,α-dimethyl-5-phenyl-

1H-Imidazole-1-ethanol, 2-(ethoxymethyl)-4-iodo-α,α-dimethyl-5-phenyl-

1H-Imidazole-1-ethanol, 2-(ethoxymethyl)-4-iodo-α,α-dimethyl-5-phenyl- structure

CAS No.: 2573912-32-8

Chemical Name:: 1H-Imidazole-1-ethanol, 2-(ethoxymethyl)-4-iodo-α,α-dimethyl-5-phenyl-

Synonyms: CU-CPD107;1H-Imidazole-1-ethanol, 2-(ethoxymethyl)-4-iodo-α,α-dimethyl-5-phenyl-

CBNumber:: CB59769408

Molecular Formula:: C16H21IN2O2

Molecular Weight:: 400.26

MDL Number:

MOL File:: 2573912-32-8.mol

Last updated:2023-05-21 10:59:17

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1H-Imidazole-1-ethanol, 2-(ethoxymethyl)-4-iodo-α,α-dimethyl-5-phenyl- Properties

Boiling point	513.0±50.0 °C(Predicted)
Density	1.46±0.1 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	DMSO: 80 mg/mL (199.87 mM);Ethanol: 80 mg/mL (199.87 mM)
pka	14.60±0.29(Predicted)
Water Solubility	Water: Insoluble

1H-Imidazole-1-ethanol, 2-(ethoxymethyl)-4-iodo-α,α-dimethyl-5-phenyl- price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	SML3244	CU-CPD107 ≥98% (HPLC)	2573912-32-8	5MG	$84.4	2023-01-07	Buy
Sigma-Aldrich	SML3244	CU-CPD107 ≥98% (HPLC)	2573912-32-8	25MG	$341	2023-01-07	Buy

Product number	Packaging	Price	Buy
SML3244	5MG	$84.4	Buy
SML3244	25MG	$341	Buy

1H-Imidazole-1-ethanol, 2-(ethoxymethyl)-4-iodo-α,α-dimethyl-5-phenyl- Chemical Properties,Uses,Production

Biological Activity

CU-CPD107 is a selective, dual-activity small-molecule which demonstrated differential activity against the TLR8 agonists and ssRNA ligands. In the presence of R848, CU-CPD107 acts as a TLR8 signaling inhibitor (IC50=13.7 μM). In the presence of ssRNA, CU-CPD107 shows synergistic agonist activities, while CU-CPD107 alone is unable to influence TLR8 signaling. CU-CPD107, a tetrasubstituted imidazole, inhibits R848-induced TLR8 signaling and shows unexpected synergistic agonist activities in the presence of ssRNA, while CU-CPD107 alone is unable to influence TLR8 signaling.[1]

References

[1] Yang Y, et al. Nat Commun. 2021 Jul 16;12(1):4351.

1H-Imidazole-1-ethanol, 2-(ethoxymethyl)-4-iodo-α,α-dimethyl-5-phenyl- Preparation Products And Raw materials

Raw materials

Preparation Products

1H-Imidazole-1-ethanol, 2-(ethoxymethyl)-4-iodo-α,α-dimethyl-5-phenyl- Suppliers

Global( 6)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19973	58
ShangHai Caerulum Pharma Discovery Co., Ltd.	18149758185	sales-cpd@caerulumpharma.com	China	3429	58
DC Chemicals	021-58447131 13564518121	sales@dcchemicals.com	China	9412	58
ShangHai ChuanQian Chemcial Technique Centre	15869524721	3525679403@qq.com	China	3616	58
TargetMol Chemicals Inc.	4008200310	marketing@tsbiochem.com	China	24017	58
RD International Technology Co., Limited	18024082417	market@ubiochem.com	China	9154	58

Supplier	Advantage
TargetMol Chemicals Inc.	58
ShangHai Caerulum Pharma Discovery Co., Ltd.	58
DC Chemicals	58
ShangHai ChuanQian Chemcial Technique Centre	58
TargetMol Chemicals Inc.	58
RD International Technology Co., Limited	58

1H-Imidazole-1-ethanol, 2-(ethoxymethyl)-4-iodo-α,α-dimethyl-5-phenyl- CU-CPD107 2573912-32-8 C16H21IN2O2