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RUVBL1/2 ATPase-IN-1

RUVBL1/2 ATPase-IN-1 Structure
RUVBL1/2 ATPase-IN-1 structure
CAS No.
423128-55-6
Chemical Name:
RUVBL1/2 ATPase-IN-1
Synonyms
RUVBL1/2 ATPase-IN-1;RUVBL1/2 ATPaseIN1,inhibit,Inhibitor,selective,RUVBL1/2 ATPase IN 1,cancer,RUVBL1,AAA ATPases,RUVBL2;Methanone, [5,7-dimethyl-6-[(4-methylphenyl)methyl]pyrazolo[1,5-a]pyrimidin-3-yl][4-[3-(trifluoromethyl)phenyl]-1-piperazinyl]-
CBNumber:
CB611086211
Molecular Formula:
C28H28F3N5O
Molecular Weight:
507.55
MDL Number:
MOL File:
423128-55-6.mol
Last updated:2024-07-02 08:55:12
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RUVBL1/2 ATPase-IN-1 Properties

Density 1.29±0.1 g/cm3(Predicted)
storage temp. 4°C, protect from light
solubility DMSO : 10 mg/mL (19.70 mM; ultrasonic and warming and heat to 60°C)
pka 1.33±0.20(Predicted)
form Solid
color White to off-white

RUVBL1/2 ATPase-IN-1 Chemical Properties,Uses,Production

Biological Activity

RUVBL1/2 ATPase-IN-1 (compound 18) is a potent and selective inhibitor of RUVBL1/2 ATPase with IC50 values of 6.0 and 7.7 μM, respectively. RUVBL1 and RUVBL2 are highly conserved AAA ATPases (ATPases Associated with various cellular Activities) and highly relevant to the progression of cancer. RUVBL1/2 ATPase-IN-1 has the potential for the research of cancer diseases[1].

References

[1]. Zhang G, et al. Discovery of small-molecule inhibitors of RUVBL1/2 ATPase. Bioorg Med Chem. 2022;62:116726.

RUVBL1/2 ATPase-IN-1 Preparation Products And Raw materials

Raw materials

Preparation Products

RUVBL1/2 ATPase-IN-1 Suppliers

Global( 7)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 support@targetmol.com United States 19973 58
Shanghai Chaolan Chemical Technology Center QQ:65489617 15618227136 info@SuperLan-chem.com China 9874 58
DC Chemicals 021-58447131 13564518121 sales@dcchemicals.com China 9412 58
Jingmo (Xiamen) Biotechnology Co., Ltd 13621943973 13515979683 sales@jamxmpharmatech.com China 1083 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24017 58
Nanjing Tengyi Biotechnology Co., Ltd 025-58851786 17714337195 sales@tybiochem.com China 5595 58
Jiangsu Aikon Biopharmaceutical R&D Co.,Ltd. 025-66061636 18013972705 qqyang@aikonchem.com China 5068 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
Shanghai Chaolan Chemical Technology Center 58
DC Chemicals 58
Jingmo (Xiamen) Biotechnology Co., Ltd 58
TargetMol Chemicals Inc. 58
Nanjing Tengyi Biotechnology Co., Ltd 58
Jiangsu Aikon Biopharmaceutical R&D Co.,Ltd. 58

RUVBL1/2 ATPase-IN-1 Spectrum

RUVBL1/2 ATPase-IN-1(423128-55-6)1HNMR
RUVBL1/2 ATPase-IN-1 RUVBL1/2 ATPaseIN1,inhibit,Inhibitor,selective,RUVBL1/2 ATPase IN 1,cancer,RUVBL1,AAA ATPases,RUVBL2 Methanone, [5,7-dimethyl-6-[(4-methylphenyl)methyl]pyrazolo[1,5-a]pyrimidin-3-yl][4-[3-(trifluoromethyl)phenyl]-1-piperazinyl]- 423128-55-6