Pimonidazole
- CAS No.
- 70132-50-2
- Chemical Name:
- Pimonidazole
- Synonyms
- NSC 380540;Pimonidazole;Pimonidazole USP/EP/BP;inhibit,Pimonidazole,Inhibitor;1-(2-nitroimidazol-1-yl)-3-piperidin-1-ylpropan-2-ol;alpha-((2-Nitroimidazol-1-yl)methyl)-1-piperidineethanol;α-[(2-Nitro-1H-imidazol-1-yl)methyl]-1-piperidineethanol;1-(2-Nitro-1H-imidazol-1-yl)-3-(piperidin-1-yl)propan-2-ol;1-Piperidineethanol, α-[(2-nitro-1H-imidazol-1-yl)methyl]-;1-(2-Nitro-1H-imidazol-1-yl)-3-(piperidin-1-yl)-2-propanol
- CBNumber:
- CB61179505
- Molecular Formula:
- C11H18N4O3
- Molecular Weight:
- 254.29
- MDL Number:
- MFCD00867974
- MOL File:
- 70132-50-2.mol
- MSDS File:
- SDS
| Melting point | 110-113°C |
|---|---|
| Boiling point | 490.5±55.0 °C(Predicted) |
| Density | 1.39±0.1 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | DMSO: >20mg/mL |
| pka | 14.06±0.20(Predicted) |
| form | powder |
| color | yellow |
| FDA UNII | 46JO4D76R2 |
| NCI Drug Dictionary | pimonidazole |
| UNSPSC Code | 12352200 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302 | |||||||||
| Precautionary statements | P264-P270-P301+P312-P330-P501 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22 | |||||||||
| NFPA 704 |
|
Pimonidazole price More Price(12)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | N1165 | Pimonidazole ≥98% (HPLC) | 70132-50-2 | 10mg | $168 | 2024-03-01 | Buy |
| Sigma-Aldrich | N1165 | Pimonidazole ≥98% (HPLC) | 70132-50-2 | 50mg | $405 | 2024-03-01 | Buy |
| Cayman Chemical | 89130 | Pimonidazole ≥98% | 70132-50-2 | 5mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 89130 | Pimonidazole ≥98% | 70132-50-2 | 10mg | $61 | 2024-03-01 | Buy |
| Cayman Chemical | 89130 | Pimonidazole ≥98% | 70132-50-2 | 50mg | $243 | 2024-03-01 | Buy |
Pimonidazole Chemical Properties,Uses,Production
Description
Hypoxic cells are low oxygen cells that when present in tumors are radioresistant and chemoresistant. Pimonidazole is a small molecule radiosensitizer that has proven to be an effective and nontoxic hypoxia marker for human squamous cell carcinomas of the cervix, head, and neck. This immunochemical hypoxia marker has been widely used in experimental and clinical studies due to its chemical stability, water solubility, and wide tissue distribution. It is generally administered in aqueous solution by injection.
Uses
Pimonidazole is an effective and nontoxic hypoxia detection reagent. Pimonidazole forms adducts with thiol groups in proteins, peptides and amino acids. It labels hypoxic tumor cells in vivo. Also labels hypoxic mesenchymal stem cells in mouse bone marrow.
Biochem/physiol Actions
Pimonidazole is an effective and nontoxic exogenous 2-nitroimidazole hypoxia marker. Pimonidazole forms adducts with thiol groups in proteins, peptides and amino acids.
storage
Store at -20°C
Pimonidazole Preparation Products And Raw materials
Raw materials
Preparation Products
Pimonidazole Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19552 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32159 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30231 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 | 1026@dideu.com | China | 7859 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 | |
| ShangHai Caerulum Pharma Discovery Co., Ltd. | 18149758185 18149758185 | sales-cpd@caerulumpharma.com | China | 3466 | 58 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51456 | 80 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 021-61312847; 18021002903 | 3008007409@qq.com | China | 71829 | 60 |
| Tianjin Kailiqi Biotechnology Co., Ltd. | 15076683720 | klq@cw-bio.com | China | 6187 | 55 |
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 | sales@glpbio.cn | China | 6777 | 58 |
View Lastest Price from Pimonidazole manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-18 | Pimonidazole
70132-50-2
|
US $39.00-153.00 / mg | 99.57% | 10g | TargetMol Chemicals Inc. |
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- Pimonidazole
70132-50-2
- US $39.00-153.00 / mg
- 99.57%
- TargetMol Chemicals Inc.