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Marbofloxacin

CAS No.
115550-35-1
Chemical Name:
Marbofloxacin
Synonyms
Marbofloxacine;9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-3,7-dihydro-2H-[1,3,4]oxadiazino[6,5,4-ij]quinoline-6-carboxylic acid;CS-939;Marbocyl;zeniquin;ZENIQUIN(R);Ma Bo effect;MARBOFLOXACIN;Marbifloxacin;Marboflaxacine
CBNumber:
CB6125860
Molecular Formula:
C17H19FN4O4
Molecular Weight:
362.36
MDL Number:
MFCD00864820
MOL File:
115550-35-1.mol
Last updated:2024-11-19 20:33:22

Marbofloxacin Properties

Melting point 268-269°C (dec.)
Boiling point 571℃
Density 1.55±0.1 g/cm3(Predicted)
Flash point >110°(230°F)
storage temp. Inert atmosphere,2-8°C
solubility Chloroform (Slightly, Heated)
pka 6.02±0.20(Predicted)
form Solid
color Light Yellow
Water Solubility Soluble in DMSO at 2mg/ml. Soluble in water or ethanol at <1mg/ml
Merck 14,5750
InChI InChI=1S/C17H19FN4O4/c1-19-3-5-21(6-4-19)14-12(18)7-10-13-16(14)26-9-20(2)22(13)8-11(15(10)23)17(24)25/h7-8H,3-6,9H2,1-2H3,(H,24,25)
InChIKey BPFYOAJNDMUVBL-UHFFFAOYSA-N
SMILES N12C=C(C(O)=O)C(=O)C3=C1C(=C(N1CCN(C)CC1)C(F)=C3)OCN2C
CAS DataBase Reference 115550-35-1(CAS DataBase Reference)
FDA UNII 8X09WU898T

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H412
Precautionary statements  P273-P501
Hazard Codes  Xi
Risk Statements  52/53-36/37/38
Safety Statements  61-36-26-60
WGK Germany  2
RTECS  UU8815140
HS Code  29349990
NFPA 704
0
1 0

Marbofloxacin price More Price(39)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich Y0000819 Marbofloxacin European Pharmacopoeia (EP) Reference Standard 115550-35-1 y0000819 $220 2024-03-01 Buy
Sigma-Aldrich 34039 Marbofloxacin VETRANAL?, analytical standard 115550-35-1 100MG $137 2024-03-01 Buy
TCI Chemical M2240 Marbofloxacin >98.0%(HPLC)(T) 115550-35-1 1g $158 2024-03-01 Buy
TCI Chemical M2240 Marbofloxacin >98.0%(HPLC)(T) 115550-35-1 5g $466 2024-03-01 Buy
Alfa Aesar J66407 Marbofloxacin, 99.7% 115550-35-1 50mg $131 2021-12-16 Buy
Product number Packaging Price Buy
Y0000819 y0000819 $220 Buy
34039 100MG $137 Buy
M2240 1g $158 Buy
M2240 5g $466 Buy
J66407 50mg $131 Buy

Marbofloxacin Chemical Properties,Uses,Production

Brand Name(s) in US

Zeniquin, Marbocyl

Description

Marbofloxacin is a fluoroquinolone antibiotic that is active against P. multocida in vitro (MIC = 0.016 μg/ml). It exhibits broad-spectrum antibacterial activity mediated by the inhibition of DNA gyrase, with MIC values ranging from 0.016 to 0.4 and 0.19 to 1.7 μg/ml against various Gram-negative and Gram-positive bacterial isolates, respectively. In vivo, the administration of marbofloxacin (2 mg/kg, i.m.) after infection prevents the formation of pulmonary lesions in a bovine calf model of M. haemolytica A1 pneumonia. Oral marbofloxacin (2 mg/kg per day) also exhibits antileishmanial activity in a canine model of leishmaniasis, decreasing parasitic load by 72%. Formulations containing marbofloxacin have been used in the veterinary treatment of bacterial infections.

Chemical Properties

Crystalline Solid

Uses

A broad spectrum antibiotic commonly used to target Pseudomonas and Staphylococci species

Uses

Fluorinated quinolone antibacterial

Definition

ChEBI: A fluoroquinolone antibiotic that is 7-oxo-2,3-dihydro-7H-[1,3,4]oxadiazino[6,5,4-ij]quinoline substituted at positions 6, 9 and 10 by carboxy, fluoro and 4-methylpiperazin-1-yl groups, respectively. A synthetic, broad spect um bactericidal agent, it is used in veterinary medicine, although its mechanism of action is not thoroughly understood.

Application

Marbofloxacin is an FDA-approved broad-spectrum bactericidal fluoroquinolone available in oral tablet and injectable forms. It has been shown to have varying therapeutic effects in a wide range of animal diseases in dogs, cats, horses, cattle and pigs. It can be used to treat skin and soft tissue infections in dogs and cats, urinary tract infections in dogs, some blood borne pathogens (e.g. Mycoplasma haematobium) in cats, equine infections caused by susceptible bacteria, bovine respiratory disease, and porcine respiratory disease pathogens.

Side effects

The most common side effects of Marbofloxacin are vomiting, diarrhoea and loss of appetite. More serious side effects include cartilage abnormalities (which may cause difficulty walking), prolonged loss of appetite, incoordination, convulsions, depression, fever, rash, or difficulty breathing. Blindness and eye damage in cats has been a concern at high doses.

Veterinary Drugs and Treatments

Marbofloxacin is labeled for the treatment of susceptible bacterial infections in dogs and cats.

Marbofloxacin Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 412)Suppliers
Supplier Tel Email Country ProdList Advantage
Hpets Biotech Company (Chongqing) Co.,ltd
+8613340353813 info@hanpets.com China 26 58
shandong perfect biotechnology co.ltd
+86-53169958659 +86-13153181156 sales@sdperfect.com China 294 58
Hebei Weibang Biotechnology Co., Ltd
+8615531157085 abby@weibangbio.com China 8811 58
Shaanxi Dideu Medichem Co. Ltd
+86-29-81148696 +86-15536356810 1022@dideu.com China 3882 58
Hebei Mojin Biotechnology Co., Ltd
+86 13288715578 +8613288715578 sales@hbmojin.com China 12839 58
Hebei Chuanghai Biotechnology Co,.LTD
+86-13131129325 sales1@chuanghaibio.com China 5892 58
Anhui Ruihan Technology Co., Ltd
+8617756083858 daisy@anhuiruihan.com China 973 58
Nantong Guangyuan Chemicl Co,Ltd
+undefined17712220823 admin@guyunchem.com China 615 58
Shaanxi TNJONE Pharmaceutical Co., Ltd
+8618092446649 sarah@tnjone.com China 1143 58
Henan Suikang Pharmaceutical Co.,Ltd.
+86-18239973690 +86-18239973690 sales@suikangpharm.com China 311 58

Related articles

View Lastest Price from Marbofloxacin manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Marbofloxacin pictures 2024-11-25 Marbofloxacin
115550-35-1
US $0.00 / kg 25kg 99% 10tons Henan Suikang Pharmaceutical Co.,Ltd.
Marbofloxacin pictures 2024-11-22 Marbofloxacin
115550-35-1
US $1.00 / KG 1KG 99.0% ~ 101.0% 50KG/month WUHAN FORTUNA CHEMICAL CO., LTD
Marbifloxacin pictures 2024-11-22 Marbifloxacin
115550-35-1
US $1.00 / kg 1kg 99 100 S&Y Biochem Co.,Ltd
  • Marbofloxacin pictures
  • Marbofloxacin
    115550-35-1
  • US $0.00 / kg
  • 99%
  • Henan Suikang Pharmaceutical Co.,Ltd.
  • Marbofloxacin pictures
  • Marbofloxacin
    115550-35-1
  • US $1.00 / KG
  • 99.0% ~ 101.0%
  • WUHAN FORTUNA CHEMICAL CO., LTD

Marbofloxacin Spectrum

7h-pyrido(3,2,1-ij)(4,1,2)benzoxadiazine-6-carboxylicacid,2,3-dihydro-9-fluor o-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo- MARBOFLOXACIN Marbofloxacin, >=99% 9-FLUORO-2,3-DIHYDRO-3-METHYL-10-(4-METHYL-PIPERAZINO)-7-OXO-7H-PYRIDO[1,2,3-IJ][1,2,4]BENZOXADIAZINE-6-CARBOXYLIC ACID ZENIQUIN(R) Marbofloxacin, Vetranal 7H-Pyrido3,2,1-ij4,1,2benzoxadiazine-6-carboxylic acid, 9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo- zeniquin 9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[3,2,1-ij][4,1,2]benzoxadiazine-6-carboxylic Acid Marbocyl Zeniquin(R), 9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-piperazino)-7-oxo-7H-pyrido[1,2,3-ij][1,2,4]benzoxadiazine-6-carboxylic acid 9-Fluoro-3,7-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2H-[1,3,4]oxadiazino[6,5,4-ij]quinoline-6-carboxylic Acid 8-Fluoro-3-methyl-9-(4-methyl-piperazin-1-yl)-6-oxo-2,3-dihydro-1H,6H-1,3,3a-triaza-phenalene-5-carboxylic acid Marbofloxacin Solution, 1000ppm Marbofloxacin Solution, 100ppm CS-939 Marbofloxacin for peak identification CRS Marbofloxacin Standard Marbofloxacin> Marbofloxacin CRS Marbofloxacin Solution in Methanol, 1000μg/mL Marboflaxacine Marbofloxacin USP/EP/BP MarbofloxacinQ: What is Marbofloxacin Q: What is the CAS Number of Marbofloxacin Q: What is the storage condition of Marbofloxacin Q: What are the applications of Marbofloxacin Marbofloxacine 9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-3,7-dihydro-2H-[1,3,4]oxadiazino[6,5,4-ij]quinoline-6-carboxylic acid Ma Bo effect 9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-piperazino)-7-oxo-7h-pyrido[1,2,3-ij][1,2,4]benzoxadiazine-6-carboxylic acid zeniquin 9-Fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-3,7-dihydro-2H-[1,3,4]oxadiazino[6,5,4-ij]quinoline-6-carboxylicacid,98+% Marbofloxacin EP/BP Marbofloxacine|||Zeniquin|||Marbocyl Marbifloxacin Marbofloxacin in Methanol Marbofloxacin 100 μg/ml Methanol C14755000 Marbofloxacin 115550-35-1 11550-35-1 C17H19FN4O4 C17H19N4O4F API Active Pharmaceutical Ingredients Aromatics Compounds Aromatics Heterocycles Intermediates & Fine Chemicals Pharmaceuticals 115550-35-1