Marbofloxacin
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Marbofloxacin 속성
- 녹는점
- 268-269°C (dec.)
- 끓는 점
- 571℃
- 밀도
- 1.55±0.1 g/cm3(Predicted)
- 인화점
- >110°(230°F)
- 저장 조건
- Inert atmosphere,2-8°C
- 용해도
- 클로로포름(약간 용해됨 가열)
- 산도 계수 (pKa)
- 6.02±0.20(Predicted)
- 물리적 상태
- Solid
- 색상
- 연노랑
- 수용성
- 2mg/ml의 DMSO에 용해됩니다. <1mg/ml에서 물 또는 에탄올에 용해됨
- Merck
- 14,5750
- InChI
- InChI=1S/C17H19FN4O4/c1-19-3-5-21(6-4-19)14-12(18)7-10-13-16(14)26-9-20(2)22(13)8-11(15(10)23)17(24)25/h7-8H,3-6,9H2,1-2H3,(H,24,25)
- InChIKey
- BPFYOAJNDMUVBL-UHFFFAOYSA-N
- SMILES
- N12C=C(C(O)=O)C(=O)C3=C1C(=C(N1CCN(C)CC1)C(F)=C3)OCN2C
- CAS 데이터베이스
- 115550-35-1(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | Xi | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 52/53-36/37/38 | ||
| 안전지침서 | 61-36-26-60 | ||
| WGK 독일 | 2 | ||
| RTECS 번호 | UU8815140 | ||
| HS 번호 | 29349990 |
Marbofloxacin C화학적 특성, 용도, 생산
개요
Marbofloxacin is a fluoroquinolone antibiotic that is active against P. multocida in vitro (MIC = 0.016 μg/ml). It exhibits broad-spectrum antibacterial activity mediated by the inhibition of DNA gyrase, with MIC values ranging from 0.016 to 0.4 and 0.19 to 1.7 μg/ml against various Gram-negative and Gram-positive bacterial isolates, respectively. In vivo, the administration of marbofloxacin (2 mg/kg, i.m.) after infection prevents the formation of pulmonary lesions in a bovine calf model of M. haemolytica A1 pneumonia. Oral marbofloxacin (2 mg/kg per day) also exhibits antileishmanial activity in a canine model of leishmaniasis, decreasing parasitic load by 72%. Formulations containing marbofloxacin have been used in the veterinary treatment of bacterial infections.화학적 성질
Crystalline Solid용도
Fluorinated quinolone antibacterial정의
ChEBI: A fluoroquinolone antibiotic that is 7-oxo-2,3-dihydro-7H-[1,3,4]oxadiazino[6,5,4-ij]quinoline substituted at positions 6, 9 and 10 by carboxy, fluoro and 4-methylpiperazin-1-yl groups, respectively. A synthetic, broad spect um bactericidal agent, it is used in veterinary medicine, although its mechanism of action is not thoroughly understood.부작용
The most common side effects of Marbofloxacin are vomiting, diarrhoea and loss of appetite. More serious side effects include cartilage abnormalities (which may cause difficulty walking), prolonged loss of appetite, incoordination, convulsions, depression, fever, rash, or difficulty breathing. Blindness and eye damage in cats has been a concern at high doses.Marbofloxacin 준비 용품 및 원자재
원자재
준비 용품
Marbofloxacin 공급 업체
글로벌( 417)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Hpets Biotech Company (Chongqing) Co.,ltd | +8613340353813 |
info@hanpets.com | China | 26 | 58 |
| shandong perfect biotechnology co.ltd | +86-53169958659 +86-13153181156 |
sales@sdperfect.com | China | 294 | 58 |
| Hebei Weibang Biotechnology Co., Ltd | +8615531157085 |
abby@weibangbio.com | China | 8806 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-81148696 +86-15536356810 |
1022@dideu.com | China | 3882 | 58 |
| Hebei Mujin Biotechnology Co.,Ltd | +86 13288715578 +8613288715578 |
sales@hbmojin.com | China | 12832 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 |
sales1@chuanghaibio.com | China | 5889 | 58 |
| Anhui Ruihan Technology Co., Ltd | +8617756083858 |
daisy@anhuiruihan.com | China | 973 | 58 |
| Nantong Guangyuan Chemicl Co,Ltd | +undefined17712220823 |
admin@guyunchem.com | China | 615 | 58 |
| Shaanxi TNJONE Pharmaceutical Co., Ltd | +8618092446649 |
sarah@tnjone.com | China | 1143 | 58 |
| Henan Suikang Pharmaceutical Co.,Ltd. | +86-18239973690 +86-18239973690 |
sales@suikangpharm.com | China | 311 | 58 |