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YM 15430-1

CAS No.
153192-22-4
Chemical Name:
YM 15430-1
Synonyms
YM-15430;YM-15430-3;YM-15430-2;YM 15430-1;3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 3-[4-[[(2S)-2-hydroxy-3-phenoxypropyl]amino]butyl] 5-methyl ester, (4S)-
CBNumber:
CB61313624
Molecular Formula:
C29H35N3O8
Molecular Weight:
553.6
MDL Number:
MFCD00892255
MOL File:
153192-22-4.mol
Last updated:2023-03-31 09:12:58

YM 15430-1 Properties

Boiling point 729.3±60.0 °C(Predicted)
Density 1.240±0.06 g/cm3(Predicted)
pka 13.98±0.20(Predicted)

YM 15430-1 Chemical Properties,Uses,Production

Description

YM-430, also known as YM-15430; YM-154301; is a dual of β1 adrenergic receptor antagonist and calcium channel antagonist. YM430 could be both an antianginal and antihypertensive agent, because of its dual activities. YM430 (10(-8)-10(-6) M) inhibited 3,4-diaminopyridine-induced rhythmic contractions with an IC50 value of 59.2 nM. In anesthetized rats, YM430 (10-100 mg/kg PO) inhibited arginine vasopressin-induced ST-segment depression with an IC50 value of 36.6 mg/kg PO. YM430 may be of value in the treatment of various types of angina pectoris such as variant and stable angina.

YM 15430-1 Preparation Products And Raw materials

Raw materials

Preparation Products

YM 15430-1 Suppliers

Global( 4)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354 support@targetmol.com United States 19973 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24017 58
Suzhou Meishi Biotechnology Co., Ltd. 1173954148q meishipharma@126.com China 20035 58
YM 15430-1 YM-15430 YM-15430-2 YM-15430-3 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 3-[4-[[(2S)-2-hydroxy-3-phenoxypropyl]amino]butyl] 5-methyl ester, (4S)- 153192-22-4