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coclaurine

coclaurine structure

CAS No.: 486-39-5

Chemical Name:: coclaurine

Synonyms: (S)-Coclaurine;Caclaurine;(S)-colaurine;(-)-Coclaurine;(RS)-coclaurine;Sufentanil Impurity 10;(S)-1-(4-Hydroxybenzyl)-6-methoxy-1,2,3,4-tetrahydroisoquinolin-7-ol;(S)-1-(4-Hydroxybenzyl)-6-methoxy-1,2,3,4-tetrahydroisoquinoline-7-ol;[S,(+)]-1,2,3,4-Tetrahydro-1-(4-hydroxybenzyl)-6-methoxyisoquinolin-7-ol;(1S)-1,2,3,4-Tetrahydro-1-[(4-hydroxyphenyl)methyl]-6-methoxyisoquinolin-7-ol

CBNumber:: CB61374689

Molecular Formula:: C17H19NO3

Molecular Weight:: 285.34

MDL Number:

MOL File:: 486-39-5.mol

MSDS File:: SDS

Last updated:2025-04-17 18:22:24

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coclaurine Properties

Melting point	220-221°
Boiling point	427.77°C (rough estimate)
Density	1.0864 (rough estimate)
refractive index	1.5400 (estimate)
solubility	Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form	Powder
pka	10.00±0.15(Predicted)
color	White to off-white
FDA UNII	CW1576313Y

coclaurine price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
American Custom Chemicals Corporation	API0016420	COCLAURINE 95.00%	486-39-5	5MG	$502.91	2021-12-16	Buy
ChemScene	CS-0023935	Coclaurine	486-39-5	5mg	$1350	2021-12-16	Buy
Medical Isotopes, Inc.	74135	Coclaurine 98%	486-39-5	10mg	$1900	2021-12-16	Buy
Arctom	CFN98769	Coclaurine ≥98%	486-39-5	5mg	$513	2021-12-16	Buy
Crysdot	CD32001265	Coclaurine 95+%	486-39-5	5mg	$810	2021-12-16	Buy

Product number	Packaging	Price	Buy
API0016420	5MG	$502.91	Buy
CS-0023935	5mg	$1350	Buy
74135	10mg	$1900	Buy
CFN98769	5mg	$513	Buy
CD32001265	5mg	$810	Buy

coclaurine Chemical Properties,Uses,Production

Uses

Coclaurine is a class of tetrahydroisoquinoline alkaloids that can be isolated from Sarcopetalum harveyanum. Coclaurine is a nicotinic acetylcholine receptor (nAChRs) antagonist[1][2].

Definition

ChEBI: The (S)-enantiomer of coclaurine.

target

Calcium Channel

References

[1] Sowemimo BO, et al. The isolation of stepharine and coclaurine from Sarcopetalum harveyanum. Lloydia. 1972 Mar;35(1):90-1. PMID:5037484
[2] Matthew J. Cheesman . Oceania: Antidepressant Medicinal Plants. Herbal Medicine in Depression. 2016, 483-527.

coclaurine Preparation Products And Raw materials

Raw materials

l-O-Methylarmepavine Demethyl-Coclaurine

Preparation Products

coclaurine Suppliers

Global( 79)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22963	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19552	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29808	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32222	58
Aktin Chemicals, Inc.	028-85159085	info@aktinchem.com	CHINA	1025	58
ANHUI WITOP BIOTECH CO., LTD	+8615255079626	eric@witopchemical.com	China	23541	58
LEAP CHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	24727	58
TargetMol Chemicals Inc.		support@targetmol.com	United States	38642	58
Jiangxi Baicaoyuan Biotechnology Co. , Ltd.	0791-82165230 17707911324	2279635539@qq.com	China	1387	58

Supplier	Advantage
ATK CHEMICAL COMPANY LIMITED	60
Hubei xin bonus chemical co. LTD	58
BOC Sciences	58
career henan chemical co	58
TargetMol Chemicals Inc.	58
Aktin Chemicals, Inc.	58
ANHUI WITOP BIOTECH CO., LTD	58
LEAP CHEM CO., LTD.	58
TargetMol Chemicals Inc.	58
Jiangxi Baicaoyuan Biotechnology Co. , Ltd.	58

View Lastest Price from coclaurine manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2024-11-19	(S)-Coclaurine 486-39-5	US $188.00-783.00 / mg			10g	TargetMol Chemicals Inc.
	2020-01-10	7-Isoquinolinol,1,2,3,4-tetrahydro-1-[(4-hydroxyphenyl)methyl]-6-methoxy-, (1S)- 486-39-5	US $9.80 / KG	1KG	≥98%	20 tons	Career Henan Chemical Co

(S)-Coclaurine
486-39-5
US $188.00-783.00 / mg
TargetMol Chemicals Inc.

7-Isoquinolinol,1,2,3,4-tetrahydro-1-[(4-hydroxyphenyl)methyl]-6-methoxy-, (1S)-
486-39-5
US $9.80 / KG
≥98%
Career Henan Chemical Co

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(1S)-1,2,3,4-Tetrahydro-1-[(4-hydroxyphenyl)methyl]-6-methoxyisoquinolin-7-ol (S)-1-(4-Hydroxybenzyl)-6-methoxy-1,2,3,4-tetrahydroisoquinoline-7-ol [S,(+)]-1,2,3,4-Tetrahydro-1-(4-hydroxybenzyl)-6-methoxyisoquinolin-7-ol (S)-colaurine (RS)-coclaurine 7-Isoquinolinol,1,2,3,4-tetrahydro-1-[(4-hydroxyphenyl)methyl]-6-methoxy-, (1S)- Caclaurine (S)-Coclaurine (-)-Coclaurine (S)-1-(4-Hydroxybenzyl)-6-methoxy-1,2,3,4-tetrahydroisoquinolin-7-ol Sufentanil Impurity 10 486-39-5