ChemicalBook >> CAS DataBase List >>(1R,2R)-B13
(1R,2R)-B13
- CAS No.
- 35922-06-6
- Chemical Name:
- (1R,2R)-B13
- Synonyms
- CAY10466;D-NMAPPD;(1R,2R)-B13;D-NMAPPD Exclusive;N-[(1R,2R)-2-HYDROXY-1-(HYDROXYMETHYL)-2-(4-NITROPHENYL)ETHYL]-TETRADECANAMIDE;Tetradecanamide, N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]-
- CBNumber:
- CB6143493
- Molecular Formula:
- C23H38N2O5
- Molecular Weight:
- 422.56
- MDL Number:
- MFCD08062172
- MOL File:
- 35922-06-6.mol
Last updated:2025-01-27 09:38:02
| Boiling point | 636.2±55.0 °C(Predicted) |
|---|---|
| Density | 1.101±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | DMF: 10 mg/ml; DMSO: 10 mg/ml; Ethanol: 20 mg/ml; Ethanol:PBS (pH 7.2)(1:2): .3 mg/ml |
| form | A crystalline solid |
| pka | 12.72±0.20(Predicted) |
| color | white to beige |
| optical activity | [α]/D -28 to -34, c =0.1 in chloroform-d |
| UNSPSC Code | 12352200 |
(1R,2R)-B13 price More Price(11)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML2358 | D-NMAPPD ≥98% (HPLC) | 35922-06-6 | 5MG | $79 | 2023-06-20 | Buy |
| Sigma-Aldrich | SML2358 | D-NMAPPD ≥98% (HPLC) | 35922-06-6 | 25MG | $319 | 2023-06-20 | Buy |
| Cayman Chemical | 10006305 | D-NMAPPD ≥98% | 35922-06-6 | 1mg | $29 | 2024-03-01 | Buy |
| Cayman Chemical | 10006305 | D-NMAPPD ≥98% | 35922-06-6 | 5mg | $107 | 2024-03-01 | Buy |
| Cayman Chemical | 10006305 | D-NMAPPD ≥98% | 35922-06-6 | 10mg | $197 | 2024-03-01 | Buy |
(1R,2R)-B13 Chemical Properties,Uses,Production
Uses
D-NMAPPD is d-NMAPPD is a potent Acid Ceramidase inhibitor that induces apoptosis..
Biological Activity
D-NMAPPD (B13), a myristoyl-CoA analog, is a cell penetrant inhibitor of N-myristoyltransferases th at suppressed FRS2α (fibroblast growth factor receptor substrate 2) myristoylation. D-NMAPPD inhibits wild-type FGFRs and drug-resistant mutants (FGFRsDRM) oncogenic signaling in cancer cells. D-NMAPPD potently inhibits growth of xenograft tumors in mice. D-NMAPPD is a potent inhibitor of ceramidase th at elevates endogenous ceramide levels and suppress growth of cancer cells.
(1R,2R)-B13 Preparation Products And Raw materials
Raw materials
Preparation Products
(1R,2R)-B13 Suppliers
Global( 28)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32161 | 58 |
| BOC Sciences | -- | info@bocsci.com | USA | 0 | 65 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11218 | 58 |
| MedBioPharmaceutical Technology Inc | 021-69568360 18916172912 | order@med-bio.cn | China | 8140 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing@energy-chemical.com | China | 44918 | 58 |
| Changzhou Furuisi Biotechnology Co., Ltd | 0519-85524369 | 3477467573@qq.com | China | 8617 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24644 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11974 | 58 |
| Shanghai Beiwanta Biotechnology Co., Ltd. | 021-67187366 19901745723 | info@bwtlab.com | China | 9358 | 58 |
| RD International Technology Co., Limited | 18024082417 | market@ubiochem.com | China | 9266 | 58 |
35922-06-6((1R,2R)-B13)Related Search:
(1R,2R)-B13
D-NMAPPD Exclusive
N-[(1R,2R)-2-HYDROXY-1-(HYDROXYMETHYL)-2-(4-NITROPHENYL)ETHYL]-TETRADECANAMIDE
D-NMAPPD
CAY10466
Tetradecanamide, N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]-
35922-06-6